HitPredict

Interactor 1: UBXN4 (Q92575)
UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2)
Gene: UBXN4

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 16968747
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006986 - response to unfolded protein GO:0036503 - ERAD pathway
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 251
+	Hs
		1267601 UBXN4_HUMAN (1-508): 1.33e-160: 467: 100.00		DERL2_HUMAN (8-249): 5.87e-78: 236: 34.30
+	Hs
		1287162 FAF2_HUMAN (89-394): 5.4e-45: 165: 11.18		DERL1_HUMAN (1-251): 9.26e-89: 264: 100.00
+	Sc
		748979 UBX7_YEAST (172-506): 3.04e-63: 214: 20.49		DFM1_YEAST (3-249): 2.68e-61: 197: 21.66
+	Hs
		1287173 FAF2_HUMAN (89-394): 5.4e-45: 165: 11.18		DERL2_HUMAN (8-249): 5.87e-78: 236: 34.30
+	Hs
		116707 UBXN8_HUMAN (203-398): 1.28e-35: 135: 15.82		DERL1_HUMAN (1-251): 9.26e-89: 264: 100.00