HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 999
+	Hs
		1267724 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		370805 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		714336 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		370116 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320786 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		369085 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		377830 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		377137 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		714036 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		504498 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		564142 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		369084 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		368878 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		369248 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		368938 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		320162 ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		377052 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		487886 RARA_HUMAN (52-505): 3.54e-105: 324: 23.74		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		504003 NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Mm
		509285 RARA_MOUSE (52-508): 5.87e-105: 324: 23.58		HS71B_MOUSE (682-813): 1.49e-28: 124: 15.91