Protein: SRSF8
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)

Gene: SRSF8
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9BRL6

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

942906

SRPK2
SRSF protein kinase 2

5

19

High-throughput

0.941

High

834109

CLK3
Dual specificity protein kinase CLK3

5

14

High-throughput

0.927

High

1263302

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

4

7

Small-scale

0.897

High

833957

CLK2
Dual specificity protein kinase CLK2

3

14

High-throughput

0.863

High

442440

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

19

High-throughput

0.861

High

1040399

TRA2A
Transformer-2 protein homolog alpha

3

18

High-throughput

0.861

High

1020321

ELAV2
ELAV-like protein 2

2

16

High-throughput

0.811

High

1302010

SRPK1
SRSF protein kinase 1

1

20

High-throughput

0.790

High

925116

TRA2B
Transformer-2 protein homolog beta

2

19

High-throughput

0.783

High

952100

SRSF3
Serine/arginine-rich splicing factor 3

2

20

High-throughput

0.783

High

1310300

LC7L2
Putative RNA-binding protein Luc7-like 2

4

7

High-throughput

0.695

High

432890

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

20

High-throughput

0.691

High

641913

U2AF2
Splicing factor U2AF 65 kDa subunit

1

20

High-throughput

0.691

High

945332

PRR3
Proline-rich protein 3

1

2

High-throughput

0.691

High

993814

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.691

High

1028792

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.691

High

1029063

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.691

High

1084384

SRSF7
Serine/arginine-rich splicing factor 7

1

20

High-throughput

0.691

High

1268156

LAR4B
La-related protein 4B

1

20

High-throughput

0.691

High

1288621

PABP5
Polyadenylate-binding protein 5

1

19

High-throughput

0.691

High

1310295

PUF60
Poly(U)-binding-splicing factor PUF60

1

18

High-throughput

0.691

High

1310297

RALY
RNA-binding protein Raly

1

12

High-throughput

0.691

High

1310301

RBMX2
RNA-binding motif protein, X-linked 2

1

19

High-throughput

0.691

High

1201633

ZCH18
Zinc finger CCCH domain-containing protein 18

3

14

High-throughput

0.667

High

1251000

SNIP1
Smad nuclear-interacting protein 1

3

1

High-throughput

0.667

High

982436

1433F
14-3-3 protein eta

3

19

High-throughput

0.662

High

127852

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.656

High

817738

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

3

High-throughput

0.628

High

1310280

NXF2
Nuclear RNA export factor 2

2

5

High-throughput

0.628

High

446767

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.621

High

149226

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.618

High

374783

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

12

High-throughput

0.618

High

899557

MGN
Protein mago nashi homolog

1

3

High-throughput

0.618

High

964054

SRSF2
Serine/arginine-rich splicing factor 2

1

16

High-throughput

0.618

High

395598

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.602

High

905054

1433G
14-3-3 protein gamma

2

19

High-throughput

0.601

High

1310286

LUC7L
Putative RNA-binding protein Luc7-like 1

3

7

High-throughput

0.600

High

1152522

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

2

11

High-throughput

0.584

High

887417

KR122
Keratin-associated protein 12-2

2

0

High-throughput

0.580

High

1172876

NKAP1
Uncharacterized protein NKAPD1

2

1

High-throughput

0.574

High

1244076

DOCK8
Dedicator of cytokinesis protein 8

2

2

High-throughput

0.571

High

833805

CLK1
Dual specificity protein kinase CLK1

1

14

High-throughput

0.555

High

256570

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

2

High-throughput

0.536

High

448797

RU1C
U1 small nuclear ribonucleoprotein C

1

4

High-throughput

0.536

High

759798

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

801345

KI67
Proliferation marker protein Ki-67

1

10

High-throughput

0.536

High

848114

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.536

High

899325

RL15
Large ribosomal subunit protein eL15

1

4

High-throughput

0.536

High

927469

1433Z
14-3-3 protein zeta/delta

1

19

High-throughput

0.536

High

944918

RED1
Double-stranded RNA-specific editase 1

1

9

High-throughput

0.536

High

950861

ERH
Enhancer of rudimentary homolog

1

1

High-throughput

0.536

High

1031599

ATM
Serine-protein kinase ATM

1

4

High-throughput

0.536

High

1092894

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

5

High-throughput

0.536

High

1113837

GRDN
Girdin

1

9

High-throughput

0.536

High

1310290

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

5

High-throughput

0.536

High

1310299

TR150
Thyroid hormone receptor-associated protein 3

1

6

High-throughput

0.536

High

1310302

CCDC9
Coiled-coil domain-containing protein 9

1

1

High-throughput

0.536

High

1063590

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.515

High

476286

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

14

High-throughput

0.501

High

180436

MAGB2
Melanoma-associated antigen B2

1

4

High-throughput

0.489

High

300249

PRP6
Pre-mRNA-processing factor 6

1

15

High-throughput

0.481

High

839977

F10A1
Hsc70-interacting protein

1

3

High-throughput

0.481

High

1135217

RBM26
RNA-binding protein 26

1

4

High-throughput

0.481

High

1310279

WDR83
WD repeat domain-containing protein 83

1

11

High-throughput

0.481

High

1310288

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.481

High

1310292

NXF1
Nuclear RNA export factor 1

1

5

High-throughput

0.481

High

210240

PRC1
Protein regulator of cytokinesis 1

1

6

High-throughput

0.479

High

268251

EED
Polycomb protein EED

1

10

High-throughput

0.479

High

309013

KI20A
Kinesin-like protein KIF20A

1

17

High-throughput

0.479

High

684297

1433S
14-3-3 protein sigma

1

20

Small-scale

0.479

High

824323

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

917830

H4
Histone H4

1

5

High-throughput

0.479

High

959640

VIGLN
Vigilin

1

20

High-throughput

0.479

High

969951

KIF23
Kinesin-like protein KIF23

1

13

High-throughput

0.479

High

1119473

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

9

High-throughput

0.479

High

1235626

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

1296881

SNX27
Sorting nexin-27

1

4

High-throughput

0.479

High

1310282

ECT2
Protein ECT2

1

8

High-throughput

0.479

High

1310284

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

2

High-throughput

0.479

High

1310287

ANLN
Anillin

1

5

High-throughput

0.479

High

1310294

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1310298

FBW1A
F-box/WD repeat-containing protein 1A

1

10

High-throughput

0.479

High

1152710

SNR48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

1

0

High-throughput

0.460

High

1239267

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.460

High

1310283

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1310285

NGB
Neuroglobin

1

0

High-throughput

0.458

High

1310289

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

70190

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

11

High-throughput

0.445

High

757738

IF4A3
Eukaryotic initiation factor 4A-III

1

20

High-throughput

0.445

High

1284314

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

11

High-throughput

0.445

High

1310296

DDX41
Probable ATP-dependent RNA helicase DDX41

1

13

High-throughput

0.445

High

887943

CD81
CD81 antigen

1

1

High-throughput

0.437

High

1281780

IGSF8
Immunoglobulin superfamily member 8

1

7

High-throughput

0.437

High

1310281

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.437

High

1310291

I36RA
Interleukin-36 receptor antagonist protein

2

0

High-throughput

0.328

High

850296

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

1310293

ZBT47
Zinc finger and BTB domain-containing protein 47

1

0

High-throughput

0.279

Low

547585

FOLR1
Folate receptor alpha

1

0

High-throughput

0.249

Low

1118

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024