HitPredict

Interactor 1: OSTF1 (Q92882)
Osteoclast-stimulating factor 1
Gene: OSTF1

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 214 Hs			1 1343
+	Hs
		965139 ANK2_HUMAN (7-213): 6.1e-37: 138: 11.84		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		100050 ANK2_MOUSE (7-213): 6.1e-37: 138: 11.84		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		1299772 RAI14_HUMAN (3-209): 5.5e-34: 130: 19.23		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		556720 ANK1_HUMAN (47-213): 2.54e-31: 122: 16.24		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1299786 KDIS_HUMAN (2-205): 3.88e-26: 107: 16.83		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1299752 TANC2_HUMAN (122-213): 8.25e-16: 77.3: 17.90		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		56839 TANC2_MOUSE (122-213): 1.67e-15: 76.6: 17.90		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		1268491 ANS1A_HUMAN (3-113): 1.78e-11: 64.6: 19.82		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		100037 ANS1B_MOUSE (1-129): 1.11e-10: 62.3: 15.27		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		1139206 ANS1A_HUMAN (3-113): 1.78e-11: 64.6: 19.82		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		1139204 ANS1B_HUMAN (1-129): 5.53e-11: 63.4: 15.27		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		1191813 ANS1B_HUMAN (1-129): 5.53e-11: 63.4: 15.27		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		809340 ANR11_HUMAN (51-194): 1.69e-36: 137: 30.56		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		809460 RAI14_HUMAN (3-209): 5.5e-34: 130: 19.23		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		1021395 ANK3_HUMAN (7-213): 1.88e-34: 131: 14.46		IQGA2_HUMAN (216-848): 1.05e-121: 416: 14.05
+	Hs
		883552 RIPK4_HUMAN (51-213): 1.52e-17: 82.3: 19.63		IQGA3_HUMAN (214-824): 5.56e-119: 409: 12.04
+	Hs
		1201452 Q9H4D1_HUMAN (51-213): 2.33e-17: 81.9: 19.63		IQGA3_HUMAN (214-824): 5.56e-119: 409: 12.04
+	Hs
		596390 GRB2_HUMAN (11-66): 5.89e-12: 64.3: 48.21		RASA1_HUMAN (184-715): 8.42e-129: 426: 23.32
+	Hs
		809254 GRB2_HUMAN (11-66): 5.89e-12: 64.3: 48.21		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		598527 TANC2_HUMAN (122-213): 8.25e-16: 77.3: 17.90		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21