HitPredict

Interactor 1: RGPD4 (Q7Z3J3)
RanBP2-like and GRIP domain-containing protein 4
Gene: RGPD4

Interactor 2: RGPD5 (Q99666)
RANBP2-like and GRIP domain-containing protein 5/6 (Ran-binding protein 2-like 1/2) (RanBP2-like 1/2) (RanBP2L1) (RanBP2L2) (Sperm membrane protein BS-63)
Gene: RGPD5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GRIP~GRIP, Rab_bind~Rab_bind, Ran_BP1~Ran_BP1
Common GO terms	GO:0005643 - nuclear pore GO:0005737 - cytoplasm GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1758 Hs			1 1765
+	Hs
		161626 RGPD4_HUMAN (1-1758): 0: 2408: 100.00		RGPD8_HUMAN (1-1765): 0: 2162: 99.49
+	Hs
		66724 RGPD3_HUMAN (1-1758): 0: 2400: 98.29		RGPD8_HUMAN (1-1765): 0: 2162: 99.49
+	Hs
		66765 RGPD3_HUMAN (1-1758): 0: 2400: 98.29		RGPD5_HUMAN (1-1765): 0: 2162: 100.00
+	Hs
		161639 RGPD8_HUMAN (1-1758): 0: 2363: 95.05		RGPD5_HUMAN (1-1765): 0: 2162: 100.00
+	Hs
		515826 RGPD4_HUMAN (1-1758): 0: 2408: 100.00		RGPD2_HUMAN (1-1760): 0: 2110: 93.41
+	Hs
		66756 RGPD4_HUMAN (1-1758): 0: 2408: 100.00		RGPD3_HUMAN (1-1757): 0: 2109: 95.56
+	Hs
		66734 RGPD3_HUMAN (1-1758): 0: 2400: 98.29		RGPD2_HUMAN (1-1760): 0: 2110: 93.41
+	Hs
		515796 RGPD4_HUMAN (1-1758): 0: 2408: 100.00		RGPD1_HUMAN (26-1760): 0: 2095: 93.83
+	Hs
		66733 RGPD3_HUMAN (1-1758): 0: 2400: 98.29		RGPD1_HUMAN (26-1760): 0: 2095: 93.83
+	Hs
		161588 RGPD8_HUMAN (1-1758): 0: 2363: 95.05		RGPD2_HUMAN (1-1760): 0: 2110: 93.41
+	Hs
		161587 RGPD8_HUMAN (1-1758): 0: 2363: 95.05		RGPD1_HUMAN (26-1760): 0: 2095: 93.83
+	Hs
		890521 RGPD4_HUMAN (1-1758): 0: 2408: 100.00		RBP2_HUMAN (686-1191): 1.36e-30: 134: 23.67
+	Hs
		66742 RGPD3_HUMAN (1-1758): 0: 2400: 98.29		RBP2_HUMAN (686-1191): 1.36e-30: 134: 23.67
+	Hs
		66740 RGPD3_HUMAN (1-1758): 0: 2400: 98.29		RANG_HUMAN (1014-1207): 2.49e-27: 113: 37.88
+	Hs
		161651 RGPD8_HUMAN (1-1758): 0: 2363: 95.05		NUP50_HUMAN (1124-1466): 1.63e-33: 138: 18.68
+	Hs
		161597 RGPD8_HUMAN (1-1758): 0: 2363: 95.05		RBP2_HUMAN (686-1191): 1.36e-30: 134: 23.67