Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
CASP8
Caspase-8 |
28 |
18 |
Small-scale |
0.992 | High |
|
|
FADD
FAS-associated death domain protein |
13 |
16 |
Small-scale |
0.981 | High |
|
|
CASPA
Caspase-10 |
5 |
18 |
Small-scale |
0.932 | High |
|
|
RAF1
RAF proto-oncogene serine/threonine-protein kinase |
3 |
3 |
Small-scale |
0.850 | High |
|
|
DEDD
Death effector domain-containing protein |
3 |
5 |
Small-scale |
0.834 | High |
|
|
DEDD2
DNA-binding death effector domain-containing protein 2 |
2 |
5 |
Small-scale |
0.834 | High |
|
|
CASP3
Caspase-3 |
2 |
17 |
Small-scale |
0.783 | High |
|
|
CFLAR
CASP8 and FADD-like apoptosis regulator |
2 |
17 |
Small-scale |
0.757 | High |
|
|
ITCH
E3 ubiquitin-protein ligase Itchy homolog |
8 |
3 |
Small-scale |
0.741 | High |
|
|
BIRC3
Baculoviral IAP repeat-containing protein 3 |
1 |
20 |
Small-scale |
0.724 | High |
|
|
TRAF1
TNF receptor-associated factor 1 |
5 |
18 |
Small-scale |
0.718 | High |
|
|
TNR6
Tumor necrosis factor receptor superfamily member 6 |
6 |
16 |
Small-scale |
0.717 | High |
|
|
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 |
5 |
8 |
Small-scale |
0.714 | High |
|
|
TNF10
Tumor necrosis factor ligand superfamily member 10 |
6 |
13 |
Small-scale |
0.714 | High |
|
|
TR10B
Tumor necrosis factor receptor superfamily member 10B |
5 |
16 |
Small-scale |
0.702 | High |
|
|
TR10A
Tumor necrosis factor receptor superfamily member 10A |
5 |
16 |
Small-scale |
0.699 | High |
|
|
MIB2
E3 ubiquitin-protein ligase MIB2 |
1 |
0 |
Small-scale |
0.687 | High |
|
|
TRAF2
TNF receptor-associated factor 2 |
4 |
20 |
Small-scale |
0.676 | High |
|
|
PLIN5
Perilipin-5 |
3 |
2 |
High-throughput |
0.667 | High |
|
|
M3K14
Mitogen-activated protein kinase kinase kinase 14 |
1 |
7 |
Small-scale |
0.665 | High |
|
|
UBP8
Ubiquitin carboxyl-terminal hydrolase 8 |
2 |
4 |
Small-scale |
0.634 | High |
|
|
MP2K7
Dual specificity mitogen-activated protein kinase kinase 7 |
1 |
9 |
Small-scale |
0.618 | High |
|
|
NFKB1
Nuclear factor NF-kappa-B p105 subunit |
1 |
4 |
Small-scale |
0.618 | High |
|
|
MP2K4
Dual specificity mitogen-activated protein kinase kinase 4 |
1 |
12 |
Small-scale |
0.618 | High |
|
|
MP2K1
Dual specificity mitogen-activated protein kinase kinase 1 |
1 |
11 |
Small-scale |
0.618 | High |
|
|
M3K5
Mitogen-activated protein kinase kinase kinase 5 |
1 |
6 |
Small-scale |
0.618 | High |
|
|
P53
Cellular tumor antigen p53 |
2 |
5 |
Small-scale |
0.584 | High |
|
|
CHIP
E3 ubiquitin-protein ligase CHIP |
2 |
3 |
Small-scale |
0.584 | High |
|
|
RNF8
E3 ubiquitin-protein ligase RNF8 |
1 |
5 |
Small-scale |
0.561 | High |
|
|
NEUL3
E3 ubiquitin-protein ligase NEURL3 |
1 |
9 |
Small-scale |
0.561 | High |
|
|
TRI31
E3 ubiquitin-protein ligase TRIM31 |
1 |
9 |
Small-scale |
0.561 | High |
|
|
RNF12
E3 ubiquitin-protein ligase RLIM |
1 |
3 |
Small-scale |
0.561 | High |
|
|
SMAD3
Mothers against decapentaplegic homolog 3 |
1 |
1 |
High-throughput |
0.541 | High |
|
|
MEX3B
RNA-binding protein MEX3B |
1 |
0 |
Small-scale |
0.537 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
1 |
2 |
Small-scale |
0.527 | High |
|
|
CUL1
Cullin-1 |
1 |
5 |
Small-scale |
0.527 | High |
|
|
RIPK2
Receptor-interacting serine/threonine-protein kinase 2 |
1 |
7 |
Small-scale |
0.515 | High |
|
|
DOK2
Docking protein 2 |
1 |
3 |
High-throughput |
0.515 | High |
|
|
CBLB
E3 ubiquitin-protein ligase CBL-B |
1 |
1 |
Small-scale |
0.515 | High |
|
|
SF3B3
Splicing factor 3B subunit 3 |
1 |
2 |
High-throughput |
0.515 | High |
|
|
ATG3
Ubiquitin-like-conjugating enzyme ATG3 |
1 |
1 |
Small-scale |
0.515 | High |
|
|
SKP1
S-phase kinase-associated protein 1 |
1 |
0 |
Small-scale |
0.505 | High |
|
|
SPAS1
Spermatogenesis-associated serine-rich protein 1 |
1 |
1 |
High-throughput |
0.494 | High |
|
|
DAXX
Death domain-associated protein 6 |
1 |
0 |
Small-scale |
0.493 | High |
|
|
EIF3F
Eukaryotic translation initiation factor 3 subunit F |
1 |
6 |
High-throughput |
0.479 | High |
|
|
ANM5
Protein arginine N-methyltransferase 5 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
GELS
Gelsolin |
1 |
3 |
