Interactor 1: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 12888487, 10545121, 24423233, 10779504, 10490106, 22328728, 10891493, 29301498, 29746960, 19188449
Identification Methods enzymatic study, pull down, x-ray crystallography, affinity chromatography technology, acetylase assay
Interaction Type direct interaction, association, physical association, acetylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Acetyltransf_1~Acetyltransf_1, Bromodomain~Bromodomain, PCAF_N~PCAF_N
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000124 - SAGA complex
GO:0000432 - positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000776 - kinetochore
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
and 60 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 832
Hs

1 832
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Last updated: 15 Jul 2024