HitPredict

Interactor 1: CLC2B (Q92478)
C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
Gene: CLEC2B

Interactor 2: JAG2 (Q9Y219)
Protein jagged-2 (Jagged2) (hJ2)
Gene: JAG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EGF~Lectin_C
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 149 Hs			1 1238
+	Hs
		1292818 PGCB_HUMAN (8-146): 1.28e-43: 154: 18.54		JAG2_HUMAN (1-1238): 0: 620: 100.00
+	Hs
		644659 NKG2A_HUMAN (8-148): 1.03e-39: 135: 26.75		JAG2_HUMAN (1-1238): 0: 620: 100.00
+	Hs
		1100824 CL12B_HUMAN (19-146): 3.08e-35: 124: 31.66		JAG2_HUMAN (1-1238): 0: 620: 100.00
+	Hs
		980478 CLC2B_HUMAN (1-149): 1.2e-43: 142: 100.00		NOTC2_HUMAN (349-1182): 3.62e-87: 314: 24.13
+	Hs
		804301 CLC2B_HUMAN (1-149): 1.2e-43: 142: 100.00		NOTC1_HUMAN (349-1237): 5.55e-86: 311: 22.95
+	Hs
		417469 FCER2_HUMAN (27-146): 3.42e-38: 133: 28.46		NOTC2_HUMAN (349-1182): 3.62e-87: 314: 24.13
+	Hs
		149947 NCAN_HUMAN (8-146): 1.55e-45: 160: 19.21		TENA_HUMAN (29-215): 1.96e-16: 87.3: 11.70
+	Rn
		70327 G3V8R2_RAT (8-146): 3.25e-46: 162: 20.53		B2LYI9_RAT (18-215): 4.89e-13: 76.1: 9.24
+	Hs
		530367 CSPG2_HUMAN (8-146): 6.11e-44: 155: 21.85		FBN1_HUMAN (542-1143): 1.57e-11: 71.5: 13.53