HitPredict

Interactor 1: AKAP1 (Q92667)
A-kinase anchor protein 1, mitochondrial (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Protein kinase A-anchoring protein 1) (PRKA1) (Spermatid A-kinase anchor protein 84) (S-AKAP84)
Gene: AKAP1

Interactor 2: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0140374 - antiviral innate immune response
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 903 Hs			1 299
+	Hs
		719031 AKAP1_HUMAN (1-903): 0: 1170: 100.00		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Mm
		139722 AKAP1_MOUSE (1-903): 0: 1148: 67.33		PODO_MOUSE (6-294): 8.11e-75: 235: 15.02
+	Hs
		1305316 TDRKH_HUMAN (603-901): 4.28e-65: 230: 22.05		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Dr
		1123205 TDRD1_DANRE (581-888): 4.49e-25: 114: 14.97		Q6PC13_DANRE (3-291): 7.82e-99: 294: 79.59