HitPredict

Interactor 1: RAB8B (Q92930)
Ras-related protein Rab-8B
Gene: RAB8B

Interactor 2: RAB1B (Q9H0U4)
Ras-related protein Rab-1B (EC 3.6.5.2)
Gene: RAB1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 201
+	Hs
		895549 RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20		RAB1B_HUMAN (1-201): 2.62e-93: 272: 100.00
+	Mm
		895587 RAB10_MOUSE (1-197): 7.97e-95: 276: 70.20		RAB1B_MOUSE (1-201): 5.33e-93: 271: 99.01
+	Hs
		918944 RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94		RAB1B_HUMAN (1-201): 2.62e-93: 272: 100.00
+	Mm
		919000 RAB1A_MOUSE (1-204): 9.22e-93: 271: 52.94		RAB1B_MOUSE (1-201): 5.33e-93: 271: 99.01
+	Zm
		73944 B4FAE1_MAIZE (1-205): 2.4e-94: 275: 53.66		B4FAE1_MAIZE (1-200): 5.73e-91: 266: 75.74
+	Hs
		895532 RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20		RAB1C_HUMAN (1-201): 8.93e-90: 263: 95.52
+	Hs
		918846 RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94		RAB1A_HUMAN (1-201): 5.62e-91: 266: 92.57
+	Mm
		877188 RAB10_MOUSE (1-197): 7.97e-95: 276: 70.20		RAB8A_MOUSE (1-199): 6.31e-85: 251: 51.50
+	Mm
		877189 RAB8B_MOUSE (1-207): 2.04e-93: 273: 98.55		RAB8A_MOUSE (1-199): 6.31e-85: 251: 51.50
+	Hs
		895472 RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20		RB11A_HUMAN (2-201): 1.09e-83: 248: 46.41
+	Mm
		895589 RAB10_MOUSE (1-197): 7.97e-95: 276: 70.20		RAB13_MOUSE (1-199): 1.84e-82: 245: 50.25
+	Hs
		894709 RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20		RAB8A_HUMAN (1-199): 1.31e-81: 243: 52.50
+	Hs
		913992 RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94		RB11A_HUMAN (2-201): 1.09e-83: 248: 46.41
+	Hs
		845875 RAB8B_HUMAN (1-207): 4.25e-93: 272: 100.00		RAB13_HUMAN (1-200): 4.82e-82: 243: 51.50
+	Hs
		894787 RAB8B_HUMAN (1-207): 4.25e-93: 272: 100.00		RAB8A_HUMAN (1-199): 1.31e-81: 243: 52.50
+	Hs
		918879 RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94		RB11B_HUMAN (2-201): 4.16e-82: 244: 45.97
+	Hs
		894715 RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94		RAB8A_HUMAN (1-199): 1.31e-81: 243: 52.50
+	Hs
		1079964 RAB1B_HUMAN (1-204): 3.94e-92: 269: 51.96		RB11B_HUMAN (2-201): 4.16e-82: 244: 45.97
+	Hs
		845881 RAB1B_HUMAN (1-204): 3.94e-92: 269: 51.96		RAB13_HUMAN (1-200): 4.82e-82: 243: 51.50