Interactor 1: SYNE2 (Q8WXH0)
Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)
Gene: SYNE2
Interactor 2: SUN2 (Q9UH99)
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2)
Gene: SUN2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 1.00 | 0.939 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22632968, 30833792, 22555292, 33058875, 19933576 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, pull down, molecular sieving, comigration in non denaturing gel electrophoresis, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | KASH~Sad1_UNC |
| Common GO terms | GO:0005635 - nuclear envelope GO:0007097 - nuclear migration GO:0021817 - nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration GO:0030335 - positive regulation of cell migration GO:0031022 - nuclear migration along microfilament and 4 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
