Protein: NOD1
Nucleotide-binding oligomerization domain-containing protein 1 (hNod1) (Caspase recruitment domain-containing protein 4)

Gene: NOD1
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q9Y239

Gene Ontology (top 5):
GO:0002221 - pattern recognition receptor signaling pathway
GO:0002606 - positive regulation of dendritic cell antigen processing and presentation
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

214470

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

7

10

Small-scale

0.956

High

1490475

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

3

16

Small-scale

0.861

High

1380416

RNF34
E3 ubiquitin-protein ligase RNF34

1

5

Small-scale

0.740

High

1022810

XIAP
E3 ubiquitin-protein ligase XIAP

1

9

Small-scale

0.734

High

508851

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

Small-scale

0.710

High

462057

HS90A
Heat shock protein HSP 90-alpha

4

12

Small-scale

0.683

High

936972

CASP9
Caspase-9

1

20

Small-scale

0.665

High

1416601

CARD6
Caspase recruitment domain-containing protein 6

1

6

Small-scale

0.665

High

1446612

NLRC4
NLR family CARD domain-containing protein 4

1

15

Small-scale

0.665

High

1096521

PAK1
Serine/threonine-protein kinase PAK 1

1

2

High-throughput

0.665

High

1490476

SGT1
Protein SGT1 homolog

3

13

Small-scale

0.650

High

50005

IRGM
Immunity-related GTPase family M protein

2

2

Small-scale

0.624

High

712903

CASP1
Caspase-1

1

20

Small-scale

0.618

High

840128

CASP2
Caspase-2

1

20

Small-scale

0.618

High

885720

CASP4
Caspase-4

1

20

Small-scale

0.618

High

1438567

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

17

Small-scale

0.618

High

1227726

A16L1
Autophagy-related protein 16-1

2

7

Small-scale

0.611

High

564578

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

943746

SOX8
Transcription factor SOX-8

1

1

High-throughput

0.541

High

615147

GBRB1
Gamma-aminobutyric acid receptor subunit beta-1

1

0

High-throughput

0.518

High

1272598

CSN6
COP9 signalosome complex subunit 6

1

2

Small-scale

0.515

High

384585

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.515

High

386373

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

15

High-throughput

0.515

High

570635

GFAP
Glial fibrillary acidic protein

1

11

High-throughput

0.515

High

844106

HD
Huntingtin

1

2

High-throughput

0.515

High

1199406

GLE1
mRNA export factor GLE1

1

3

High-throughput

0.515

High

1094445

CSN1
COP9 signalosome complex subunit 1

1

0

Small-scale

0.506

High

1462387

CSN3
COP9 signalosome complex subunit 3

1

1

Small-scale

0.506

High

1279806

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1369719

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

75615

B3KTT5
cDNA FLJ38698 fis, clone KIDNE2002015, highly similar to HEAT SHOCK 70 kDa PROTEIN 1

1

11

High-throughput

0.479

High

193056

CFLAR
CASP8 and FADD-like apoptosis regulator

1

20

Small-scale

0.479

High

939666

BID
BH3-interacting domain death agonist

1

1

Small-scale

0.479

High

1014049

RL36A
Large ribosomal subunit protein eL42

1

1

High-throughput

0.479

High

1098172

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.479

High

1106134

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

9

High-throughput

0.479

High

1108296

SQSTM
Sequestosome-1

1

5

Small-scale

0.479

High

1132469

CASP8
Caspase-8

1

20

Small-scale

0.479

High

1151688

TRIP6
Thyroid receptor-interacting protein 6

1

2

Small-scale

0.479

High

1153619

MLF2
Myeloid leukemia factor 2

1

2

High-throughput

0.479

High

1158608

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.479

High

1198806

Q53FC7
Heat shock 70 kDa protein 6

1

10

High-throughput

0.479

High

1245586

Q6PK50
HSP90AB1 protein

1

14

High-throughput

0.479

High

1249458

OLFM4
Olfactomedin-4

1

3

Small-scale

0.479

High

1308614

NUDC3
NudC domain-containing protein 3

1

1

High-throughput

0.479

High

1370475

CSN5
COP9 signalosome complex subunit 5

1

5

Small-scale

0.479

High

1384551

Q96BE0
Heat shock cognate 71 kDa protein

1

13

High-throughput

0.479

High

1406140

CSN8
COP9 signalosome complex subunit 8

1

1

Small-scale

0.479

High

1414806

TRAF4
TNF receptor-associated factor 4

1

11

Small-scale

0.479

High

1437983

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.479

High

1458848

CSN7A
COP9 signalosome complex subunit 7a

1

1

Small-scale

0.479

High

1460461

FKBPL
FK506-binding protein-like

1

8

High-throughput

0.479

High

1460795

HSPB8
Heat shock protein beta-8

1

3

Small-scale

0.479

High

1490477

MAGD1
Melanoma-associated antigen D1

1

2

High-throughput

0.479

High

165436

PSA7
Proteasome subunit alpha type-7

1

0

Small-scale

0.458

High

294541

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

1144222

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.458

High

76591

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

10

High-throughput

0.437

High

1138218

ACAP1
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

1

1

Small-scale

0.437

High

1409578

Q9BPW0
Serine/threonine-protein phosphatase

1

7

High-throughput

0.437

High

1326155

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025