Protein: S22AE
Solute carrier family 22 member 14 (Organic cation transporter-like 4) (ORCTL-4)

Gene: S22AE, SLC22A14
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q9Y267

Gene Ontology (top 5):
GO:0005743 - mitochondrial inner membrane
GO:0005886 - plasma membrane
GO:0030317 - flagellated sperm motility
GO:0032217 - riboflavin transmembrane transporter activity
GO:0048240 - sperm capacitation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1393282

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.580

High

1042793

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

6

High-throughput

0.515

High

298833

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

1

High-throughput

0.445

High

299707

ATP5L
ATP synthase F(0) complex subunit g, mitochondrial

1

1

High-throughput

0.445

High

321378

ERLN2
Erlin-2

1

7

High-throughput

0.445

High

380603

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

3

High-throughput

0.445

High

380669

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

5

High-throughput

0.445

High

783060

CXG1
Gap junction gamma-1 protein

1

1

High-throughput

0.445

High

787469

TGFR1
TGF-beta receptor type-1

1

1

High-throughput

0.445

High

870837

GLRB
Glycine receptor subunit beta

1

2

High-throughput

0.445

High

904203

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.445

High

1143821

PON2
Serum paraoxonase/arylesterase 2

1

1

High-throughput

0.445

High

1214929

WLS
Protein wntless homolog

1

5

High-throughput

0.445

High

1237975

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

2

High-throughput

0.445

High

1242473

CNNM4
Metal transporter CNNM4

1

11

High-throughput

0.445

High

1271355

LRC8D
Volume-regulated anion channel subunit LRRC8D

1

2

High-throughput

0.445

High

1337088

CNNM3
Metal transporter CNNM3

1

11

High-throughput

0.445

High

1405072

SORT
Sortilin

1

2

High-throughput

0.445

High

1407227

ABCA3
Phospholipid-transporting ATPase ABCA3

1

1

High-throughput

0.445

High

1433158

FZD8
Frizzled-8

1

3

High-throughput

0.445

High

1436439

CNNM2
Metal transporter CNNM2

1

11

High-throughput

0.445

High

1448878

CNNM1
Metal transporter CNNM1

1

11

High-throughput

0.445

High

665751

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.426

High

906954

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.426

High

939838

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

High-throughput

0.426

High

1110826

PKD2
Polycystin-2

1

0

High-throughput

0.426

High

1270559

MARK2
Serine/threonine-protein kinase MARK2

1

0

High-throughput

0.426

High

1293315

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

High-throughput

0.426

High

171025

CLGN
Calmegin

1

9

High-throughput

0.407

High

568112

DOB
HLA class II histocompatibility antigen, DO beta chain

1

4

High-throughput

0.407

High

681083

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.407

High

699265

CALX
Calnexin

1

9

High-throughput

0.407

High

903830

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.407

High

935315

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.407

High

1105592

OS9
Protein OS-9

1

7

High-throughput

0.407

High

1150617

TRAM1
Translocating chain-associated membrane protein 1

1

7

High-throughput

0.407

High

1273303

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

4

High-throughput

0.407

High

1287474

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

11

High-throughput

0.407

High

1291717

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

1

High-throughput

0.407

High

1330443

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.407

High

1333861

TTC13
Tetratricopeptide repeat protein 13

1

5

High-throughput

0.407

High

1347673

NPL4
Nuclear protein localization protein 4 homolog

1

2

High-throughput

0.407

High

1352557

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.407

High

1386417

FAF2
FAS-associated factor 2

1

2

High-throughput

0.407

High

1388125

ERLEC
Endoplasmic reticulum lectin 1

1

7

High-throughput

0.407

High

1394418

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

1

High-throughput

0.407

High

1395683

TM87B
Transmembrane protein 87B

1

2

High-throughput

0.407

High

1432781

TMX1
Thioredoxin-related transmembrane protein 1

1

6

High-throughput

0.407

High

1439537

AT131
Endoplasmic reticulum transmembrane helix translocase

1

8

High-throughput

0.407

High

1439668

TM9S3
Transmembrane 9 superfamily member 3

1

5

High-throughput

0.407

High

1452813

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

5

High-throughput

0.407

High

1458694

DJB11
DnaJ homolog subfamily B member 11

1

3

High-throughput

0.407

High

1458736

FA8A1
Protein FAM8A1

1

5

High-throughput

0.407

High

1458784

SE1L1
Protein sel-1 homolog 1

1

5

High-throughput

0.407

High

1461262

AMFR
E3 ubiquitin-protein ligase AMFR

1

10

High-throughput

0.407

High

956122

SPCS3
Signal peptidase complex subunit 3

2

0

High-throughput

0.305

High

1462337

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.269

Low

551342

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.232

Low

1448332

FBX6
F-box only protein 6

1

0

High-throughput

0.232

Low

1448746

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

0

High-throughput

0.232

Low

1450060

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025