HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: UBS3B (Q8TF42)
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)
Gene: UBASH3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 649
+	Hs
		790650 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		UBS3A_HUMAN (12-643): 0: 947: 43.37
+	Hs
		126923 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		UBS3A_HUMAN (12-643): 0: 947: 43.37
+	Hs
		203218 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		166042 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Rn
		192744 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SRBS2_RAT (230-317): 1.19e-22: 105: 26.80
+	Hs
		203241 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH3K1_HUMAN (221-375): 5.02e-29: 124: 25.00
+	Hs
		166055 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		SH3K1_HUMAN (221-375): 5.02e-29: 124: 25.00
+	Hs
		203192 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SRBS2_HUMAN (230-317): 1.4e-22: 105: 27.84
+	Hs
		203191 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		VINEX_HUMAN (229-317): 1e-22: 104: 26.97
+	Hs
		203250 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SRBS1_HUMAN (258-317): 1.89e-18: 92.2: 40.00
+	Hs
		790657 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		126930 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Ce
		104723 Q8MQE6_CAEEL (164-455): 3.55e-41: 159: 27.17		SRBS1_CAEEL (218-316): 6.25e-25: 112: 29.29
+	Ce
		104706 Q17795_CAEEL (1-457): 4.87e-36: 143: 27.14		SRBS1_CAEEL (218-316): 6.25e-25: 112: 29.29
+	Hs
		298960 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		SRBS2_HUMAN (230-317): 1.4e-22: 105: 27.84
+	Hs
		126950 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		SH3K1_HUMAN (221-375): 5.02e-29: 124: 25.00
+	Ce
		666212 Q17795_CAEEL (1-457): 4.87e-36: 143: 27.14		SEM5_CAEEL (154-318): 3.08e-21: 94.9: 17.96
+	Hs
		126890 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		SRBS2_HUMAN (230-317): 1.4e-22: 105: 27.84
+	Hs
		126886 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		VINEX_HUMAN (229-317): 1e-22: 104: 26.97
+	Hs
		126942 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		SH3R1_HUMAN (216-315): 3.02e-18: 91.4: 28.00