HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: PACN1 (Q9BY11)
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)
Gene: PACSIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11082044, 36622335
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 444
+	Hs
		203251 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		PACN1_HUMAN (1-444): 6.15e-95: 294: 100.00
+	Hs
		203262 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		PACN2_HUMAN (1-444): 2.16e-80: 258: 61.32
+	Hs
		203260 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		PACN3_HUMAN (7-444): 2.52e-76: 246: 49.32
+	Hs
		790686 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		PACN1_HUMAN (1-444): 6.15e-95: 294: 100.00
+	Dm
		1361424 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VDI1_DROME (16-442): 4.51e-70: 231: 38.46
+	Mm
		936465 WASP_MOUSE (16-487): 4.45e-46: 170: 39.21		PPIP1_MOUSE (10-444): 6.15e-62: 208: 20.68
+	Hs
		207777 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		PPIP1_HUMAN (10-444): 1.02e-62: 210: 19.77
+	Dm
		1361429 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VZD7_DROME (19-407): 2.85e-35: 140: 11.75
+	Mm
		936466 WASP_MOUSE (16-487): 4.45e-46: 170: 39.21		Q0VBR8_MOUSE (15-302): 7.75e-42: 155: 16.61
+	Hs
		790675 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		CIP4_HUMAN (19-391): 3.5e-42: 159: 15.12
+	Hs
		203228 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		ITSN1_HUMAN (367-442): 5.46e-13: 73.6: 31.58
+	Hs
		166049 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN1_HUMAN (367-442): 5.46e-13: 73.6: 31.58
+	Hs
		242926 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		GAS7_HUMAN (15-302): 1.63e-36: 141: 16.44
+	Hs
		790692 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		BI2L1_HUMAN (123-444): 2.84e-36: 141: 13.94
+	Dm
		112580 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		M9ND00_DROME (266-441): 2.73e-12: 71.1: 20.00
+	Dm
		1361426 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VIF7_DROME (266-441): 4.76e-12: 70.3: 20.00
+	Dm
		112684 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		M9NE16_DROME (217-442): 8.3e-09: 59.7: 13.91
+	Hs
		790676 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		ITSN1_HUMAN (367-442): 5.46e-13: 73.6: 31.58
+	Hs
		790644 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		CRKL_HUMAN (366-444): 7.4e-12: 68: 32.91
+	Hs
		790685 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		FNBP1_HUMAN (224-443): 9.17e-09: 59.7: 13.16