HitPredict

Interactor 1: BAP1 (Q92560)
Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)
Gene: BAP1

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27705803, 35446349
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000278 - mitotic cell cycle GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 729 Hs			1 449
+	Hs
		933551 BAP1_HUMAN (1-729): 0: 1185: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		933297 BAP1_HUMAN (1-729): 0: 1185: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428341 BAP1_HUMAN (1-729): 0: 1185: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		1267136 BAP1_HUMAN (1-729): 0: 1185: 100.00		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		933916 BAP1_HUMAN (1-729): 0: 1185: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		933685 UCHL5_HUMAN (5-324): 7.45e-131: 392: 35.71		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		548087 UCHL3_HUMAN (2-236): 3.91e-78: 251: 23.05		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		548088 UCHL3_HUMAN (2-236): 3.91e-78: 251: 23.05		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		456598 UCHL1_HUMAN (7-236): 1.69e-68: 226: 22.27		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Mm
		933745 UCHL1_MOUSE (7-236): 9.46e-67: 221: 22.69		TBA1A_MOUSE (1-439): 0: 715: 99.09
+	Hs
		456638 UCHL1_HUMAN (7-236): 1.69e-68: 226: 22.27		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Dm
		415599 CALYP_DROME (617-712): 1.15e-39: 154: 43.14		TBA1_DROME (1-439): 0: 714: 97.27