Protein: DIC
Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10)

Gene: DIC, SLC25A10
Organism: Homo sapiens
Interactions: 197
UniProt ID: Q9UBX3

Gene Ontology (top 5):
GO:0005310 - dicarboxylic acid transmembrane transporter activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1407121

MDFI
MyoD family inhibitor

5

0

High-throughput

0.698

High

1259546

TBA1A
Tubulin alpha-1A chain

3

10

High-throughput

0.657

High

243195

PRKN
E3 ubiquitin-protein ligase parkin

3

13

High-throughput

0.640

High

538054

HSP7C
Heat shock cognate 71 kDa protein

2

8

High-throughput

0.611

High

914787

RM12
Large ribosomal subunit protein bL12m

2

1

High-throughput

0.611

High

1101198

CLN3
Battenin

2

5

Small-scale

0.611

High

1161247

MK06
Mitogen-activated protein kinase 6

2

14

High-throughput

0.611

High

564501

CFTR
Cystic fibrosis transmembrane conductance regulator

2

7

High-throughput

0.601

High

351741

SG1D1
Secretoglobin family 1D member 1

3

1

High-throughput

0.599

High

370122

CYTS
Cystatin-S

3

7

High-throughput

0.599

High

1429189

LACRT
Extracellular glycoprotein lacritin

3

1

High-throughput

0.599

High

685972

KRA59
Keratin-associated protein 5-9

2

9

High-throughput

0.590

High

1108247

SQSTM
Sequestosome-1

2

5

High-throughput

0.584

High

1452840

RBAK
RB-associated KRAB zinc finger protein

2

0

High-throughput

0.580

High

1277438

NT2NA
Notch homolog 2 N-terminal-like protein A

2

3

High-throughput

0.573

High

373397

MYC
Myc proto-oncogene protein

2

12

Small-scale

0.571

High

397139

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

401647

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

11

High-throughput

0.571

High

436751

KPCB
Protein kinase C beta type

2

14

High-throughput

0.571

High

622483

ELK1
ETS domain-containing protein Elk-1

2

5

High-throughput

0.571

High

1370808

BAD
Bcl2-associated agonist of cell death

2

1

High-throughput

0.571

High

1405253

M3K14
Mitogen-activated protein kinase kinase kinase 14

2

14

High-throughput

0.571

High

286596

SG2A1
Mammaglobin-B

2

3

High-throughput

0.558

High

522796

NR2F6
Nuclear receptor subfamily 2 group F member 6

1

11

High-throughput

0.536

High

533038

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.536

High

554852

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

5

High-throughput

0.536

High

662810

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

2

High-throughput

0.536

High

686733

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

3

High-throughput

0.536

High

724710

MK04
Mitogen-activated protein kinase 4

1

11

High-throughput

0.536

High

725672

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

3

High-throughput

0.536

High

846030

CACP
Carnitine O-acetyltransferase

1

2

High-throughput

0.536

High

905697

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.536

High

931145

HSP72
Heat shock-related 70 kDa protein 2

1

8

High-throughput

0.536

High

1104524

ILK
Scaffold protein ILK

1

6

High-throughput

0.536

High

1123469

ICT1
Large ribosomal subunit protein mL62

1

6

High-throughput

0.536

High

1194768

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

1

1

High-throughput

0.536

High

1206256

PREP
Presequence protease, mitochondrial

1

2

High-throughput

0.536

High

1235424

ACD10
Acyl-CoA dehydrogenase family member 10

1

4

High-throughput

0.536

High

1244597

SYDM
Aspartate--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1337131

HIPK4
Homeodomain-interacting protein kinase 4

1

13

High-throughput

0.536

High

1339915

NEK11
Serine/threonine-protein kinase Nek11

1

13

High-throughput

0.536

High

1341340

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.536

High

1386089

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

1

High-throughput

0.536

High

1394112

SYNM
Asparaginyl-tRNA synthetase

1

1

High-throughput

0.536

High

1401776

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

2

High-throughput

0.536

High

1439207

AGO4
Protein argonaute-4

1

8

High-throughput

0.536

High

1448699

LATS2
Serine/threonine-protein kinase LATS2

1

11

High-throughput

0.536

High

1458529

HDAC6
Protein deacetylase HDAC6

1

9

High-throughput

0.536

High

1458861

SARDH
Sarcosine dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

1157313

PROL4
Proline-rich protein 4

2

1

High-throughput

0.533

High

950713

KR108
Keratin-associated protein 10-8

1

8

High-throughput

0.523

High

1230298

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.523

High

1419101

KRA42
Keratin-associated protein 4-2

1

7

High-throughput

0.523

High

584596

VAV
Proto-oncogene vav

2

9

High-throughput

0.521

High

699224

CALX
Calnexin

2

3

High-throughput

0.521

High

1155867

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.515

High

166707

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.513

High

177614

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.513

High

643256

MUTA
Methylmalonyl-CoA mutase, mitochondrial

1

0

High-throughput

0.513

High

926132

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.513

High

1061364

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.513

High

1122874

TFDP1
Transcription factor Dp-1

