Protein: KOG1
Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24) (Regulatory-associated protein of TOR) (Raptor)

Gene: KOG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 236
UniProt ID: P38873

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0001558 - regulation of cell growth
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

806339

RAGAB
GTP-binding protein GTR1

7

6

Small-scale

0.955

High

806326

RAGCD
GTP-binding protein GTR2

3

6

Small-scale

0.857

High

762817

TOR1
Serine/threonine-protein kinase TOR1

18

14

Small-scale

0.763

High

801823

KSP1
Serine/threonine-protein kinase KSP1

5

14

Small-scale

0.723

High

806297

LST8
Target of rapamycin complex subunit LST8

5

19

Small-scale

0.716

High

726144

2AAA
Protein phosphatase PP2A regulatory subunit A

1

9

High-throughput

0.713

High

806379

TCO89
Target of rapamycin complex 1 subunit TCO89

6

0

Small-scale

0.702

High

721928

XPO1
Exportin-1

1

13

High-throughput

0.691

High

806321

PIB2
Glutamine sensor PIB2

5

0

Small-scale

0.682

High

743385

TOR2
Serine/threonine-protein kinase TOR2

4

14

Small-scale

0.680

High

526663

HSP72
Heat shock protein SSA2

4

16

Small-scale

0.669

High

509545

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

14

Small-scale

0.651

High

448531

RHO1
GTP-binding protein RHO1

2

14

Small-scale

0.624

High

806271

KOG1
Target of rapamycin complex 1 subunit KOG1

1

16

High-throughput

0.621

High

805341

UBA4
Adenylyltransferase and sulfurtransferase UBA4

2

1

Small-scale

0.620

High

806304

SCD6
Protein SCD6

2

1

Small-scale

0.619

High

780146

SDS22
Protein phosphatase 1 regulatory subunit SDS22

2

4

Small-scale

0.619

High

806286

IMB4
Importin subunit beta-4

1

5

Small-scale

0.618

High

806295

SA185
SIT4-associating protein SAP185

2

1

High-throughput

0.614

High

806328

DCP2
m7GpppN-mRNA hydrolase

2

0

High-throughput

0.600

High

806355

TAP42
Type 2A phosphatase-associated protein 42

2

0

Small-scale

0.598

High

394545

EF1A
Elongation factor 1-alpha

2

2

Small-scale

0.594

High

590620

HSP26
Heat shock protein 26

2

3

High-throughput

0.594

High

756604

MKS1
Negative regulator of RAS-cAMP pathway

2

0

Small-scale

0.585

High

479682

F16P
Fructose-1,6-bisphosphatase

2

1

Small-scale

0.584

High

481617

HSP73
Heat shock protein SSA3

2

16

High-throughput

0.584

High

544832

SSB1
Ribosome-associated molecular chaperone SSB1

2

17

High-throughput

0.584

High

584362

GCN2
eIF-2-alpha kinase GCN2

1

4

Small-scale

0.578

High

575943

CYPH
Peptidyl-prolyl cis-trans isomerase

2

3

High-throughput

0.571

High

806327

PBP1
PAB1-binding protein 1

2

0

Small-scale

0.559

High

624849

EXO70
Exocyst complex component EXO70

1

2

High-throughput

0.552

High

645406

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.552

High

664286

SSD1
Protein SSD1

1

2

High-throughput

0.552

High

721611

RENT1
ATP-dependent helicase NAM7

1

1

High-throughput

0.552

High

738641

EI2BB
Translation initiation factor eIF2B subunit beta

1

6

High-throughput

0.552

High

760649

WHI3
Protein WHI3

1

1

High-throughput

0.552

High

806274

DHH1
ATP-dependent RNA helicase DHH1

1

10

High-throughput

0.552

High

806288

GMT1
GDP-mannose transporter 1

1

1

High-throughput

0.552

High

806316

MUP1
High-affinity methionine permease

1

1

High-throughput

0.552

High

806319

MTHR2
Methylenetetrahydrofolate reductase 2

1

1

High-throughput

0.552

High

806330

HCH1
Hsp90 co-chaperone HCH1

1

1

High-throughput

0.552

High

806384

CHS5
Chitin biosynthesis protein CHS5

1

1

High-throughput

0.552

High

560696

KIN2
Serine/threonine-protein kinase KIN2

1

8

High-throughput

0.536

High

628063

FKBP
FK506-binding protein 1

1

4

Small-scale

0.536

High

646128

NPR1
Nitrogen permease reactivator protein

1

10

High-throughput

0.536

High

740577

IME2
Meiosis induction protein kinase IME2/SME1

1

7

High-throughput

0.536

High

778893

NNK1
Nitrogen network kinase 1

1

14

High-throughput

0.536

High

806317

SAP4
SIT4-associating protein SAP4

1

1

High-throughput

0.536

High

806323

FMP48
Probable serine/threonine-protein kinase FMP48

1

5

High-throughput

0.536

High

806341

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

6

High-throughput

0.536

High

806294

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

743622

RTG2
Retrograde regulation protein 2

1

0

High-throughput

0.529

High

796509

SLM4
Protein SLM4

1

0

High-throughput

0.529

High

805586

LSM12
Protein LSM12

1

0

High-throughput

0.529

High

806280

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

0

High-throughput

0.529

High

806282

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.529

High

806315

PSP2
Protein PSP2

1

0

High-throughput

0.529

High

806377

AB140
tRNA(Thr)

