Protein: CYFP2
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)

Gene: CYFP2, CYFIP2
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q96F07

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1390228

NCKP1
Nck-associated protein 1

5

6

Small-scale

0.919

High

1316694

ABI1
Abl interactor 1

3

10

Small-scale

0.817

High

1390217

ABI2
Abl interactor 2

2

12

High-throughput

0.811

High

1390226

WASF3
Actin-binding protein WASF3

2

13

High-throughput

0.811

High

1390230

WASF2
Actin-binding protein WASF2

2

12

Small-scale

0.789

High

1390221

ABI3
ABI gene family member 3

2

14

Small-scale

0.737

High

1364460

WASF1
Actin-binding protein WASF1

1

12

High-throughput

0.691

High

222173

NCK2
Cytoplasmic protein NCK2

4

12

High-throughput

0.691

High

1332962

ZN511
Zinc finger protein 511

3

1

High-throughput

0.667

High

1389781

DTBP1
Dysbindin

3

1

High-throughput

0.667

High

1390227

BAIP2
BAR/IMD domain-containing adapter protein 2

3

9

High-throughput

0.667

High

1390208

HSPB9
Heat shock protein beta-9

3

0

High-throughput

0.638

High

257158

CCD22
Coiled-coil domain-containing protein 22

2

1

High-throughput

0.628

High

1390215

HOME3
Homer protein homolog 3

2

3

High-throughput

0.628

High

1056899

FMR1
Fragile X messenger ribonucleoprotein 1

2

9

Small-scale

0.619

High

581226

RAC2
Ras-related C3 botulinum toxin substrate 2

1

17

High-throughput

0.618

High

953612

RAC3
Ras-related C3 botulinum toxin substrate 3

1

17

High-throughput

0.618

High

962370

RHOA
Transforming protein RhoA

1

16

High-throughput

0.618

High

988603

RAC1
Ras-related C3 botulinum toxin substrate 1

1

17

High-throughput

0.618

High

1015676

RHOG
Rho-related GTP-binding protein RhoG

1

14

High-throughput

0.618

High

1379928

LHX4
LIM/homeobox protein Lhx4

2

2

High-throughput

0.611

High

1049655

1433F
14-3-3 protein eta

2

6

High-throughput

0.601

High

1352124

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

2

13

High-throughput

0.601

High

1357193

BRK1
Protein BRICK1

2

3

High-throughput

0.601

High

1390207

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

2

High-throughput

0.601

High

346180

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.584

High

537697

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.584

High

1192203

AMZ1
Archaemetzincin-1

2

1

High-throughput

0.574

High

1390224

CBLC
E3 ubiquitin-protein ligase CBL-C

2

1

High-throughput

0.574

High

396693

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

1107103

BIRC3
Baculoviral IAP repeat-containing protein 3

2

0

High-throughput

0.561

High

1238070

CGB2
Choriogonadotropin subunit beta variant 2

2

1

High-throughput

0.552

High

162023

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

1

High-throughput

0.536

High

212033

M3K13
Mitogen-activated protein kinase kinase kinase 13

1

5

High-throughput

0.536

High

251796

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

6

High-throughput

0.536

High

594077

NCK1
SH2/SH3 adapter protein NCK1

1

13

High-throughput

0.536

High

730137

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.536

High

990593

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.536

High

993289

ACTG
Actin, cytoplasmic 2

1

5

High-throughput

0.536

High

1258668

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

1

High-throughput

0.536

High

1311209

RHG12
Rho GTPase-activating protein 12

1

4

High-throughput

0.536

High

1347834

RIN3
Ras and Rab interactor 3

1

2

High-throughput

0.536

High

258390

GAS7
Growth arrest-specific protein 7

1

4

High-throughput

0.527

High

1106649

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.518

High

50660

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.513

High

71237

HIDE1
Protein HIDE1

1

0

High-throughput

0.513

High

182720

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.513

High

231000

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.513

High

587179

ITF2
Transcription factor 4

1

0

High-throughput

0.513

High

618409

TSN8
Tetraspanin-8

1

0

High-throughput

0.513

High

867335

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

1273268

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

1291654

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1325894

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1338751

ARI1B
AT-rich interactive domain-containing protein 1B

1

0

High-throughput

0.513

High

1363202

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1390204

SPTCS
Spatacsin

1

0

High-throughput

0.513

High

1390213

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

1390216

FGOP2
FGFR1 oncogene partner 2

1

0

High-throughput

0.513

High

900087

FXR1
RNA-binding protein FXR1

1

9

Small-scale

0.508

High

127162

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.501

High

163818

TCRG1
Transcription elongation regulator 1

1

5

High-throughput

0.501

High

280773

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.501

High

733045

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

835359

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

2

High-throughput

0.489

High

1192081

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

2

High-throughput

0.489

High

1390219

NHSL3
NHS-like protein 3

1

4

High-throughput

0.489

High

363704

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

406492

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

412422

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

463192

YES
Tyrosine-protein kinase Yes

1

9

High-throughput

0.479

High

463701

LYN
Tyrosine-protein kinase Lyn

1

8

High-throughput

0.479

High

