HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: H2A1H (Q96KK5)
Histone H2A type 1-H (H2A-clustered histone 12) (Histone H2A/s)
Gene: H2AC12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21951318
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 128
+	Hs
		470485 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		H2A1_HUMAN (1-128): 6.72e-67: 199: 100.00
+	Hs
		555566 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		H2AX_HUMAN (1-124): 2.04e-63: 191: 94.36
+	Hs
		370295 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		H2A1J_HUMAN (1-128): 2.71e-67: 200: 99.22
+	Hs
		369709 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		H2A2C_HUMAN (1-124): 8.56e-65: 194: 98.39
+	Hs
		368928 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		H2AX_HUMAN (1-124): 2.04e-63: 191: 94.36
+	Hs
		377640 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		H2A1J_HUMAN (1-128): 2.71e-67: 200: 99.22
+	Hs
		488005 RARA_HUMAN (52-505): 3.54e-105: 324: 23.74		H2A1C_HUMAN (1-128): 6.95e-67: 199: 98.44
+	Hs
		488015 RARA_HUMAN (52-505): 3.54e-105: 324: 23.74		H2A1A_HUMAN (1-125): 1.51e-66: 199: 95.20
+	Hs
		487991 RARA_HUMAN (52-505): 3.54e-105: 324: 23.74		H2A2B_HUMAN (1-128): 1.07e-65: 196: 95.31
+	Hs
		487729 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		H2AJ_HUMAN (1-124): 1.08e-64: 194: 97.58