HitPredict

Interactor 1: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Interactor 2: RUB1 (Q9SHE7)
Ubiquitin-NEDD8-like protein RUB1 [Cleaved into: Ubiquitin; NEDD8-like protein RUB1 (Ubiquitin-related protein 1) (AtRUB1)]
Gene: RUB1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	15319484, 22893627
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~ubiquitin, Cullin_Nedd8~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0009733 - response to auxin GO:0016567 - protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 738 At			1 156
+	At
		1091919 CUL1_ARATH (1-738): 0: 837: 100.00		UBQ3_ARATH (1-152): 2.92e-60: 190: 80.92
+	Hs
		475728 CUL3_HUMAN (1-738): 0: 796: 30.09		UBC_HUMAN (1-152): 5.68e-58: 193: 78.95
+	At
		1352191 CUL3A_ARATH (5-738): 0: 795: 33.92		RUB1_ARATH (1-156): 1.66e-61: 188: 100.00
+	Hs
		475729 CUL4A_HUMAN (13-738): 0: 788: 34.61		UBC_HUMAN (1-152): 5.68e-58: 193: 78.95
+	At
		1321116 CUL3B_ARATH (2-738): 0: 783: 31.74		RUB1_ARATH (1-156): 1.66e-61: 188: 100.00
+	Hs
		475730 CUL4B_HUMAN (12-738): 0: 774: 32.93		UBC_HUMAN (1-152): 5.68e-58: 193: 78.95
+	At
		1247030 CUL1_ARATH (1-738): 0: 837: 100.00		RUB2_ARATH (77-155): 9.76e-25: 94.6: 59.49
+	Hs
		475726 CUL1_HUMAN (4-738): 0: 729: 30.41		UBC_HUMAN (1-152): 5.68e-58: 193: 78.95
+	Rn
		78188 CUL3_RAT (1-738): 0: 795: 30.09		UBC_RAT (1-105): 3.61e-31: 119: 80.95
+	Mm
		477034 CUL3_MOUSE (1-738): 0: 794: 30.09		UBC_MOUSE (1-105): 2.61e-31: 119: 82.86
+	Rn
		71349 B2RYJ3_RAT (13-738): 0: 783: 33.52		UBC_RAT (1-105): 3.61e-31: 119: 80.95
+	Hs
		923983 CUL3_HUMAN (1-738): 0: 796: 30.09		RS27A_HUMAN (77-152): 8.46e-29: 105: 61.84
+	Hs
		923984 CUL4A_HUMAN (13-738): 0: 788: 34.61		RS27A_HUMAN (77-152): 8.46e-29: 105: 61.84
+	Hs
		475727 CUL2_HUMAN (1-738): 0: 688: 27.05		UBC_HUMAN (1-152): 5.68e-58: 193: 78.95
+	Hs
		923985 CUL4B_HUMAN (12-738): 0: 774: 32.93		RS27A_HUMAN (77-152): 8.46e-29: 105: 61.84
+	Hs
		475024 CUL4B_HUMAN (12-738): 0: 774: 32.93		UBB_HUMAN (1-77): 6.67e-28: 104: 94.81
+	Sp
		142914 CUL1_SCHPO (3-738): 0: 680: 27.94		UBI4P_SCHPO (1-152): 2.59e-58: 187: 79.61
+	Rn
		70071 B1WBY1_RAT (4-738): 0: 729: 30.41		UBC_RAT (1-105): 3.61e-31: 119: 80.95
+	Mm
		477001 CUL2_MOUSE (1-738): 0: 694: 26.53		UBC_MOUSE (1-105): 2.61e-31: 119: 82.86
+	Hs
		476148 CUL5_HUMAN (3-738): 0: 615: 24.14		UBC_HUMAN (1-152): 5.68e-58: 193: 78.95