HitPredict

Interactor 1: DLG2 (Q91XM9)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Interactor 2: DLGP1 (Q9D415)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: Dlgap1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007268 - chemical synaptic transmission GO:0014069 - postsynaptic density GO:0044877 - protein-containing complex binding GO:0045211 - postsynaptic membrane GO:0098919 - structural constituent of postsynaptic density and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 852 Mm			1 992
+	Rn
		956992 DLG2_RAT (1-852): 0: 768: 99.77		DLGP1_RAT (1-992): 0: 1344: 98.49
+	Hs
		145949 DLG2_HUMAN (1-852): 0: 745: 94.83		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Hs
		1077291 DLG2_HUMAN (1-852): 0: 745: 94.83		DLGP2_HUMAN (1-992): 0: 1081: 51.69
+	Hs
		327239 DLG2_HUMAN (1-852): 0: 745: 94.83		DLGP3_HUMAN (1-992): 0: 986: 37.16
+	Hs
		1077280 DLG2_HUMAN (1-852): 0: 745: 94.83		Q6IS01_HUMAN (1-539): 0: 809: 93.88
+	Mm
		1195008 DLG1_MOUSE (275-572): 1.82e-19: 96: 17.76		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Rn
		677775 DLG4_RAT (375-572): 2.06e-19: 95.6: 25.24		DLGP1_RAT (1-992): 0: 1344: 98.49
+	Hs
		145947 DLG1_HUMAN (266-572): 4.6e-20: 97.9: 17.89		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Hs
		145945 DLG4_HUMAN (375-572): 2.27e-19: 95.2: 25.24		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Hs
		1021580 DLG1_HUMAN (266-572): 4.6e-20: 97.9: 17.89		DLGP2_HUMAN (1-992): 0: 1081: 51.69
+	Hs
		4617 DLG1_HUMAN (266-572): 4.6e-20: 97.9: 17.89		A0A1B0GTN4_HUMAN (1-992): 0: 1080: 51.69
+	Hs
		942392 DLG4_HUMAN (375-572): 2.27e-19: 95.2: 25.24		DLGP2_HUMAN (1-992): 0: 1081: 51.69
+	Hs
		1021594 DLG1_HUMAN (266-572): 4.6e-20: 97.9: 17.89		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Hs
		942402 DLG4_HUMAN (375-572): 2.27e-19: 95.2: 25.24		DLGP4_HUMAN (1-992): 0: 1071: 46.37
+	Rn
		677776 DLG4_RAT (375-572): 2.06e-19: 95.6: 25.24		DLGP2_RAT (1-992): 0: 1067: 50.34
+	Mm
		69918 DLG4_MOUSE (375-572): 2.79e-19: 95.2: 25.24		DLGP4_MOUSE (1-992): 0: 1056: 45.88
+	Rn
		677778 DLG4_RAT (375-572): 2.06e-19: 95.6: 25.24		DLGP4_RAT (1-992): 0: 1027: 45.88
+	Hs
		327234 DLG4_HUMAN (375-572): 2.27e-19: 95.2: 25.24		DLGP3_HUMAN (1-992): 0: 986: 37.16
+	Mm
		1143344 DLG4_MOUSE (375-572): 2.79e-19: 95.2: 25.24		DLGP3_MOUSE (1-992): 0: 978: 38.13
+	Rn
		677777 DLG4_RAT (375-572): 2.06e-19: 95.6: 25.24		DLGP3_RAT (1-992): 0: 968: 37.85