HitPredict

Interactor 1: RGPD3 (A6NKT7)
RanBP2-like and GRIP domain-containing protein 3
Gene: RGPD3

Interactor 2: RGPD2 (P0DJD1)
RANBP2-like and GRIP domain-containing protein 2 (Ran-binding protein 2-like 2) (RanBP2-like 2) (RanBP2L2)
Gene: RGPD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GRIP~GRIP, Rab_bind~Rab_bind, Ran_BP1~Ran_BP1, TPR_2~TPR_8
Common GO terms	GO:0005643 - nuclear pore GO:0005737 - cytoplasm GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1758 Hs			1 1756
+	Hs
		515826 RGPD4_HUMAN (1-1758): 0: 2219: 98.29		RGPD2_HUMAN (1-1756): 0: 2444: 100.00
+	Hs
		66733 RGPD3_HUMAN (1-1758): 0: 2226: 100.00		RGPD1_HUMAN (23-1756): 0: 2419: 99.83
+	Hs
		515796 RGPD4_HUMAN (1-1758): 0: 2219: 98.29		RGPD1_HUMAN (23-1756): 0: 2419: 99.83
+	Hs
		161588 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		RGPD2_HUMAN (1-1756): 0: 2444: 100.00
+	Hs
		66765 RGPD3_HUMAN (1-1758): 0: 2226: 100.00		RGPD5_HUMAN (1-1751): 0: 2395: 93.41
+	Hs
		66724 RGPD3_HUMAN (1-1758): 0: 2226: 100.00		RGPD8_HUMAN (1-1750): 0: 2394: 93.46
+	Hs
		1277160 RGPD4_HUMAN (1-1758): 0: 2219: 98.29		RGPD5_HUMAN (1-1751): 0: 2395: 93.41
+	Hs
		161626 RGPD4_HUMAN (1-1758): 0: 2219: 98.29		RGPD8_HUMAN (1-1750): 0: 2394: 93.46
+	Hs
		161587 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		RGPD1_HUMAN (23-1756): 0: 2419: 99.83
+	Hs
		66756 RGPD3_HUMAN (1-1758): 0: 2226: 100.00		RGPD4_HUMAN (1-1748): 0: 2368: 95.34
+	Hs
		161639 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		RGPD5_HUMAN (1-1751): 0: 2395: 93.41
+	Hs
		66742 RGPD3_HUMAN (1-1758): 0: 2226: 100.00		RBP2_HUMAN (793-1184): 2.03e-39: 163: 32.23
+	Hs
		890521 RGPD4_HUMAN (1-1758): 0: 2219: 98.29		RBP2_HUMAN (793-1184): 2.03e-39: 163: 32.23
+	Hs
		66740 RGPD3_HUMAN (1-1758): 0: 2226: 100.00		RANG_HUMAN (1007-1200): 9.47e-40: 148: 37.88
+	Hs
		161597 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		RBP2_HUMAN (793-1184): 2.03e-39: 163: 32.23
+	Hs
		161651 RGPD8_HUMAN (1-1758): 0: 2192: 95.68		NUP50_HUMAN (740-1162): 2.44e-37: 149: 15.47