540619

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

541635

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.479

High

557427

SRC
Proto-oncogene tyrosine-protein kinase Src

1

8

High-throughput

0.479

High

582918

EZRI
Ezrin

1

4

High-throughput

0.479

High

589395

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

648626

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.479

High

658976

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

1

High-throughput

0.479

High

696194

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

710878

EPHB2
Ephrin type-B receptor 2

1

9

High-throughput

0.479

High

840891

TEC
Tyrosine-protein kinase Tec

1

8

High-throughput

0.479

High

896609

VASP
Vasodilator-stimulated phosphoprotein

1

4

High-throughput

0.479

High

920183

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.479

High

932113

EPHA4
Ephrin type-A receptor 4

1

9

High-throughput

0.479

High

970910

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

987855

GRB2
Growth factor receptor-bound protein 2

1

10

High-throughput

0.479

High

995760

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.479

High

1004957

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1143230

PLEC
Plectin

1

5

High-throughput

0.479

High

1147405

EPHA7
Ephrin type-A receptor 7

1

7

High-throughput

0.479

High

1157027

NTRK3
NT-3 growth factor receptor

1

8

High-throughput

0.479

High

1211755

UBX11
UBX domain-containing protein 11

1

1

High-throughput

0.479

High

1227241

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.479

High

1255029

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1295529

MIB1
E3 ubiquitin-protein ligase MIB1

1

2

High-throughput

0.479

High

1313329

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1364515

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

1366999

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1370284

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.479

High

1390206

MARK4
MAP/microtubule affinity-regulating kinase 4

1

1

High-throughput

0.479

High

1390209

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

5

Small-scale

0.479

High

1390210

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1390212

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1390218

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

1390222

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1390223

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

5

Small-scale

0.479

High

1390225

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

4

Small-scale

0.479

High

1390231

MYO16
Unconventional myosin-XVI

1

3

Small-scale

0.479

High

366366

PLMN
Plasminogen

1

0

High-throughput

0.460

High

1203984

ZC12A
Endoribonuclease ZC3H12A

1

0

High-throughput

0.460

High

180013

BET1
BET1 homolog

1

0

High-throughput

0.458

High

320751

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

418348

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

472973

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

1194733

FBX43
F-box only protein 43

1

0

Small-scale

0.458

High

1251263

DNMBP
Dynamin-binding protein

1

0

Small-scale

0.458

High

1390229

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.458

High

900456

FXR2
RNA-binding protein FXR2

1

9

Small-scale

0.457

High

62574

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.445

High

530209

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

1110529

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

5

High-throughput

0.445

High

1209502

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

1325303

PALS1
Protein PALS1

1

3

High-throughput

0.445

High

1390214

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

106446

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

218616

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

276163

NIPS2
Protein NipSnap homolog 2

1

1

Small-scale

0.437

High

640259

EPHA1
Ephrin type-A receptor 1

1

7

High-throughput

0.437

High

710423

EPHA2
Ephrin type-A receptor 2

1

9

High-throughput

0.437

High

768873

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

845754

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.437

High

1034316

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

10

High-throughput

0.437

High

1256815

NYAP1
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1

1

10

Small-scale

0.437

High

1390220

NYAP2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

1

9

Small-scale

0.437

High

380117

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

397974

ANGI
Angiogenin

1

0

High-throughput

0.426

High

934992

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

1235273

NCLX
Mitochondrial sodium/calcium exchanger protein

1

0

High-throughput

0.426

High

1251171

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.426

High

1292278

S2611
Sodium-independent sulfate anion transporter

1

0

High-throughput

0.426

High

1330787

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.426

High

1205204

NHSL2
NHS-like protein 2

1

2

High-throughput

0.407

High

720723

OXYR
Oxytocin receptor

1

0

High-throughput

0.282

High

718448

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1291863

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

0

High-throughput

0.279

Low

1350856

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1390205

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

353491

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.269

Low

653501

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

1390211

S6A16
Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025