Interactor 1: UFD1 (Q92890)
Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1)
Gene: UFD1

Interactor 2: FAF2 (Q96CS3)
FAS-associated factor 2 (UBX domain-containing protein 3B) (UBX domain-containing protein 8)
Gene: FAF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 26389662, 18775313
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0030970 - retrograde protein transport, ER to cytosol
GO:0034098 - VCP-NPL4-UFD1 AAA ATPase complex
GO:0036503 - ERAD pathway
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 307
Hs

1 445
+ Hs
+ Xl
+ Hs
+ Xl
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024