Protein: GGA3
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)

Gene: GGA3
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q9NZ52

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network
GO:0006622 - protein targeting to lysosome
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508737

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

9

20

Small-scale

0.975

High

1144887

RABE1
Rab GTPase-binding effector protein 1

5

7

Small-scale

0.937

High

975282

ARF6
ADP-ribosylation factor 6

6

20

Small-scale

0.935

High

1014971

ARF1
ADP-ribosylation factor 1

4

20

Small-scale

0.891

High

1452993

GGA2
ADP-ribosylation factor-binding protein GGA2

2

17

Small-scale

0.793

High

783434

TRI23
E3 ubiquitin-protein ligase TRIM23

2

20

High-throughput

0.783

High

958825

ARF3
ADP-ribosylation factor 3

2

20

Small-scale

0.754

High

548623

MPRI
Cation-independent mannose-6-phosphate receptor

9

7

Small-scale

0.753

High

1452994

GGA1
ADP-ribosylation factor-binding protein GGA1

1

18

Small-scale

0.699

High

507397

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

Small-scale

0.653

High

225861

AP1G1
AP-1 complex subunit gamma-1

1

14

Small-scale

0.647

High

1026255

CLH1
Clathrin heavy chain 1

1

19

Small-scale

0.647

High

1452990

GGA3
ADP-ribosylation factor-binding protein GGA3

1

18

Small-scale

0.647

High

942358

BACE1
Beta-secretase 1

2

4

Small-scale

0.646

High

1250571

PACS1
Phosphofurin acidic cluster sorting protein 1

2

1

Small-scale

0.634

High

989142

AP2B1
AP-2 complex subunit beta

1

15

High-throughput

0.618

High

1139150

DAZP2
DAZ-associated protein 2

2

3

High-throughput

0.606

High

1386466

PKHB2
Pleckstrin homology domain-containing family B member 2

2

2

High-throughput

0.606

High

1406905

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

3

High-throughput

0.606

High

363941

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.595

High

633871

MPRD
Cation-dependent mannose-6-phosphate receptor

2

2

Small-scale

0.594

High

169772

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

18

Small-scale

0.590

High

296005

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.580

High

1452991

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

3

Small-scale

0.578

High

412714

NTRK1
High affinity nerve growth factor receptor

1

20

Small-scale

0.561

High

833503

PTGDS
Prostaglandin-H2 D-isomerase

1

0

Small-scale

0.554

High

1278582

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

2

High-throughput

0.553

High

1099840

PD2R
Prostaglandin D2 receptor

1

2

Small-scale

0.538

High

1417271

TMM59
Transmembrane protein 59

1

1

High-throughput

0.536

High

1452998

RNF11
RING finger protein 11

2

11

Small-scale

0.516

High

1277534

MON2
Protein MON2 homolog

1

4

Small-scale

0.515

High

612350

ADA2B
Alpha-2B adrenergic receptor

1

5

Small-scale

0.512

High

1407482

TS101
Tumor susceptibility gene 101 protein

1

11

Small-scale

0.508

High

414737

P53
Cellular tumor antigen p53

1

4

High-throughput

0.501

High

773052

MYH9
Myosin-9

1

1

High-throughput

0.501

High

1429867

TOLIP
Toll-interacting protein

1

10

Small-scale

0.501

High

1431598

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

3

Small-scale

0.501

High

189882

STX7
Syntaxin-7

1

11

High-throughput

0.479

High

218869

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

226231

STX6
Syntaxin-6

1

7

High-throughput

0.479

High

317687

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.479

High

327481

ZFPL1
Zinc finger protein-like 1

1

3

High-throughput

0.479

High

431924

ITB1
Integrin beta-1

1

2

Small-scale

0.479

High

464066

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.479

High

465671

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

483236

CLCA
Clathrin light chain A

1

9

High-throughput

0.479

High

483406

CLCB
Clathrin light chain B

1

9

High-throughput

0.479

High

560541

IFM1
Interferon-induced transmembrane protein 1

1

11

High-throughput

0.479

High

604241

CXA1
Gap junction alpha-1 protein

1

8

High-throughput

0.479

High

613474

VINC
Vinculin

1

1

High-throughput

0.479

High

630997

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.479

High