1

0

High-throughput

0.529

High

806386

NMD4
Nonsense-mediated decay protein 4

1

0

High-throughput

0.529

High

806395

DCP1
mRNA-decapping enzyme subunit 1

1

0

High-throughput

0.529

High

794743

RTG3
Retrograde regulation protein 3

1

0

High-throughput

0.513

High

555310

EI2BD
Translation initiation factor eIF2B subunit delta

1

6

High-throughput

0.504

High

686912

BUB3
Spindle assembly checkpoint protein BUB3

1

18

Small-scale

0.501

High

626726

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.500

High

806309

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.500

High

806392

HSP42
Heat shock protein 42

1

3

High-throughput

0.500

High

806298

MAF1
Repressor of RNA polymerase III transcription MAF1

1

0

Small-scale

0.493

High

154357

YO304
Uncharacterized protein YOR304C-A

1

1

High-throughput

0.481

High

361435

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.481

High

364521

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.481

High

366655

ARGI
Arginase

1

2

High-throughput

0.481

High

400063

PUR1
Amidophosphoribosyltransferase

1

2

High-throughput

0.481

High

438297

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.481

High

469993

FUMH
Fumarate hydratase, mitochondrial

1

3

High-throughput

0.481

High

521091

YEY2
Uncharacterized protein YER152C

1

1

High-throughput

0.481

High

607757

HXKG
Glucokinase-1

1

1

High-throughput

0.481

High

636466

ACE2
Metallothionein expression activator

1

5

High-throughput

0.481

High

654782

URE2
Transcriptional regulator URE2

1

1

High-throughput

0.481

High

668911

ERG6
Sterol 24-C-methyltransferase ERG6

1

3

High-throughput

0.481

High

694133

CDC15
Cell division control protein 15

1

19

High-throughput

0.481

High

727014

HS104
Heat shock protein 104

1

3

High-throughput

0.481

High

733611

PROB
Glutamate 5-kinase

1

2

High-throughput

0.481

High

736485

MDHP
Malate dehydrogenase, peroxisomal

1

4

High-throughput

0.481

High

745295

TMN1
Transmembrane 9 superfamily member 1

1

1

High-throughput

0.481

High

746729

KPR1
Ribose-phosphate pyrophosphokinase 1

1

3

High-throughput

0.481

High

760531

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

20

Small-scale

0.481

High

793074

ATPG
ATP synthase subunit gamma, mitochondrial

1

2

High-throughput

0.481

High

793151

AKL1
Serine/threonine-protein kinase AKL1

1

4

High-throughput

0.481

High

806277

BDH1
(R,R)-butanediol dehydrogenase

1

3

High-throughput

0.481

High

806278

FLC2
Flavin carrier protein 2

1

1

High-throughput

0.481

High

806281

KC13
Casein kinase I homolog 3

1

13

High-throughput

0.481

High

806285

SERA
D-3-phosphoglycerate dehydrogenase 1

1

7

High-throughput

0.481

High

806287

LSM4
LSM complex subunit LSM4

1

3

High-throughput

0.481

High

806292

SER33
D-3-phosphoglycerate dehydrogenase 2

1

7

High-throughput

0.481

High

806303

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.481

High

806308

BNA3
Probable kynurenine--oxoglutarate transaminase BNA3

1

1

High-throughput

0.481

High

806322

IMO32
Probable alcohol acetyltransferase

1

1

High-throughput

0.481

High

806325

YG3A
Uncharacterized protein YGR130C

1

14

High-throughput

0.481

High

806331

CA120
CCR4-NOT transcriptional complex subunit CAF120

1

1

High-throughput

0.481

High

806332

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.481

High

806337

DAK1
Dihydroxyacetone kinase 1

1

1

High-throughput

0.481

High

806347

RT17
Small ribosomal subunit protein uS17m

1

3

High-throughput

0.481

High

806350

GLRX3
Monothiol glutaredoxin-3

1

15

High-throughput

0.481

High

806357

ADH6
NADP-dependent alcohol dehydrogenase 6

1

3

High-throughput

0.481

High

806360

ERP1
Protein ERP1

1

8

High-throughput

0.481

High

806363

SKG3
Protein SKG3

1

1

High-throughput

0.481

High

806376

MCA1
Metacaspase-1

1

1

High-throughput

0.481

High

806389

KPR5
Ribose-phosphate pyrophosphokinase 5

1

3

High-throughput

0.481

High

403505

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

5

Small-scale

0.479

High

518288

IF4A
ATP-dependent RNA helicase eIF4A

1

9

Small-scale

0.479

High

579362

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

644625

MDHC
Malate dehydrogenase, cytoplasmic

1

4

Small-scale

0.479

High

752242

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

806324

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

Small-scale

0.479

High

806342

NOP3
Serine/arginine

1

8

Small-scale

0.479

High

806373

LAM6
Membrane-anchored lipid-binding protein LAM6

1

