HitPredict

Interactor 1: PXDN (Q92626)
Peroxidasin homolog (EC 1.11.2.-) (Melanoma-associated antigen MG50) (Peroxidasin 1) (hsPxd01) (Vascular peroxidase 1) (p53-responsive gene 2 protein) [Cleaved into: PXDN active fragment]
Gene: PXDN

Interactor 2: CLC4A (Q9UMR7)
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367)
Gene: CLEC4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~Lectin_C
Common GO terms	GO:0007155 - cell adhesion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1479 Hs			1 237
+	Hs
		1357318 ROBO1_HUMAN (310-1017): 1.82e-78: 289: 17.50		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1218009 IGDC3_HUMAN (344-997): 3.52e-76: 272: 17.75		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		299599 LRIG2_HUMAN (3-712): 9.31e-62: 233: 16.37		CLC4E_HUMAN (25-236): 9.51e-58: 184: 34.58
+	Hs
		299573 LRIG2_HUMAN (3-712): 9.31e-62: 233: 16.37		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		299565 LRIG2_HUMAN (3-712): 9.31e-62: 233: 16.37		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		1166673 LRIG3_HUMAN (2-203): 6.4e-33: 141: 25.87		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1100734 LRIG3_HUMAN (2-203): 6.4e-33: 141: 25.87		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		1263883 LRIG1_HUMAN (1-212): 1.61e-24: 113: 21.51		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		1100785 LRIG1_HUMAN (1-212): 1.61e-24: 113: 21.51		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		644626 LRIG1_HUMAN (1-212): 1.61e-24: 113: 21.51		NKG2A_HUMAN (2-233): 1.65e-40: 140: 16.81