Interactor 1: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B
Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 1.00 | 0.978 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12888487, 10545121, 24423233, 10779504, 10490106, 22328728, 10891493, 29301498, 29746960, 19188449 |
Identification Methods | enzymatic study, pull down, x-ray crystallography, affinity chromatography technology, acetylase assay |
Interaction Type | direct interaction, association, physical association, acetylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Acetyltransf_1~Acetyltransf_1, Bromodomain~Bromodomain, PCAF_N~PCAF_N |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000124 - SAGA complex GO:0000432 - positive regulation of transcription from RNA polymerase II promoter by glucose GO:0000776 - kinetochore GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding and 60 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024