2

Small-scale

0.479

High

806381

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

806388

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

Small-scale

0.479

High

806390

IQG1
Ras GTPase-activating-like protein IQG1

1

6

Small-scale

0.479

High

806394

LAS17
Proline-rich protein LAS17

1

5

Small-scale

0.479

High

427984

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.460

High

541281

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase

1

0

High-throughput

0.460

High

626568

PNPP
4-nitrophenylphosphatase

1

0

High-throughput

0.460

High

633253

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

High-throughput

0.460

High

652709

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.460

High

664493

SEC14
SEC14 cytosolic factor

1

0

High-throughput

0.460

High

692506

GYS2
Glycogen [starch] synthase isoform 2

1

0

High-throughput

0.460

High

705062

AROC
Chorismate synthase ARO2

1

0

High-throughput

0.460

High

743606

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.460

High

757375

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.460

High

757737

PIN4
RNA-binding protein PIN4

1

0

High-throughput

0.460

High

779181

NDK
Nucleoside diphosphate kinase

1

0

High-throughput

0.460

High

780952

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

782613

TVP38
Golgi apparatus membrane protein TVP38

1

0

High-throughput

0.460

High

790317

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.460

High

805027

SDO1L
Restriction of telomere capping protein 3

1

0

High-throughput

0.460

High

805372

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.460

High

806123

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.460

High

806276

KTD1
Protein-toxin resistance protein KTD1

1

0

High-throughput

0.460

High

806291

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.460

High

806299

EMP47
Protein EMP47

1

0

High-throughput

0.460

High

806300

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.460

High

806307

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.460

High

806311

YJ94
Uncharacterized membrane protein YJR124C

1

0

High-throughput

0.460

High

806314

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.460

High

806320

PNC1
Nicotinamidase

1

0

High-throughput

0.460

High

806329

YN8Z
Uncharacterized vacuolar membrane protein YNR061C

1

0

High-throughput

0.460

High

806333

DUG3
Probable glutamine amidotransferase DUG3

1

0

High-throughput

0.460

High

806338

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.460

High

806340

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.460

High

806348

CTPP2
Lipid-anchored plasma membrane protein CPP2

1

0

High-throughput

0.460

High

806349

MIX17
Mitochondrial intermembrane space cysteine motif-containing protein MIX17

1

0

High-throughput

0.460

High

806354

ICY1
Interacting with cytoskeleton protein 1

1

0

High-throughput

0.460

High

806356

KAR5
Nuclear fusion protein KAR5

1

0

High-throughput

0.460

High

806359

IVY1
Protein IVY1

1

0

High-throughput

0.460

High

806362

KYNU
Kynureninase

1

0

High-throughput

0.460

High

806364

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

1

0

High-throughput

0.460

High

806368

PUN1
Protein PUN1

1

0

High-throughput

0.460

High

806372

SNA4
Protein SNA4

1

0

High-throughput

0.460

High

806374

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.460

High

806378

TIM18
Mitochondrial import inner membrane translocase subunit TIM18

1

0

High-throughput

0.460

High

806382

VPS68
Vacuolar protein sorting-associated protein 68

1

0

High-throughput

0.460

High

806383

YP162
Vacuolar membrane protein YPL162C

1

0

High-throughput

0.460

High

806385

TMS1
Membrane protein TMS1

1

0

High-throughput

0.460

High

806387

FCY1
Cytosine deaminase

1

0

High-throughput

0.460

High

806391

MAM3
Protein MAM3

1

0

High-throughput

0.460

High

806393

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.460

High

678676

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.458

High

701483

ACEA
Isocitrate lyase

1

0

Small-scale

0.458

High

736515

SFP1
Transcription factor SFP1

1

0

Small-scale

0.458

High

806273

POP2
Poly(A) ribonuclease POP2

1

0

Small-scale

0.458

High

806302

ALK1
Serine/threonine-protein kinase Haspin homolog ALK1

1

0

High-throughput

0.458

High

806352

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

806361

PAL1
Protein PAL1

1

0

High-throughput

0.458

High

806371

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

644772

CLH
