Protein: CD68
Macrosialin (Gp110) (CD antigen CD68)

Gene: CD68
Organism: Homo sapiens
Interactions: 58
UniProt ID: P34810

Gene Ontology (top 5):
GO:0002437 - inflammatory response to antigenic stimulus
GO:0002605 - negative regulation of dendritic cell antigen processing and presentation
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

760760

CD276
CD276 antigen

1

1

High-throughput

0.691

High

480727

LEG1
Galectin-1

4

10

High-throughput

0.691

High

760756

KIF14
Kinesin-like protein KIF14

4

4

High-throughput

0.691

High

760748

SYRC
Arginine--tRNA ligase, cytoplasmic

3

1

High-throughput

0.667

High

760788

5MP1
eIF5-mimic protein 1

3

1

High-throughput

0.667

High

705253

GRN
Progranulin

4

0

High-throughput

0.661

High

164540

TNPO2
Transportin-2

4

2

High-throughput

0.623

High

760759

MTX3
Metaxin-3

3

2

High-throughput

0.609

High

590250

MUC1
Mucin-1

2

1

High-throughput

0.606

High

760762

KTN1
Kinectin

2

4

High-throughput

0.606

High

760765

MAL2
Protein MAL2

2

1

High-throughput

0.606

High

760768

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

1

High-throughput

0.606

High

760782

CLC2D
C-type lectin domain family 2 member D

2

5

High-throughput

0.606

High

760781

GCP4
Gamma-tubulin complex component 4

2

0

High-throughput

0.585

High

760761

T179B
Transmembrane protein 179B

2

0

High-throughput

0.580

High

760767

PKHB2
Pleckstrin homology domain-containing family B member 2

2

0

High-throughput

0.580

High

127290

LEG8
Galectin-8

2

10

Small-scale

0.571

High

760752

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

1

High-throughput

0.558

High

563304

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.541

High

760763

SPA12
Serpin A12

1

1

High-throughput

0.536

High

458296

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.529

High

760751

GNDS
Ral guanine nucleotide dissociation stimulator

1

0

High-throughput

0.518

High

609596

LEG3
Galectin-3

1

10

High-throughput

0.479

High

760757

IRF4
Interferon regulatory factor 4

1

2

Small-scale

0.479

High

609908

SPI1
Transcription factor PU.1

1

3

Small-scale

0.470

High

738955

ELF1
ETS-related transcription factor Elf-1

1

1

Small-scale

0.470

High

760750

FLI1
Friend leukemia integration 1 transcription factor

1

1

Small-scale

0.470

High

133957

IPO5
Importin-5

1

2

High-throughput

0.445

High

271674

HIP1R
Huntingtin-interacting protein 1-related protein

1

1

High-throughput

0.445

High

760753

MTX1
Metaxin-1

1

2

High-throughput

0.445

High

760771

COG8
Conserved oligomeric Golgi complex subunit 8

1

3

High-throughput

0.445

High

65339

TCAF2
TRPM8 channel-associated factor 2

1

0

High-throughput

0.426

High

760755

TPBG
Trophoblast glycoprotein

1

0

High-throughput

0.426

High

760764

EXOC8
Exocyst complex component 8

1

0

High-throughput

0.426

High

760770

ELMO2
Engulfment and cell motility protein 2

1

0

High-throughput

0.426

High

760773

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.426

High

760780

NCDN
Neurochondrin

1

0

High-throughput

0.426

High

760783

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.426

High

760784

COG5
Conserved oligomeric Golgi complex subunit 5

1

0

High-throughput

0.426

High

760785

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.426

High

760758

Q4LE60
TNPO2 variant protein

1

2

High-throughput

0.407

High

760772

SMG1
Serine/threonine-protein kinase SMG1

1

3

High-throughput

0.407

High

760774

UCK2
Uridine-cytidine kinase 2

1

1

High-throughput

0.407

High

760776

CSN7B
COP9 signalosome complex subunit 7b

1

1

High-throughput

0.407

High

208025

TTI1
TELO2-interacting protein 1 homolog

4

0

High-throughput

0.360

High

760769

SAAL1
Protein SAAL1

4

0

High-throughput

0.360

High

353035

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

760754

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

760766

TOM6
Mitochondrial import receptor subunit TOM6 homolog

2

0

High-throughput

0.316

High

760787

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.298

High

612895

EGR1
Early growth response protein 1

1

0

Small-scale

0.249

Low

137190

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.232

Low

760749

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.232

Low

760775

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.232

Low

760777

F1142
Protein FAM114A2

1

0

High-throughput

0.232

Low

760778

COMD8
COMM domain-containing protein 8

1

0

High-throughput

0.232

Low

760779

SACS
Sacsin

1

0

High-throughput

0.232

Low

760786

EXC6B
Exocyst complex component 6B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025