HitPredict

Interactor 1: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Interactor 2: SKP2A (Q9LPL4)
F-box protein SKP2A (FBL5-like protein) (AtFBL5) (SKP2-like protein 1) (AtSKP2;1)
Gene: SKP2A

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	18036202
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~F-box-like
Common GO terms	GO:0005634 - nucleus GO:0009734 - auxin-activated signaling pathway GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 738 At			1 360
+	At
		221522 CUL1_ARATH (1-738): 0: 837: 100.00		SKP2B_ARATH (1-360): 9.4e-80: 249: 83.06
+	At
		1277345 CUL1_ARATH (1-738): 0: 837: 100.00		EBF1_ARATH (59-356): 8.58e-29: 119: 19.03
+	Hs
		1042879 CUL3_HUMAN (1-738): 0: 796: 30.09		KDM2A_HUMAN (17-271): 4.14e-42: 158: 17.58
+	Hs
		1041833 CUL3_HUMAN (1-738): 0: 796: 30.09		FXL19_HUMAN (31-278): 6.4e-41: 154: 21.27
+	Hs
		1031192 CUL4A_HUMAN (13-738): 0: 788: 34.61		SKP2_HUMAN (16-315): 1.15e-44: 160: 23.53
+	At
		1277335 CUL1_ARATH (1-738): 0: 837: 100.00		AFB3_ARATH (3-354): 2.35e-22: 100: 16.50
+	At
		1173680 CUL1_ARATH (1-738): 0: 837: 100.00		EBF2_ARATH (177-345): 3.32e-21: 96.7: 23.12
+	At
		1277350 CUL1_ARATH (1-738): 0: 837: 100.00		GRH1_ARATH (6-285): 9.23e-20: 92.4: 17.82
+	Hs
		1042318 CUL3_HUMAN (1-738): 0: 796: 30.09		LRRC7_HUMAN (71-336): 1.18e-29: 122: 11.70
+	At
		1123013 CUL1_ARATH (1-738): 0: 837: 100.00		TIR1_ARATH (63-277): 8.74e-11: 65.2: 21.57
+	Hs
		1043217 CUL4A_HUMAN (13-738): 0: 788: 34.61		FXL15_HUMAN (135-348): 2.51e-28: 113: 23.28
+	Hs
		1031190 CUL1_HUMAN (4-738): 0: 729: 30.41		SKP2_HUMAN (16-315): 1.15e-44: 160: 23.53
+	Hs
		1042760 CUL3_HUMAN (1-738): 0: 796: 30.09		FXL17_HUMAN (63-251): 5.64e-19: 90.3: 22.22
+	Hs
		1041049 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL19_HUMAN (31-278): 6.4e-41: 154: 21.27
+	Hs
		1041197 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL15_HUMAN (135-348): 2.51e-28: 113: 23.28
+	Hs
		1041248 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL17_HUMAN (63-251): 5.64e-19: 90.3: 22.22
+	Hs
		1041100 CUL1_HUMAN (4-738): 0: 729: 30.41		KDM2B_HUMAN (146-357): 1.53e-17: 86: 15.42
+	Hs
		1041146 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL20_HUMAN (172-357): 1.1e-15: 79.9: 21.93
+	Hs
		1041088 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL14_HUMAN (3-229): 1.05e-13: 73.7: 24.67
+	Hs
		1041256 CUL1_HUMAN (4-738): 0: 729: 30.41		FBXL7_HUMAN (221-357): 1.25e-11: 67.6: 20.14