Protein: NECT2
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)

Gene: NECT2, NECTIN2
Organism: Homo sapiens
Interactions: 154
UniProt ID: Q92692

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0001675 - acrosome assembly
GO:0002860 - positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 - positive regulation of immunoglobulin mediated immune response
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1269111

NECT2
Nectin-2

7

17

Small-scale

0.968

High

1269129

NECT3
Nectin-3

6

19

Small-scale

0.952

High

1115376

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

3

3

Small-scale

0.879

High

350416

RASK
GTPase KRas

4

20

High-throughput

0.873

High

348836

RASN
GTPase NRas

3

20

High-throughput

0.827

High

349539

RASH
GTPase HRas

3

20

High-throughput

0.827

High

1218290

SPA12
Serpin A12

2

1

High-throughput

0.811

High

1198117

TM11B
Transmembrane protease serine 11B

2

15

High-throughput

0.789

High

423313

PDIA1
Protein disulfide-isomerase

2

5

High-throughput

0.783

High

1078223

CD226
CD226 antigen

2

18

Small-scale

0.768

High

914262

RB11A
Ras-related protein Rab-11A

2

7

High-throughput

0.754

High

915877

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

1189382

NT2NA
Notch homolog 2 N-terminal-like protein A

2

20

High-throughput

0.731

High

1269115

NECT4
Nectin-4

1

16

Small-scale

0.724

High

876459

AFAD
Afadin

5

17

Small-scale

0.710

High

1269130

PICK1
PRKCA-binding protein

4

5

Small-scale

0.702

High

344317

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.691

High

409542

HEPS
Serine protease hepsin

1

15

High-throughput

0.691

High

545146

PVR
Poliovirus receptor

1

18

High-throughput

0.691

High

702389

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

2

High-throughput

0.691

High

1269114

HVCN1
Voltage-gated hydrogen channel 1

1

2

High-throughput

0.691

High

1269118

TMPSD
Transmembrane protease serine 13

1

15

High-throughput

0.691

High

1269142

ST14
Suppressor of tumorigenicity 14 protein

1

15

High-throughput

0.691

High

1259935

TB22A
TBC1 domain family member 22A

3

1

High-throughput

0.667

High

427776

GP1BA
Platelet glycoprotein Ib alpha chain

1

20

High-throughput

0.665

High

1269117

MDFI
MyoD family inhibitor

4

1

High-throughput

0.644

High

1269123

DNJC5
DnaJ homolog subfamily C member 5

2

7

High-throughput

0.634

High

396387

APOD
Apolipoprotein D

2

1

High-throughput

0.628

High

1109753

CC50B
Cell cycle control protein 50B

2

1

High-throughput

0.628

High

120569

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

318197

DIRA3
GTP-binding protein Di-Ras3

1

8

High-throughput

0.618

High

436439

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

522105

CADH1
Cadherin-1

1

5

High-throughput

0.618

High

545540

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564634

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

591963

RAB4A
Ras-related protein Rab-4A

1

10

High-throughput

0.618

High

592415

RAB5A
Ras-related protein Rab-5A

1

10

High-throughput

0.618

High

648843

DPP4
Dipeptidyl peptidase 4

1

3

High-throughput

0.618

High

793412

MUC18
Cell surface glycoprotein MUC18

1

20

High-throughput

0.618

High

844662

RAB5C
Ras-related protein Rab-5C

1

10

High-throughput

0.618

High

845131

RAB7A
Ras-related protein Rab-7a

1

11

High-throughput

0.618

High

845647

RAB9A
Ras-related protein Rab-9A

1

12

High-throughput

0.618

High

852576

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

884556

RAB25
Ras-related protein Rab-25

1

7

High-throughput

0.618

High

892523

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

894277

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

895215

RAB2A
Ras-related protein Rab-2A

1

10

High-throughput

0.618

High

900759

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901212

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

925492

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

940514

CXAR
Coxsackievirus and adenovirus receptor

1

18

High-throughput

0.618

High

951203

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1070332

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

1076690

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1183488

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1269124

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1269126

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

67263

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.606

High

283229

RGS20
Regulator of G-protein signaling 20

2

2

High-throughput

0.606

High

1267465

NR4A3
Nuclear receptor subfamily 4 group A member 3

2

8

High-throughput

0.606

High

867742

SYRC
Arginine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

484677

NT2NC
Notch homolog 2 N-terminal-like protein C

1

20

High-throughput

0.594

High

1085456

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.587

High

507163

LAMP1
Lysosome-associated membrane glycoprotein 1

2

4

High-throughput

0.584

High

913029

ARF6
ADP-ribosylation factor 6

2

6

High-throughput

0.584

High

611302

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

0

High-throughput

0.580

High

1269121

BTBD1
BTB/POZ domain-containing protein 1

2

4

High-throughput

0.574

High

551225

ITF2
Transcription factor 4

2

1

High-throughput

0.553

High

829958

HXA1
Homeobox protein Hox-A1

2

4

High-throughput

0.553

High

887405

KR122
Keratin-associated protein 12-2

2

20

High-throughput

0.553

High

889610

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.553

High

991636

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

1134497

LCE1C
Late cornified envelope protein 1C

2

1

High-throughput

0.553

High

1135705

LCE2C
Late cornified envelope protein 2C

2

1

High-throughput

0.553

High

1216364

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

1071666

KS6A2
Ribosomal protein S6 kinase alpha-2

1

3

