HitPredict

Interactor 1: DLG3 (Q92796)
Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR)
Gene: DLG3

Interactor 2: NLGN3 (Q9NZ94)
Neuroligin-3 (Gliotactin homolog)
Gene: NLGN3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	9278515
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 817 Hs			1 848
+	Hs
		1231765 DLG3_HUMAN (1-817): 0: 713: 100.00		NLGN1_HUMAN (19-837): 0: 997: 70.56
+	Rn
		1144023 DLG3_RAT (1-817): 0: 689: 95.17		NLGN1_RAT (32-837): 0: 971: 69.60
+	Hs
		1245078 DLG3_HUMAN (1-817): 0: 713: 100.00		NLGN2_HUMAN (42-848): 0: 844: 61.39
+	Rn
		1144051 DLG3_RAT (1-817): 0: 689: 95.17		NLGN2_RAT (42-848): 0: 855: 62.11
+	Hs
		942388 DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25		NLGN3_HUMAN (1-848): 0: 1143: 100.00
+	Mm
		57108 DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25		A2AGI2_MOUSE (1-848): 0: 1128: 98.70
+	Hs
		1077290 DLG2_HUMAN (312-547): 2.24e-16: 86: 21.40		NLGN3_HUMAN (1-848): 0: 1143: 100.00
+	Mm
		1143408 DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25		NLGN3_MOUSE (1-848): 0: 1105: 96.34
+	Hs
		942360 DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25		NLGNX_HUMAN (24-848): 0: 1009: 71.03
+	Hs
		942361 DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25		NLGN1_HUMAN (19-837): 0: 997: 70.56
+	Rn
		677788 DLG4_RAT (50-282): 1.36e-25: 115: 20.50		NLGN1_RAT (32-837): 0: 971: 69.60
+	Hs
		1077282 DLG2_HUMAN (312-547): 2.24e-16: 86: 21.40		NLGN1_HUMAN (19-837): 0: 997: 70.56
+	Rn
		1144025 DLG2_RAT (312-547): 1.37e-16: 86.4: 21.40		NLGN1_RAT (32-837): 0: 971: 69.60
+	Mm
		1143338 DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25		NLGN2_MOUSE (42-848): 0: 857: 62.11
+	Rn
		677789 DLG4_RAT (50-282): 1.36e-25: 115: 20.50		NLGN2_RAT (42-848): 0: 855: 62.11
+	Hs
		942363 DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25		NLGN2_HUMAN (42-848): 0: 844: 61.39
+	Dm
		677696 DLG1_DROME (46-817): 1.89e-166: 509: 49.35		Q7KT70_DROME (44-650): 1.82e-139: 439: 29.05
+	Rn
		1144055 DLG2_RAT (312-547): 1.37e-16: 86.4: 21.40		NLGN2_RAT (42-848): 0: 855: 62.11
+	Hs
		1077283 DLG2_HUMAN (312-547): 2.24e-16: 86: 21.40		NLGN2_HUMAN (42-848): 0: 844: 61.39