HitPredict

Interactor 1: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Interactor 2: SKI19 (Q9M0U9)
F-box protein SKIP19 (F-box/LRR-repeat protein 20) (SKP1-interacting partner 19)
Gene: SKIP19

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	12795696
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Cullin~F-box-like
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 738 At			1 302
+	At
		1277349 CUL1_ARATH (1-738): 0: 837: 100.00		FBW2_ARATH (15-248): 4.71e-51: 172: 30.29
+	At
		1352757 CUL2_ARATH (1-738): 0: 776: 69.14		FBW2_ARATH (15-248): 4.71e-51: 172: 30.29
+	At
		1277334 CUL1_ARATH (1-738): 0: 837: 100.00		SKP2A_ARATH (116-296): 1.74e-23: 100: 19.36
+	At
		221522 CUL1_ARATH (1-738): 0: 837: 100.00		SKP2B_ARATH (116-296): 5.64e-21: 93.2: 16.76
+	Hs
		1042879 CUL3_HUMAN (1-738): 0: 796: 30.09		KDM2A_HUMAN (9-247): 2.71e-33: 131: 16.13
+	Hs
		1031192 CUL4A_HUMAN (13-738): 0: 788: 34.61		SKP2_HUMAN (6-294): 5.44e-35: 132: 18.45
+	At
		1277345 CUL1_ARATH (1-738): 0: 837: 100.00		EBF1_ARATH (32-238): 8.16e-14: 73.6: 19.72
+	At
		1123013 CUL1_ARATH (1-738): 0: 837: 100.00		TIR1_ARATH (46-246): 2.33e-09: 60.1: 12.70
+	Hs
		1042760 CUL3_HUMAN (1-738): 0: 796: 30.09		FXL17_HUMAN (82-207): 1.43e-12: 69.7: 22.05
+	Hs
		1043217 CUL4A_HUMAN (13-738): 0: 788: 34.61		FXL15_HUMAN (2-230): 1.65e-14: 74.4: 18.63
+	Hs
		1031190 CUL1_HUMAN (4-738): 0: 729: 30.41		SKP2_HUMAN (6-294): 5.44e-35: 132: 18.45
+	Hs
		1041833 CUL3_HUMAN (1-738): 0: 796: 30.09		FXL19_HUMAN (119-295): 2.76e-09: 59.7: 12.68
+	Hs
		1041088 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL14_HUMAN (21-289): 4.28e-27: 111: 17.63
+	Hs
		1041146 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL20_HUMAN (88-246): 7.3e-20: 90.9: 22.75
+	Hs
		1041100 CUL1_HUMAN (4-738): 0: 729: 30.41		KDM2B_HUMAN (71-296): 5.84e-17: 83.2: 14.40
+	Hs
		1041229 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL12_HUMAN (21-249): 8.54e-16: 78.2: 22.79
+	Hs
		1041091 CUL1_HUMAN (4-738): 0: 729: 30.41		FBXL6_HUMAN (15-251): 1.21e-14: 75.9: 21.03
+	Hs
		1041197 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL15_HUMAN (2-230): 1.65e-14: 74.4: 18.63
+	Hs
		1041248 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL17_HUMAN (82-207): 1.43e-12: 69.7: 22.05
+	Hs
		1041049 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL19_HUMAN (119-295): 2.76e-09: 59.7: 12.68