Protein: RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide) (RPB17) (RPB8 homolog) (hRPB8)

Gene: RPAB3, POLR2H
Organism: Homo sapiens
Interactions: 191
UniProt ID: P52434

Gene Ontology (top 5):
GO:0001054 - RNA polymerase I activity
GO:0001055 - RNA polymerase II activity
GO:0001056 - RNA polymerase III activity
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

624822

RPB1
DNA-directed RNA polymerase II subunit RPB1

7

10

Small-scale

0.960

High

317094

RPA1
DNA-directed RNA polymerase I subunit RPA1

5

10

Small-scale

0.922

High

583437

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

4

Small-scale

0.899

High

854280

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

4

3

High-throughput

0.895

High

169817

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

3

4

High-throughput

0.861

High

156005

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

10

Small-scale

0.847

High

854366

RPAP3
RNA polymerase II-associated protein 3

2

0

High-throughput

0.748

High

854289

RPB7
DNA-directed RNA polymerase II subunit RPB7

6

5

Small-scale

0.735

High

854291

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

1

Small-scale

0.696

High

854286

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

3

High-throughput

0.694

High

854401

RPC8
DNA-directed RNA polymerase III subunit RPC8

4

5

High-throughput

0.694

High

676841

RPB2
DNA-directed RNA polymerase II subunit RPB2

4

6

Small-scale

0.689

High

181399

RPB4
DNA-directed RNA polymerase II subunit RPB4

3

1

Small-scale

0.670

High

583674

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

1

Small-scale

0.670

High

854328

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

3

1

High-throughput

0.667

High

854398

RPC10
DNA-directed RNA polymerase III subunit RPC10

3

5

High-throughput

0.667

High

854281

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

3

1

Small-scale

0.660

High

402721

RPC4
DNA-directed RNA polymerase III subunit RPC4

3

1

Small-scale

0.656

High

854379

RPC5
DNA-directed RNA polymerase III subunit RPC5

3

2

High-throughput

0.656

High

854380

RPC2
DNA-directed RNA polymerase III subunit RPC2

3

6

Small-scale

0.650

High

48640

MED19
Mediator of RNA polymerase II transcription subunit 19

3

0

High-throughput

0.638

High

313408

MED26
Mediator of RNA polymerase II transcription subunit 26

3

0

High-throughput

0.638

High

295607

RMP
Unconventional prefoldin RPB5 interactor 1

3

0

Small-scale

0.628

High

854383

PIHD1
PIH1 domain-containing protein 1

3

0

High-throughput

0.628

High

270186

RPC9
DNA-directed RNA polymerase III subunit RPC9

2

1

High-throughput

0.611

High

738830

RPB9
DNA-directed RNA polymerase II subunit RPB9

2

5

High-throughput

0.611

High

854293

TF2B
Transcription initiation factor IIB

2

3

High-throughput

0.611

High

854360

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

High-throughput

0.611

High

854370

RPA2
DNA-directed RNA polymerase I subunit RPA2

2

6

High-throughput

0.611

High

854386

RPA12
DNA-directed RNA polymerase I subunit RPA12

2

5

High-throughput

0.611

High

854396

RUVB2
RuvB-like 2

2

2

High-throughput

0.611

High

854352

BARD1
BRCA1-associated RING domain protein 1

2

0

Small-scale

0.603

High

749262

BRCA1
Breast cancer type 1 susceptibility protein

2

1

Small-scale

0.602

High

854295

ERCC6
DNA excision repair protein ERCC-6

2

1

Small-scale

0.595

High

179587

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

0

High-throughput

0.585

High

854313

INT3
Integrator complex subunit 3

2

0

High-throughput

0.585

High

854355

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.585

High

854390

UXT
Protein UXT

2

0

High-throughput

0.585

High

854393

PFD2
Prefoldin subunit 2

2

0

High-throughput

0.585

High

244152

BRD4
Bromodomain-containing protein 4

2

1

Small-scale

0.584

High

346289

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

484439

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

3

High-throughput

0.575

High

369227

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

854381

MED9
Mediator of RNA polymerase II transcription subunit 9

2

0

High-throughput

0.559

High

175525

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

1

High-throughput

0.536

High

586629

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

854292

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

854300

KGP1
cGMP-dependent protein kinase 1

1

2

High-throughput

0.536

High

854321

SPT6H
Transcription elongation factor SPT6

1

1

High-throughput

0.536

High

854339

TF3B
Transcription factor IIIB 90 kDa subunit

1

3

High-throughput

0.536

High

854348

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

4

High-throughput

0.536

High

854354

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

1

1

High-throughput

0.536

High

854357

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.536

High

854362

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

1

High-throughput

0.536

High

854374

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

4

High-throughput

0.536

High

854397

RUVB1
RuvB-like 1

1

2

High-throughput

0.536

High

854402

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

473896

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

2

0

High-throughput

0.528

High

854342

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

0

Small-scale

0.527

High

146611

SOCS2
Suppressor of cytokine signaling 2

1

1

High-throughput

0.515

High

147498

SOCS6
Suppressor of cytokine signaling 6

1

1

High-throughput

0.515

High

61754

BDP1
Transcription factor TFIIIB component B'' homolog

1

0

High-throughput

0.513

High

206614

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.513

High

452689

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

638244

RBTN2
Rhombotin-2

1

0

High-throughput

0.513

High

791400

HD
Huntingtin

1

0

High-throughput

0.513

High

839469

SPB8
Serpin B8

1

0

High-throughput

0.513

High

853208

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.513

High

854308

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

854322

TRM1L
TRMT1-like protein

1

0

High-throughput

0.513

High

854330

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

854334

STK35
Serine/threonine-protein kinase 35

1

0

High-throughput

0.513

High

854336

NELFB
Negative elongation factor B

1

0

High-throughput

0.513

High

854338

JARD2
Protein Jumonji

1

0

High-throughput

0.513

High

854351

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

854353

EPAS1
Endothelial PAS domain-containing protein 1

1

0

High-throughput

0.513

High

854356

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.513

High

854361

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

1

0

High-throughput

0.513

High

854364

NELFA
Negative elongation factor A

1

0

High-throughput

0.513

High

854376

INT9
Integrator complex subunit 9

1

0

High-throughput

0.513

High

854384

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.513

High

854399

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.513

High

607613

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.493

High

854394

GPN3
GPN-loop GTPase 3

1

3

High-throughput

0.489

High

854279

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

Small-scale

0.480

High

854285

