HitPredict

Interactor 1: EZH1 (Q92800)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1

Interactor 2: EZH1 (Q92800)
Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.356) (ENX-2) (Enhancer of zeste homolog 1)
Gene: EZH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19026781
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRC2_HTH_1~PRC2_HTH_1, SET~preSET_CXC, SET~SET
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
and 14 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 747
Hs

1 747
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Zm
+ At
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024