HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: PF21B (Q96EK2)
PHD finger protein 21B
Gene: PHF21B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 531
+	Hs
		1270501 HDAC2_HUMAN (1-488): 0: 707: 100.00		KDM5B_HUMAN (79-519): 1.17e-70: 247: 13.09
+	Hs
		666546 HDAC2_HUMAN (1-488): 0: 707: 100.00		KDM5A_HUMAN (79-519): 1.84e-67: 238: 13.58
+	Hs
		782369 HDAC2_HUMAN (1-488): 0: 707: 100.00		KDM5C_HUMAN (78-518): 6.19e-66: 234: 13.45
+	Hs
		170436 HDAC2_HUMAN (1-488): 0: 707: 100.00		TIF1A_HUMAN (5-502): 7.68e-65: 229: 13.45
+	Hs
		1270364 HDAC2_HUMAN (1-488): 0: 707: 100.00		PF21A_HUMAN (41-531): 1.26e-53: 194: 28.84
+	Mm
		56900 HDAC2_MOUSE (1-488): 0: 704: 99.39		CHD5_MOUSE (133-525): 4.09e-48: 182: 15.73
+	Hs
		1255037 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD5_HUMAN (131-525): 1.02e-42: 165: 15.89
+	Hs
		331858 HDAC2_HUMAN (1-488): 0: 707: 100.00		NSD2_HUMAN (87-515): 7.44e-41: 160: 12.72
+	Dm
		1276545 HDAC1_DROME (5-472): 0: 653: 77.92		KDM5_DROME (79-518): 9.72e-56: 204: 13.36
+	Hs
		1059770 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD4_HUMAN (301-481): 3.03e-37: 149: 20.51
+	Hs
		1270523 HDAC2_HUMAN (1-488): 0: 707: 100.00		ZMYD8_HUMAN (250-449): 2.18e-36: 146: 19.00
+	Mm
		936393 HDAC2_MOUSE (1-488): 0: 704: 99.39		Q5DTP7_MOUSE (301-481): 2.11e-37: 149: 20.51
+	Hs
		1018617 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD3_HUMAN (167-481): 8.3e-35: 142: 15.04
+	Dm
		1276536 HDAC1_DROME (5-472): 0: 653: 77.92		Q9VDK5_DROME (94-494): 7.47e-45: 171: 13.79
+	Dm
		332806 HDAC1_DROME (5-472): 0: 653: 77.92		CHDM_DROME (120-525): 3.35e-43: 167: 13.29
+	Dm
		68996 HDAC1_DROME (5-472): 0: 653: 77.92		A8WHL4_DROME (94-494): 2.7e-43: 167: 13.30
+	Hs
		1017332 HDAC2_HUMAN (1-488): 0: 707: 100.00		BPTF_HUMAN (320-396): 2.31e-14: 78.7: 33.77
+	Hs
		217495 HDAC2_HUMAN (1-488): 0: 707: 100.00		AIRE_HUMAN (351-403): 2.6e-14: 77.6: 41.51
+	Hs
		1270388 HDAC2_HUMAN (1-488): 0: 707: 100.00		PHF12_HUMAN (337-405): 5.06e-13: 74.1: 35.62
+	Dm
		1276559 HDAC1_DROME (5-472): 0: 653: 77.92		Q9W410_DROME (162-394): 4.39e-16: 83.7: 16.24