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.480

High

123883

SPT5H
Transcription elongation factor SPT5

1

3

High-throughput

0.479

High

125269

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

214156

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.479

High

225359

MED14
Mediator of RNA polymerase II transcription subunit 14

1

4

High-throughput

0.479

High

246555

MCE1
mRNA-capping enzyme

1

2

High-throughput

0.479

High

270489

MED6
Mediator of RNA polymerase II transcription subunit 6

1

2

High-throughput

0.479

High

294562

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

295511

RECQ5
ATP-dependent DNA helicase Q5

1

1

High-throughput

0.479

High

379153

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

487254

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

534082

T2FB
General transcription factor IIF subunit 2

1

1

High-throughput

0.479

High

742144

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

826248

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

854287

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

854290

H4
Histone H4

1

1

High-throughput

0.479

High

854296

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.479

High

854304

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

854311

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

2

High-throughput

0.479

High

854320

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.479

High

854337

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

854340

MED12
Mediator of RNA polymerase II transcription subunit 12

1

1

High-throughput

0.479

High

854341

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

854349

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

854358

CDK19
Cyclin-dependent kinase 19

1

1

High-throughput

0.479

High

854368

SFR19
Splicing factor, arginine/serine-rich 19

1

1

High-throughput

0.479

High

854372

GPN1
GPN-loop GTPase 1

1

3

High-throughput

0.479

High

854389

DNM3B
DNA

1

1

Small-scale

0.479

High

854392

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.479

High

854403

DNM3A
DNA

1

1

Small-scale

0.479

High

122578

MEN1
Menin

1

0

High-throughput

0.458

High

226929

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

233298

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

304597

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.458

High

316486

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.458

High

324291

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

532444

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

569434

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

624416

CCNC
Cyclin-C

1

0

High-throughput

0.458

High

718645

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

779066

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

798811

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

800971

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

0

High-throughput

0.458

High

823736

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

854283

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

854288

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

854298

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.458

High

854299

CUL3
Cullin-3

1

0

High-throughput

0.458

High

854301

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

854302

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

854303

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

854305

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.458

High

854306

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.458

High

854307

IKBB
NF-kappa-B inhibitor beta

1

0

High-throughput

0.458

High

854309

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

854315

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

854316

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

854317

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

854318

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

854323

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

854325

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.458

High

854329

INT1
Integrator complex subunit 1

1

0

High-throughput

0.458

High

854332

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

854335

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

854343

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

854344

MED30
Mediator of RNA polymerase II transcription subunit 30

1

0

High-throughput

0.458

High

854350

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

854359

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

854363

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.458

High

854367

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

854369

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.458

High

854373

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

854377

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.458

High

854378

INT10
Integrator complex subunit 10

1

0

Small-scale

0.458

High

854385

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.458

High

854391

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

854395

INT6
Integrator complex subunit 6

1

0

High-throughput

0.458

High

854400

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.458

High

854326

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

1

1

High-throughput

0.437

High

854333

RASF8
Ras association domain-containing protein 8

1

1

High-throughput

0.437

High

854387

PHRF1
PHD and RING finger domain-containing protein 1

1

1

High-throughput

0.437

High

484404

RPC22
Protein POLR1D, isoform 2

1

0

High-throughput

0.426

High

854310

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

854327

BAP18
Chromatin complexes subunit BAP18

1

0

High-throughput

0.426

High

854371

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

854347

DAA10
Dynein axonemal assembly factor 10

3

0

High-throughput

0.342

High

854375

PDRG1
p53 and DNA damage-regulated protein 1

2

0

High-throughput

0.318

High

854314

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

2

0

High-throughput

0.305

High

171589

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.279

Low

854388

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.279

Low

639564

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.269

Low

854282

ARSF
Arylsulfatase F

1

0

High-throughput

0.269

Low

239536

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

854284

ELOF1
Transcription elongation factor 1 homolog

1

0

Small-scale

0.249

Low

854297

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

0

High-throughput

0.249

Low

854312

OTUD1
OTU domain-containing protein 1

1

0

High-throughput

0.249

Low

854319

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

854324

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

854331

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.249

Low

854345

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

854365

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

854382

ASND1
Asparagine synthetase domain-containing protein 1

1

0

High-throughput

0.249

Low

112040

ASURF
ASNSD1 upstream open reading frame protein

1

0

High-throughput

0.232

Low

854294

TAGL
Transgelin

1

0

High-throughput

0.232

Low

854346

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024