Protein: GPC4
Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4]

Gene: GPC4
Organism: Homo sapiens
Interactions: 75
UniProt ID: O75487

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005796 - Golgi lumen
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0009966 - regulation of signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

266585

GPC6
Glypican-6 [Cleaved into: Secreted glypican-6]

2

0

High-throughput

0.770

High

266534

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

2

High-throughput

0.691

High

266571

CAMKV
CaM kinase-like vesicle-associated protein

3

3

High-throughput

0.675

High

266535

GP183
G-protein coupled receptor 183

3

3

High-throughput

0.667

High

182061

PDPK1
3-phosphoinositide-dependent protein kinase 1

3

3

High-throughput

0.650

High

266537

SRP14
Signal recognition particle 14 kDa protein

2

1

High-throughput

0.628

High

266570

MINK1
Misshapen-like kinase 1

2

1

High-throughput

0.611

High

266580

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

266551

SG2A2
Mammaglobin-A

2

2

High-throughput

0.574

High

266554

SPCS2
Signal peptidase complex subunit 2

2

2

High-throughput

0.574

High

266561

MPPE1
Metallophosphoesterase 1

2

1

High-throughput

0.574

High

266552

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

8

Small-scale

0.561

High

266563

IFIX
Pyrin and HIN domain-containing protein 1

2

3

High-throughput

0.558

High

266520

FGF1
Fibroblast growth factor 1

1

8

High-throughput

0.536

High

266521

HEPS
Serine protease hepsin

1

12

High-throughput

0.536

High

266526

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

266533

CALX
Calnexin

1

3

High-throughput

0.536

High

266553

SQSTM
Sequestosome-1

1

1

High-throughput

0.536

High

266558

CL12B
C-type lectin domain family 12 member B

1

5

High-throughput

0.536

High

266568

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

9

High-throughput

0.536

High

266576

HBEGF
Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor

1

1

High-throughput

0.536

High

266578

TMPSD
Transmembrane protease serine 13

1

12

High-throughput

0.536

High

266581

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

1

High-throughput

0.536

High

266584

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.536

High

266527

SRF
Serum response factor

1

0

High-throughput

0.513

High

266529

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

266536

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

0

High-throughput

0.513

High

266542

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

266544

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

266556

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

266523

FGF2
Fibroblast growth factor 2

1

8

Small-scale

0.501

High

266524

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

8

Small-scale

0.501

High

266530

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

8

Small-scale

0.501

High

266546

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.501

High

266583

ALK
ALK tyrosine kinase receptor

1

1

High-throughput

0.500

High

266516

SG2A1
Mammaglobin-B

1

2

High-throughput

0.489

High

266522

FGF4
Fibroblast growth factor 4

1

8

High-throughput

0.489

High

266539

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.489

High

266543

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.489

High

266567

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

1

9

High-throughput

0.489

High

266586

SPCS1
Signal peptidase complex subunit 1

1

1

High-throughput

0.489

High

266531

CCNC
Cyclin-C

1

0

High-throughput

0.486

High

266575

AB17A
Alpha/beta hydrolase domain-containing protein 17A

1

0

High-throughput

0.486

High

266577

AKAP9
A-kinase anchor protein 9

1

2

High-throughput

0.481

High

177752

TMPS2
Transmembrane protease serine 2

1

12

High-throughput

0.479

High

241399

H2B1K
Histone H2B type 1-K

1

1

High-throughput

0.479

High

266540

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

266541

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

266548

TF65
Transcription factor p65

1

4

High-throughput

0.479

High

266549

REL
Proto-oncogene c-Rel

1

4

High-throughput

0.479

High

266557

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

266559

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

266574

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.479

High

266582

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.479

High

266518

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

266519

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

266528

CD36
Platelet glycoprotein 4

1

0

Small-scale

0.458

High

266532

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

266538

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

266550

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

266560

MIDN
Midnolin

1

0

High-throughput

0.458

High

266565

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

266517

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

High-throughput

0.445

High

266566

CLC4G
C-type lectin domain family 4 member G

1

1

Small-scale

0.445

High

179005

TNC18
Trinucleotide repeat-containing gene 18 protein

1

1

High-throughput

0.437

High

266555

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.437

High

266579

Q9H4D1
Protein kinase

1

3

High-throughput

0.437

High

266525

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.426

High

266545

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.407

High

266547

LCN6
Epididymal-specific lipocalin-6

1

0

High-throughput

0.279

Low

266564

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

266572

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

266573

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

0

High-throughput

0.279

Low

266569

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

266562

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024