1

0

High-throughput

0.513

High

1205744

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

0

High-throughput

0.513

High

1349951

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

1385782

NSUN4
5-cytosine rRNA methyltransferase NSUN4

1

0

High-throughput

0.513

High

1416032

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1417448

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.513

High

1437478

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

1450539

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.513

High

1458863

RUVB1
RuvB-like 1

1

0

High-throughput

0.513

High

411102

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

8

High-throughput

0.500

High

414775

P53
Cellular tumor antigen p53

1

3

High-throughput

0.500

High

1410115

KR412
Keratin-associated protein 4-12

1

7

High-throughput

0.494

High

846801

GRK6
G protein-coupled receptor kinase 6

1

11

High-throughput

0.489

High

1034840

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

4

High-throughput

0.489

High

1286383

NEK8
Serine/threonine-protein kinase Nek8

1

12

High-throughput

0.489

High

1289378

ST32C
Serine/threonine-protein kinase 32C

1

12

High-throughput

0.489

High

1434663

SG196
Protein O-mannose kinase

1

1

High-throughput

0.489

High

1458867

RPKL1
Ribosomal protein S6 kinase-like 1

1

14

High-throughput

0.489

High

125649

LEG9
Galectin-9

1

7

High-throughput

0.479

High

129512

MEN1
Menin

1

1

High-throughput

0.479

High

137837

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

6

High-throughput

0.479

High

275127

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

4

High-throughput

0.479

High

320115

UFL1
E3 UFM1-protein ligase 1

1

5

High-throughput

0.479

High

349279

LATS1
Serine/threonine-protein kinase LATS1

1

5

High-throughput

0.479

High

406758

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.479

High

412751

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.479

High

458509

ADRB2
Beta-2 adrenergic receptor

1

4

High-throughput

0.479

High

471301

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

5

High-throughput

0.479

High

587531

TFE2
Transcription factor E2-alpha

1

1

High-throughput

0.479

High

765968

BMI1
Polycomb complex protein BMI-1

1

8

High-throughput

0.479

High

766919

PHB1
Prohibitin 1

1

14

High-throughput

0.479

High

774686

BASI
Basigin

1

9

High-throughput

0.479

High

800146

COIL
Coilin

1

5

High-throughput

0.479

High

837891

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

High-throughput

0.479

High

872842

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.479

High

879577

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.479

High

883353

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

4

High-throughput

0.479

High

897415

CDK7
Cyclin-dependent kinase 7

1

8

High-throughput

0.479

High

905242

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.479

High

927162

ATX3
Ataxin-3

1

3

Small-scale

0.479

High

941986

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.479

High

962594

RHOA
Transforming protein RhoA

1

10

High-throughput

0.479

High

971236

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.479

High

984006

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

High-throughput

0.479

High

1008923

RED1
Double-stranded RNA-specific editase 1

1

4

High-throughput

0.479

High

1026576

HSF1
Heat shock factor protein 1

1

4

High-throughput

0.479

High

1051074

FAK1
Focal adhesion kinase 1

1

10

High-throughput

0.479

High

1067796

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

1114550

CUL3
Cullin-3

1

14

High-throughput

0.479

High

1121358

TRI14
Tripartite motif-containing protein 14

1

12

High-throughput

0.479

High

1128856

NBR1
Next to BRCA1 gene 1 protein

1

2

High-throughput

0.479

High

1138719

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1152488

T22D1
TSC22 domain family protein 1

1

1

High-throughput

0.479

High

1162604

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

2

High-throughput

0.479

High

1180264

SMU1
WD40 repeat-containing protein SMU1

1

11

High-throughput

0.479

High

1197737

MIDN
Midnolin

1

6

High-throughput

0.479

High

1241830

PRP8
Pre-mRNA-processing-splicing factor 8

1

3

High-throughput

0.479

High

1276910

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

1312439

ASXL1
Polycomb group protein ASXL1

1

6

High-throughput

0.479

High

1316893

ASPM
Abnormal spindle-like microcephaly-associated protein

1

3

High-throughput

0.479

High

1328322

RM50
Large ribosomal subunit protein mL50

1

1

High-throughput

0.479

High

1338415

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1352809

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1366611

AKAP1
A-kinase anchor protein 1, mitochondrial

1

5

High-throughput

0.479

High

1367498

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

1383271

CLUA1
Clusterin-associated protein 1

1

4

High-throughput

0.479

High

1397523

CI072
Guanine nucleotide exchange factor C9orf72

1

6

High-throughput

0.479

High

1401426

CIC
Protein capicua homolog

1

10

High-throughput

0.479

High

1404818

RING2
E3 ubiquitin-protein ligase RING2

