HitPredict

Interactor 1: MED12 (Q93074)
Mediator of RNA polymerase II transcription subunit 12 (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein)
Gene: MED12

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2177 Hs			1 669
+	Hs
		1310129 WDR33_HUMAN (1594-2167): 1.1e-24: 115: 8.81		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Mm
		1111938 ZMIZ1_MOUSE (1800-2176): 2.5e-15: 84.6: 10.85		SMCA4_MOUSE (18-526): 1.74e-30: 130: 12.69
+	Hs
		846837 CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45		SMCA2_HUMAN (18-531): 1.58e-34: 143: 13.60
+	Hs
		846820 ARI1B_HUMAN (1839-2172): 5.1e-10: 67.3: 14.20		SMCA2_HUMAN (18-531): 1.58e-34: 143: 13.60
+	Mm
		93512 ARI1B_MOUSE (1679-2177): 7.37e-10: 66.9: 7.51		SMCA2_MOUSE (18-531): 2.04e-34: 142: 14.48
+	Mm
		57185 CHD7_MOUSE (1920-2177): 3.13e-11: 71.5: 13.60		SMCA4_MOUSE (18-526): 1.74e-30: 130: 12.69
+	Hs
		847041 CBP_HUMAN (1582-2176): 2.69e-11: 71.5: 13.45		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Hs
		847103 CHD7_HUMAN (1825-2174): 2.18e-10: 68.8: 10.05		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Hs
		847021 ARI1B_HUMAN (1839-2172): 5.1e-10: 67.3: 14.20		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Mm
		93508 ARI1B_MOUSE (1679-2177): 7.37e-10: 66.9: 7.51		SMCA4_MOUSE (18-526): 1.74e-30: 130: 12.69
+	Hs
		1145923 WDR33_HUMAN (1594-2167): 1.1e-24: 115: 8.81		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		149481 PCLO_HUMAN (1550-2174): 1.26e-24: 115: 8.71		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		149232 DIDO1_HUMAN (1479-2099): 1.5e-18: 95.4: 10.74		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		1172598 CRACD_HUMAN (1744-2168): 6.51e-13: 76.8: 16.78		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		99714 F5H1N7_HUMAN (1744-2168): 7.44e-13: 76.4: 16.78		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		148737 BPTF_HUMAN (1686-2176): 1.04e-14: 83.1: 11.51		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		1145900 ATX2_HUMAN (1645-2176): 2.64e-11: 71.5: 9.32		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		148240 SC31A_HUMAN (1897-2176): 1.29e-11: 72.3: 11.54		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		149177 EP400_HUMAN (1812-2174): 7.89e-09: 63.4: 17.63		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36