HitPredict

Interactor 1: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Interactor 2: S22A4 (Q9H015)
Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (ETTh) (Organic cation/carnitine transporter 1) (OCTN1)
Gene: SLC22A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31871319, unassigned3795
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 258 Hs			1 551
+	Hs
		962457 RHOA_HUMAN (51-231): 1.74e-90: 267: 46.41		S22A4_HUMAN (1-551): 5.58e-137: 410: 100.00
+	Hs
		466448 RHOC_HUMAN (51-231): 6.88e-90: 265: 46.96		S22A4_HUMAN (1-551): 5.58e-137: 410: 100.00
+	Hs
		1015761 RHOG_HUMAN (48-233): 3.07e-83: 249: 48.93		S22A4_HUMAN (1-551): 5.58e-137: 410: 100.00
+	Hs
		581276 RAC2_HUMAN (50-233): 1.62e-78: 236: 56.52		S22A4_HUMAN (1-551): 5.58e-137: 410: 100.00
+	Hs
		988688 RAC1_HUMAN (50-234): 2.46e-76: 231: 56.76		S22A4_HUMAN (1-551): 5.58e-137: 410: 100.00
+	Hs
		955566 CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82		S22A4_HUMAN (1-551): 5.58e-137: 410: 100.00
+	Hs
		953661 RAC3_HUMAN (50-223): 1.44e-73: 224: 58.62		S22A4_HUMAN (1-551): 5.58e-137: 410: 100.00