High-throughput

0.553

High

1108799

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

1

18

High-throughput

0.553

High

1146686

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.553

High

1171061

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

1173991

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

1

High-throughput

0.541

High

621328

PRPH2
Peripherin-2

1

4

High-throughput

0.536

High

654625

CALX
Calnexin

1

7

High-throughput

0.536

High

713858

RYK
Tyrosine-protein kinase RYK

1

20

High-throughput

0.536

High

1162837

BRID5
BRICHOS domain-containing protein 5

1

4

High-throughput

0.536

High

1187451

PLPR4
Phospholipid phosphatase-related protein type 4

1

1

High-throughput

0.536

High

1269113

T106A
Transmembrane protein 106A

1

4

High-throughput

0.536

High

1269138

CLC4A
C-type lectin domain family 4 member A

1

18

High-throughput

0.536

High

1269139

SIAT9
Lactosylceramide alpha-2,3-sialyltransferase

1

1

High-throughput

0.536

High

642126

KRA59
Keratin-associated protein 5-9

1

20

High-throughput

0.523

High

889352

KR107
Keratin-associated protein 10-7

1

20

High-throughput

0.523

High

1216677

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

High-throughput

0.523

High

1269128

LYRM4
LYR motif-containing protein 4

1

0

High-throughput

0.518

High

1264528

SSH1
Protein phosphatase Slingshot homolog 1

1

10

High-throughput

0.515

High

1165470

SBSN
Suprabasin

1

0

High-throughput

0.513

High

1269120

PANK2
Pantothenate kinase 2, mitochondrial

1

0

High-throughput

0.513

High

270963

SPAG6
Sperm-associated antigen 6

1

2

High-throughput

0.489

High

1269122

CST11
Cystatin-11

1

1

High-throughput

0.489

High

1269137

RSP14
Radial spoke head 14 homolog

1

4

High-throughput

0.489

High

171234

CTDSL
CTD small phosphatase-like protein

1

4

High-throughput

0.479

High

178707

STX7
Syntaxin-7

1

7

High-throughput

0.479

High

205779

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.479

High

279659

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

305573

ZFPL1
Zinc finger protein-like 1

1

3

High-throughput

0.479

High

433928

LYN
Tyrosine-protein kinase Lyn

1

13

High-throughput

0.479

High

567203

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.479

High

647161

1433T
14-3-3 protein theta

1

12

High-throughput

0.479

High

670140

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.479

High

683594

1433B
14-3-3 protein beta/alpha

1

12

High-throughput

0.479

High

881545

ARL4C
ADP-ribosylation factor-like protein 4C

1

20

High-throughput

0.479

High

904941

1433G
14-3-3 protein gamma

1

12

High-throughput

0.479

High

927368

1433Z
14-3-3 protein zeta/delta

1

12

High-throughput

0.479

High

973781

AKA12
A-kinase anchor protein 12

1

3

High-throughput

0.479

High

974955

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

982354

1433F
14-3-3 protein eta

1

12

High-throughput

0.479

High

1017740

STX4
Syntaxin-4

1

7

High-throughput

0.479

High

1084124

OCLN
Occludin

1

3

High-throughput

0.479

High

1152013

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1165811

LMBRL
Protein LMBR1L

1

5

High-throughput

0.479

High

1230310

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.479

High

1233601

ARL14
ADP-ribosylation factor-like protein 14

1

11

High-throughput

0.479

High

1256853

PARD3
Partitioning defective 3 homolog

1

15

High-throughput

0.479

High

1269112

CK052
Uncharacterized protein C11orf52

1

3

High-throughput

0.479

High

1269116

FMNL2
Formin-like protein 2

1

2

High-throughput

0.479

High

1269125

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1269132

ARL15
ADP-ribosylation factor-like protein 15

1

10

High-throughput

0.479

High

1269133

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1269135

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1269136

ZO2
Tight junction protein ZO-2

1

5

High-throughput

0.479

High

1269140

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.479

High

889103

KR105
Keratin-associated protein 10-5

1

20

High-throughput

0.470

High

1151157

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

1269134

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1269141

FUT9
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9

1

0

High-throughput

0.458

High

887918

CD81
CD81 antigen

1

10

High-throughput

0.445

High

592

NBPFJ
Neuroblastoma breakpoint family member 19

1

4

High-throughput

0.439

High

838175

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

888753

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.439

High

888950

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

1134582

LCE1E
Late cornified envelope protein 1E

1

1

High-throughput

0.439

High

132553

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

2

High-throughput

0.437

High

776163

ARL1
ADP-ribosylation factor-like protein 1

1

7

High-throughput

0.437

High

1110044

AR13B
ADP-ribosylation factor-like protein 13B

1

11

High-throughput

0.437

High

1200298

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

1

High-throughput

0.437

High

1203799

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1269127

E41LA
Band 4.1-like protein 4A

1

6

High-throughput

0.437

High

1085018

DREB
Drebrin

1

1

Small-scale

0.407

High

1139342

SYPL2
Synaptophysin-like protein 2

2

0

High-throughput

0.328

High

1269119

LOXE3
Hydroperoxide isomerase ALOXE3

2

0

High-throughput

0.328

High

150456

LCE2B
Late cornified envelope protein 2B

2

0

High-throughput

0.316

High

1136405

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.316

High

879701

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.282

High

1269131

DUS2L
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

1

0

High-throughput

0.282

High

1134627

LCE1F
Late cornified envelope protein 1F

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024