Interactor 1: CASPA (Q92851)
Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12]
Gene: CASP10

Interactor 2: C8AP2 (Q9UKL3)
CASP8-associated protein 2 (FLICE-associated huge protein)
Gene: CASP8AP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.43 0.60 0.508

The method score is based on:

Property Details
Experiments 15069192
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 521
Hs

1 1982
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024