631519

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.479

High

641272

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.479

High

648703

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

855781

CRK
Adapter molecule crk

1

7

Small-scale

0.479

High

861813

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

16

Small-scale

0.479

High

1031569

IFM3
Interferon-induced transmembrane protein 3

1

11

High-throughput

0.479

High

1108222

SQSTM
Sequestosome-1

1

6

High-throughput

0.479

High

1110941

LAPM5
Lysosomal-associated transmembrane protein 5

1

1

Small-scale

0.479

High

1114483

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1233531

LTOR1
Ragulator complex protein LAMTOR1

1

4

High-throughput

0.479

High

1276341

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

1383696

VP33A
Vacuolar protein sorting-associated protein 33A

1

5

High-throughput

0.479

High

1391196

BICD1
Protein bicaudal D homolog 1

1

4

High-throughput

0.479

High

1394629

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

16

Small-scale

0.479

High

1405058

SORT
Sortilin

1

7

Small-scale

0.479

High

1452995

MYO6
Unconventional myosin-VI

1

6

High-throughput

0.479

High

1452996

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.479

High

459773

PROF1
Profilin-1

1

0

High-throughput

0.458

High

556379

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

976617

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

1139038

SNX17
Sorting nexin-17

1

0

Small-scale

0.458

High

477197

ADA2A
Alpha-2A adrenergic receptor

1

5

Small-scale

0.457

High

577506

ETS1
Protein C-ets-1

1

2

High-throughput

0.457

High

842876

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

4

Small-scale

0.457

High

1278327

LRP10
Low-density lipoprotein receptor-related protein 10

1

10

Small-scale

0.457

High

1404084

CYH2
Cytohesin-2

1

1

Small-scale

0.457

High

1452197

STAB1
Stabilin-1

1

4

Small-scale

0.457

High

1336221

RN214
RING finger protein 214

1

2

High-throughput

0.439

High

1359646

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

2

Small-scale

0.439

High

140011

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

2

High-throughput

0.437

High

180079

BET1
BET1 homolog

1

7

High-throughput

0.437

High

472139

MET
Hepatocyte growth factor receptor

1

20

Small-scale

0.437

High

541721

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.437

High

710667

EPHA3
Ephrin type-A receptor 3

1

20

High-throughput

0.437

High

711949

LTK
Leukocyte tyrosine kinase receptor

1

20

High-throughput

0.437

High

931906

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.437

High

1157093

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.437

High

1229112

RNF43
E3 ubiquitin-protein ligase RNF43

1

8

High-throughput

0.437

High

1251966

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.437

High

1255853

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1289667

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.437

High

1293181

TMM17
Transmembrane protein 17

1

4

High-throughput

0.437

High

1323019

CXD3
Gap junction delta-3 protein

1

8

High-throughput

0.437

High

1356332

SMAP2
Stromal membrane-associated protein 2

1

5

High-throughput

0.437

High

1428990

WWTR1
WW domain-containing transcription regulator protein 1

1

18

High-throughput

0.437

High

1452992

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

3

High-throughput

0.437

High

1199723

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

447520

NPM
Nucleophosmin

1

2

High-throughput

0.408

High

1129897

EPN4
Clathrin interactor 1

1

8

Small-scale

0.408

High

1452997

SYNRG
Synergin gamma

1

4

Small-scale

0.408

High

1419713

GTPB4
GTP-binding protein 4

1

2

High-throughput

0.373

High

1253126

ZN497
Zinc finger protein 497

2

0

High-throughput

0.316

High

1385094

UPP
Uracil phosphoribosyltransferase homolog

2

0

High-throughput

0.316

High

552712

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.249

Low

1214590

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.249

Low

1415361

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.249

Low

1400161

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025