1

9

High-throughput

0.479

High

1410156

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

7

High-throughput

0.479

High

1418216

RM09
Large ribosomal subunit protein bL9m

1

1

High-throughput

0.479

High

1418329

RM01
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.479

High

1428402

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

10

High-throughput

0.479

High

1429384

SPRTN
DNA-dependent metalloprotease SPRTN

1

6

High-throughput

0.479

High

1436529

ECT2
Protein ECT2

1

7

High-throughput

0.479

High

1446414

BRD7
Bromodomain-containing protein 7

1

12

High-throughput

0.479

High

1451302

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

1452914

TECR
Very-long-chain enoyl-CoA reductase

1

4

High-throughput

0.479

High

1458860

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1458865

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

3

High-throughput

0.479

High

1458866

MAGD1
Melanoma-associated antigen D1

1

9

High-throughput

0.479

High

155134

SOCS2
Suppressor of cytokine signaling 2

1

9

High-throughput

0.470

High

156090

SOCS6
Suppressor of cytokine signaling 6

1

10

High-throughput

0.470

High

218914

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

956526

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.458

High

1306928

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1314560

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

1380680

FBX32
F-box only protein 32

1

0

Small-scale

0.458

High

1251971

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.457

High

1151

SIM26
Small integral membrane protein 26

1

6

High-throughput

0.445

High

143483

E2F3
Transcription factor E2F3

1

2

Small-scale

0.445

High

423384

A4
Amyloid-beta precursor protein

1

10

Small-scale

0.445

High

626390

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

13

High-throughput

0.445

High

653638

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

1130501

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.445

High

1453271

GRHL1
Grainyhead-like protein 1 homolog

1

6

High-throughput

0.445

High

950028

KR103
Keratin-associated protein 10-3

1

8

High-throughput

0.439

High

164462

NRP1
Neuropilin-1

1

4

High-throughput

0.437

High

291580

NU155
Nuclear pore complex protein Nup155

1

3

High-throughput

0.437

High

294474

CD123
Translation initiation factor eIF2 assembly protein

1

7

High-throughput

0.437

High

299417

FLOT1
Flotillin-1

1

11

High-throughput

0.437

High

353607

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.437

High

437028

K1C18
Keratin, type I cytoskeletal 18

1

4

High-throughput

0.437

High

451457

NFM
Neurofilament medium polypeptide

1

4

High-throughput

0.437

High

576695

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

4

High-throughput

0.437

High

861319

MAP1B
Microtubule-associated protein 1B

1

10

High-throughput

0.437

High

984318

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

8

High-throughput

0.437

High

1126200

GRM2
Metabotropic glutamate receptor 2

1

3

High-throughput

0.437

High

1218366

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

1233548

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1253005

BAKOR
Beclin 1-associated autophagy-related key regulator

1

5

High-throughput

0.437

High

1255944

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1271033

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.437

High

1333898

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

6

Small-scale

0.437

High

1348238

TIP
T-cell immunomodulatory protein

1

4

High-throughput

0.437

High

1370959

TNR14
Tumor necrosis factor receptor superfamily member 14

1

7

High-throughput

0.437

High

1386403

FAF2
FAS-associated factor 2

1

4

High-throughput

0.437

High

1389409

RNF31
E3 ubiquitin-protein ligase RNF31

1

10

High-throughput

0.437

High

1393790

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.437

High

1418825

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

5

High-throughput

0.437

High

1434138

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

1448302

FBX6
F-box only protein 6

1

9

High-throughput

0.437

High

1448847

TMPS4
Transmembrane protease serine 4

1

13

High-throughput

0.437

High

1452385

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

4

High-throughput

0.437

High

1458862

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.437

High

1458864

AAR2
Protein AAR2 homolog

1

5

High-throughput

0.437

High

880884

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.426

High

1445846

S40A1
Ferroportin

1

0

High-throughput

0.426

High

1193273

SV2C
Synaptic vesicle glycoprotein 2C

1

16

High-throughput

0.407

High

1227632

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.407

High

1310974

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

1

High-throughput

0.407

High

1335764

MOT11
Monocarboxylate transporter 11

1

9

High-throughput

0.407

High

1310040

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

180093

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

1399012

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

1412712

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025