Interactor 1: SORC1 (Q8WY21)
VPS10 domain-containing receptor SorCS1 (hSorCS)
Gene: SORCS1

Interactor 2: SORT (Q99523)
Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)
Gene: SORT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 12482870, 24128306
Identification Methods pull down, surface plasmon resonance, electron microscopy
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Sortilin-Vps10~Sortilin-Vps10, Sortilin_C~Sortilin-Vps10
Common GO terms GO:0005794 - Golgi apparatus
GO:0007218 - neuropeptide signaling pathway
GO:0016020 - membrane
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1168
Hs

1 831
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024