Protein: FXL17
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)

Gene: FXL17, FBXL17
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9UF56

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992366

SKP1
S-phase kinase-associated protein 1

9

20

Small-scale

0.969

High

166579

BACH1
Transcription regulator protein BACH1

7

18

Small-scale

0.962

High

1112763

CUL1
Cullin-1

7

20

Small-scale

0.960

High

1199049

KLH12
Kelch-like protein 12

6

15

Small-scale

0.957

High

1358877

KBTB7
Kelch repeat and BTB domain-containing protein 7

4

20

High-throughput

0.900

High

1459087

KLH20
Kelch-like protein 20

4

15

High-throughput

0.892

High

329116

KLHL2
Kelch-like protein 2

3

16

High-throughput

0.861

High

1289779

ZBT46
Zinc finger and BTB domain-containing protein 46

3

10

High-throughput

0.861

High

1114561

CUL3
Cullin-3

3

20

High-throughput

0.839

High

1405535

ZBT18
Zinc finger and BTB domain-containing protein 18

3

6

Small-scale

0.839

High

1454623

KLHL9
Kelch-like protein 9

3

13

High-throughput

0.839

High

1387856

ZBT10
Zinc finger and BTB domain-containing protein 10

3

7

Small-scale

0.817

High

1121548

KEAP1
Kelch-like ECH-associated protein 1

2

16

Small-scale

0.812

High

74375

ZBT42
Zinc finger and BTB domain-containing protein 42

2

6

High-throughput

0.811

High

1235393

KLH10
Kelch-like protein 10

2

16

High-throughput

0.811

High

1452115

KLH28
Kelch-like protein 28

2

16

High-throughput

0.811

High

1247781

KLH17
Kelch-like protein 17

2

14

High-throughput

0.776

High

1454747

KLH13
Kelch-like protein 13

2

13

High-throughput

0.776

High

1454582

KLH14
Kelch-like protein 14

3

13

High-throughput

0.770

High

1339590

KBTB8
Kelch repeat and BTB domain-containing protein 8

1

20

High-throughput

0.757

High

1312883

KLHL7
Kelch-like protein 7

2

15

Small-scale

0.744

High

1286808

KAISO
Transcriptional regulator Kaiso

2

1

Small-scale

0.737

High

161311

ENC1
Ectoderm-neural cortex protein 1

1

17

High-throughput

0.691

High

1290314

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

17

High-throughput

0.691

High

1434618

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

10

High-throughput

0.691

High

1459082

KLHL3
Kelch-like protein 3

1

16

High-throughput

0.691

High

1459081

FXL17
F-box/LRR-repeat protein 17

1

19

Small-scale

0.647

High

1459086

SUFU
Suppressor of fused homolog

3

0

Small-scale

0.645

High

1047771

NOTC2
Neurogenic locus notch homolog protein 2

1

0

Small-scale

0.586

High

984007

RBX1
E3 ubiquitin-protein ligase RBX1

2

6

Small-scale

0.584

High

1458584

SPAST
Spastin

1

3

Small-scale

0.578

High

176424

ZBTB5
Zinc finger and BTB domain-containing protein 5

1

15

High-throughput

0.575

High

1247815

KLH24
Kelch-like protein 24

1

17

High-throughput

0.575

High

1333284

KLH23
Kelch-like protein 23

1

15

High-throughput

0.575

High

1380424

ABTB1
Ankyrin repeat and BTB/POZ domain-containing protein 1

1

14

High-throughput

0.575

High

1430059

KLH25
Kelch-like protein 25

1

15

High-throughput

0.575

High

1459084

KLH21
Kelch-like protein 21

1

16

High-throughput

0.575

High

1459085

ZBT21
Zinc finger and BTB domain-containing protein 21

1

1

High-throughput

0.575

High

1459091

IPP
Actin-binding protein IPP

1

15

High-throughput

0.575

High

995331

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.552

High

1156659

UAP1
UDP-N-acetylhexosamine pyrophosphorylase

1

0

Small-scale

0.549

High

1459088

SGT1
Protein SGT1 homolog

2

8

High-throughput

0.549

High

1254107

ZBT49
Zinc finger and BTB domain-containing protein 49

1

0

High-throughput

0.546

High

1438133

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

0

High-throughput

0.546

High

1407936

ANM1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.537

High

557507

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.536

High

1417389

STK31
Serine/threonine-protein kinase 31

1

0

Small-scale

0.517

High

94338

D6R9G5
Kelch like family member 2

1

18

High-throughput