Clathrin heavy chain

1

3

High-throughput

0.457

High

806375

RTC1
Restriction of telomere capping protein 1

1

17

High-throughput

0.457

High

392716

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

670263

NAP1
Nucleosome assembly protein

1

3

High-throughput

0.445

High

675992

MAS5
Mitochondrial protein import protein MAS5

1

12

High-throughput

0.445

High

737405

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

4

High-throughput

0.445

High

781741

SET3
SET domain-containing protein 3

1

17

High-throughput

0.445

High

806289

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

806312

IML1
Vacuolar membrane-associated protein IML1

1

5

High-throughput

0.445

High

806318

HOS2
Probable histone deacetylase HOS2

1

15

High-throughput

0.445

High

806334

PFD4
Prefoldin subunit 4

1

4

High-throughput

0.445

High

806335

APJ1
J domain-containing protein APJ1

1

13

High-throughput

0.445

High

806346

HOS3
Histone deacetylase HOS3

1

19

High-throughput

0.445

High

478415

EI2BG
Translation initiation factor eIF2B subunit gamma

1

2

High-throughput

0.439

High

598399

TUP1
General transcriptional corepressor TUP1

1

19

High-throughput

0.439

High

615014

GLN3
Nitrogen regulatory protein GLN3

1

6

High-throughput

0.439

High

736972

CDC3
Cell division control protein 3

1

10

High-throughput

0.439

High

743864

YEF3
Uncharacterized protein YEL043W

1

1

High-throughput

0.439

High

806272

SKN7
Transcription factor SKN7

1

6

High-throughput

0.439

High

806296

MAD1
Spindle assembly checkpoint component MAD1

1

15

High-throughput

0.439

High

806343

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

1

2

High-throughput

0.439

High

806344

CENPP
Inner kinetochore subunit CTF19

1

1

High-throughput

0.439

High

806380

FLC1
Flavin carrier protein 1

1

1

High-throughput

0.439

High

548203

BIK1
Nuclear fusion protein BIK1

1

8

Small-scale

0.437

High

557705

SRS2
ATP-dependent DNA helicase SRS2

1

1

High-throughput

0.437

High

661514

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.437

High

707060

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

734333

DGR2
2-deoxy-glucose resistant protein 2

1

17

High-throughput

0.437

High

806283

BIM1
Protein BIM1

1

5

Small-scale

0.437

High

806293

MPH1
ATP-dependent DNA helicase MPH1

1

9

High-throughput

0.437

High

806336

EF3B
Elongation factor 3B

1

2

Small-scale

0.437

High

794703

SEA4
SEH-associated protein 4

1

0

High-throughput

0.426

High

806275

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

793856

SWD3
COMPASS component SWD3

1

18

High-throughput

0.407

High

805539

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

14

High-throughput

0.407

High

806305

STU2
Protein STU2

1

3

High-throughput

0.407

High

806370

BRE1
E3 ubiquitin-protein ligase BRE1

1

17

High-throughput

0.407

High

806345

LGE1
Transcriptional regulatory protein LGE1

3

0

High-throughput

0.330

High

534183

PCKA
Phosphoenolpyruvate carboxykinase

2

0

Small-scale

0.306

High

740261

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.288

High

734800

VPH2
Vacuolar ATPase assembly integral membrane protein VPH2

1

0

High-throughput

0.279

Low

515021

MTCU2
Copper metallothionein 1-2

1

0

High-throughput

0.251

Low

571831

SNA3
Protein SNA3

1

0

High-throughput

0.251

Low

780745

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.251

Low

806279

HPH2
Protein HPH2

1

0

High-throughput

0.251

Low

806284

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

806290

PEX17
Peroxisomal membrane protein PEX17

1

0

High-throughput

0.251

Low

806301

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.251

Low

806306

STB2
Protein STB2

1

0

High-throughput

0.251

Low

806310

VPS55
Vacuolar protein sorting-associated protein 55

1

0

High-throughput

0.251

Low

806313

ECL1
Extender of the chronological lifespan protein 1

1

0

High-throughput

0.251

Low

806351

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.251

Low

806358

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

806365

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

806366

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.251

Low

806367

YP084
Uncharacterized protein YPR084W

1

0

High-throughput

0.251

Low

806369

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.251

Low

806396

ISN1
IMP-specific 5'-nucleotidase 1

1

0

High-throughput

0.251

Low

806353

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

736645

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025