HitPredict

Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Interactor 2: KLDC3 (Q9BQ90)
Kelch domain-containing protein 3 (Testis intracellular mediator protein)
Gene: KLHDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 382
+	Hs
		299528 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH18_HUMAN (3-247): 6.9e-42: 156: 16.33
+	Hs
		1120793 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH12_HUMAN (1-191): 4.3e-40: 151: 18.33
+	Hs
		1272664 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH13_HUMAN (140-381): 1.58e-39: 150: 15.39
+	Hs
		1153787 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH10_HUMAN (2-190): 6.04e-33: 131: 17.46
+	Hs
		1272662 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLHL9_HUMAN (1-188): 2.78e-31: 127: 14.58
+	Hs
		1272661 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLHL8_HUMAN (1-136): 8.04e-20: 93.2: 19.12
+	Hs
		276945 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		ATRN_HUMAN (4-108): 2.39e-09: 61.2: 23.85