Small-scale |
0.479 | High |
|
|
HS90A
Heat shock protein HSP 90-alpha |
1 |
1 |
Small-scale |
0.479 | High |
|
|
RO52
E3 ubiquitin-protein ligase TRIM21 |
1 |
5 |
High-throughput |
0.479 | High |
|
|
ERBB3
Receptor tyrosine-protein kinase erbB-3 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
NSF
Vesicle-fusing ATPase |
1 |
4 |
High-throughput |
0.479 | High |
|
|
TNFL6
Tumor necrosis factor ligand superfamily member 6 |
1 |
13 |
Small-scale |
0.479 | High |
|
|
EPIPL
Epiplakin |
1 |
1 |
High-throughput |
0.479 | High |
|
|
B2CL1
Bcl-2-like protein 1 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
EP300
Histone acetyltransferase p300 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
TRAF3
TNF receptor-associated factor 3 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
Q15156
Protein PML |
1 |
5 |
Small-scale |
0.479 | High |
|
|
TCAM1
TIR domain-containing adapter molecule 1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
RNF31
E3 ubiquitin-protein ligase RNF31 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
ANM1
Protein arginine N-methyltransferase 1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
ZBP1
Z-DNA-binding protein 1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
UBP40
Ubiquitin carboxyl-terminal hydrolase 40 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
FKBPL
FK506-binding protein-like |
1 |
1 |
High-throughput |
0.479 | High |
|
|
NOD1
Nucleotide-binding oligomerization domain-containing protein 1 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
UBP15
Ubiquitin carboxyl-terminal hydrolase 15 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
GMEB1
Glucocorticoid modulatory element-binding protein 1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
XRCC6
X-ray repair cross-complementing protein 6 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
MIF
Macrophage migration inhibitory factor |
1 |
0 |
High-throughput |
0.458 | High |
|
|
HNRPL
Heterogeneous nuclear ribonucleoprotein L |
1 |
0 |
High-throughput |
0.458 | High |
|
|
RS29
Small ribosomal subunit protein uS14 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
PSMD2
26S proteasome non-ATPase regulatory subunit 2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CDC37
Hsp90 co-chaperone Cdc37 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
FSCN1
Fascin |
1 |
0 |
High-throughput |
0.458 | High |
|
|
DTX1
E3 ubiquitin-protein ligase DTX1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
NUDC3
NudC domain-containing protein 3 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
STALP
AMSH-like protease |
1 |
0 |
Small-scale |
0.458 | High |
|
|
AASD1
Alanyl-tRNA editing protein Aarsd1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CYBP
Calcyclin-binding protein |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CD3Z
T-cell surface glycoprotein CD3 zeta chain |
1 |
1 |
High-throughput |
0.445 | High |
|
|
SF3B1
Splicing factor 3B subunit 1 |
1 |
1 |
High-throughput |
0.437 | High |
|
|
EFTU
Elongation factor Tu, mitochondrial |
1 |
2 |
High-throughput |
0.437 | High |
|
|
Q53FC7
Heat shock 70 kDa protein 6 |
1 |
3 |
High-throughput |
0.437 | High |
|
|
Q6PK50
HSP90AB1 protein |
1 |
2 |
High-throughput |
0.437 | High |
|
|
Q96BE0
Heat shock cognate 71 kDa protein |
1 |
4 |
High-throughput |
0.437 | High |
|
|
Q9BPW0
Serine/threonine-protein phosphatase |
1 |
4 |
High-throughput |
0.437 | High |
|
|
RBX1
E3 ubiquitin-protein ligase RBX1 |
1 |
3 |
Small-scale |
0.408 | High |
|
|
SEP11
Septin-11 |
3 |
0 |
High-throughput |
0.334 | High |
|
|
B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
FBRL
rRNA 2'-O-methyltransferase fibrillarin |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
BCL6
B-cell lymphoma 6 protein |
1 |
0 |
Small-scale |
0.249 | Low |
|
|
RADIL
Ras-associating and dilute domain-containing protein |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
TM9S2
Transmembrane 9 superfamily member 2 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
SUN2
SUN domain-containing protein 2 |
1 |
0 |
High-throughput |
0.249 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