0.514

High

1200022

KLH26
Kelch-like protein 26

1

13

High-throughput

0.514

High

1450962

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

19

High-throughput

0.514

High

1352063

MICA1
[F-actin]-monooxygenase MICAL1

1

0

High-throughput

0.513

High

1352279

DCA11
DDB1- and CUL4-associated factor 11

1

0

High-throughput

0.513

High

1272845

DHX32
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

1

1

High-throughput

0.489

High

301993

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

1

Small-scale

0.481

High

593876

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

4

Small-scale

0.481

High

1195502

FIL1L
Filamin A-interacting protein 1-like

1

4

Small-scale

0.481

High

1204418

ACBG2
Long-chain-fatty-acid--CoA ligase ACSBG2

1

1

Small-scale

0.481

High

1213393

CFA58
Cilia- and flagella-associated protein 58

1

4

Small-scale

0.481

High

1215994

KAD9
Adenylate kinase 9

1

1

Small-scale

0.481

High

1416446

PHF7
E3 ubiquitin-protein ligase PHF7

1

1

Small-scale

0.481

High

1458812

ZMYM2
Zinc finger MYM-type protein 2

1

1

Small-scale

0.481

High

159903

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

4

Small-scale

0.479

High

187205

PPM1G
Protein phosphatase 1G

1

2

Small-scale

0.479

High

214055

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

20

Small-scale

0.479

High

1458797

PEF1
Peflin

1

9

Small-scale

0.479

High

1459090

ARI1
E3 ubiquitin-protein ligase ARIH1

1

2

High-throughput

0.479

High

239630

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

Small-scale

0.460

High

429138

7B2
Neuroendocrine protein 7B2

1

0

Small-scale

0.460

High

576925

I23O1
Indoleamine 2,3-dioxygenase 1

1

0

Small-scale

0.460

High

709179

TPP2
Tripeptidyl-peptidase 2

1

0

Small-scale

0.460

High

897096

MAP2
Methionine aminopeptidase 2

1

0

Small-scale

0.460

High

1007374

OLR1
Oxidized low-density lipoprotein receptor 1

1

0

Small-scale

0.460

High

1095359

RLF
Zinc finger protein Rlf

1

0

Small-scale

0.460

High

1134879

PSME4
Proteasome activator complex subunit 4

1

0

Small-scale

0.460

High

1164025

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

0

Small-scale

0.460

High

1429073

ZN350
Zinc finger protein 350

1

0

Small-scale

0.460

High

1435051

TASP1
Threonine aspartase 1

1

0

Small-scale

0.460

High

1447058

IFT46
Intraflagellar transport protein 46 homolog

1

0

Small-scale

0.460

High

1459083

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

0

Small-scale

0.460

High

208580

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.458

High

466710

GLI1
Zinc finger protein GLI1

1

0

Small-scale

0.458

High

1352212

PXYP1
2-phosphoxylose phosphatase 1

1

1

Small-scale

0.439

High

1291261

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.426

High

1459089

UFC1
Ubiquitin-fold modifier-conjugating enzyme 1

1

0

Small-scale

0.288

High

190510

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

425969

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

0

Small-scale

0.251

Low

568521

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

Small-scale

0.251

Low

702053

TMOD1
Tropomodulin-1

1

0

Small-scale

0.251

Low

1131905

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

Small-scale

0.251

Low

1150369

BGH3
Transforming growth factor-beta-induced protein ig-h3

1

0

Small-scale

0.251

Low

1327530

SRBD1
S1 RNA-binding domain-containing protein 1

1

0

Small-scale

0.251

Low

1421297

CCSE1
Serine-rich coiled-coil domain-containing protein 1

1

0

Small-scale

0.251

Low

1429436

T126A
Transmembrane protein 126A

1

0

Small-scale

0.251

Low

1437926

RISC
Retinoid-inducible serine carboxypeptidase

1

0

Small-scale

0.251

Low

1452677

EURL
Protein EURL homolog

1

0

Small-scale

0.251

Low

1417935

K1671
Uncharacterized protein KIAA1671

1

0

Small-scale

0.249

Low

593266

LIPP
Pancreatic triacylglycerol lipase

1

0

High-throughput

0.232

Low

1428947

SC5A7
High affinity choline transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025