HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: MAFB (Q9Y5Q3)
Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)
Gene: MAFB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20581830
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2442 Hs			1 323
+	Hs
		265142 CBP_HUMAN (1-2442): 0: 1104: 100.00		MAF_HUMAN (1-323): 2.7e-77: 242: 49.47
+	Mm
		799595 CBP_MOUSE (1-2442): 0: 1060: 95.22		MAF_MOUSE (1-323): 8.05e-79: 246: 49.60
+	Hs
		1081236 CBP_HUMAN (1-2442): 0: 1104: 100.00		NF2L2_HUMAN (34-322): 5.62e-53: 185: 14.58
+	Hs
		1083920 CBP_HUMAN (1-2442): 0: 1104: 100.00		NFE2_HUMAN (77-322): 2.35e-50: 173: 18.94
+	Mm
		101439 F8VPR5_MOUSE (1-2442): 0: 1077: 95.67		NFE2_MOUSE (63-323): 1.46e-56: 189: 19.30
+	Mm
		101443 F8VPR5_MOUSE (1-2442): 0: 1077: 95.67		NF2L2_MOUSE (95-322): 3.7e-52: 182: 17.45
+	Hs
		402304 CBP_HUMAN (1-2442): 0: 1104: 100.00		JUN_HUMAN (103-309): 4.11e-36: 134: 15.94
+	Hs
		566778 CBP_HUMAN (1-2442): 0: 1104: 100.00		JUNB_HUMAN (113-314): 6.18e-35: 131: 16.75
+	Hs
		238467 CBP_HUMAN (1-2442): 0: 1104: 100.00		MAFK_HUMAN (184-320): 1.94e-35: 127: 50.37
+	Hs
		265135 EP300_HUMAN (1-2426): 0: 874: 55.06		MAF_HUMAN (1-323): 2.7e-77: 242: 49.47
+	Hs
		998764 EP300_HUMAN (1-2426): 0: 874: 55.06		NF2L2_HUMAN (34-322): 5.62e-53: 185: 14.58
+	Hs
		401902 EP300_HUMAN (1-2426): 0: 874: 55.06		JUN_HUMAN (103-309): 4.11e-36: 134: 15.94
+	Hs
		566753 EP300_HUMAN (1-2426): 0: 874: 55.06		JUNB_HUMAN (113-314): 6.18e-35: 131: 16.75
+	Mm
		70887 EP300_MOUSE (1-2426): 0: 867: 53.61		JUN_MOUSE (103-309): 1.78e-36: 135: 15.94
+	Dm
		115979 M9PH39_DROME (480-2357): 0: 829: 35.44		JRA_DROME (32-306): 2.03e-42: 150: 13.94
+	Hs
		170381 TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97		NF2L2_HUMAN (34-322): 5.62e-53: 185: 14.58
+	Hs
		402629 TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83		JUN_HUMAN (103-309): 4.11e-36: 134: 15.94
+	Hs
		401440 BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53		JUN_HUMAN (103-309): 4.11e-36: 134: 15.94
+	Hs
		402033 BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89		JUN_HUMAN (103-309): 4.11e-36: 134: 15.94
+	Hs
		401362 MUC1_HUMAN (1947-2441): 7.35e-18: 93.3: 11.02		JUN_HUMAN (103-309): 4.11e-36: 134: 15.94