HitPredict

Interactor 1: IPO5 (O00410)
Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)
Gene: IPO5

Interactor 2: PWP1 (Q13610)
Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502)
Gene: PWP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005794 - Golgi apparatus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1097 Hs			1 501
+	Hs
		127239 IPO5_HUMAN (1-1097): 0: 784: 100.00		GBB1_HUMAN (247-492): 2.59e-37: 141: 15.75
+	Hs
		127234 IPO5_HUMAN (1-1097): 0: 784: 100.00		WDR5_HUMAN (7-223): 2.82e-12: 69.6: 10.08
+	Sc
		597844 IMB4_YEAST (6-1095): 1.28e-113: 381: 18.55		PWP1_YEAST (6-498): 2.16e-89: 286: 32.86
+	Hs
		1256964 IPO4_HUMAN (21-1097): 1.13e-110: 372: 19.33		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09
+	Hs
		921660 IPO4_HUMAN (21-1097): 1.13e-110: 372: 19.33		GBB2_HUMAN (247-492): 1.81e-36: 139: 15.75
+	Sc
		765945 IMB4_YEAST (6-1095): 1.28e-113: 381: 18.55		HAT2_YEAST (250-415): 8.71e-11: 65.9: 25.58
+	Hs
		903383 IPO4_HUMAN (21-1097): 1.13e-110: 372: 19.33		WDR5_HUMAN (7-223): 2.82e-12: 69.6: 10.08
+	Hs
		1060861 IMB1_HUMAN (537-1094): 1.75e-11: 70.8: 11.11		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09