Protein: SC5A5
Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Natrium iodide transporter) (Sodium-iodide symporter) (Na(+)/I(-) symporter) (Solute carrier family 5 member 5)

Gene: SC5A5, SLC5A5
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q92911

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006590 - thyroid hormone generation
GO:0006811 - monoatomic ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1370515

SC5A5
Sodium/iodide cotransporter

2

6

Small-scale

0.768

High

516707

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

0

High-throughput

0.676

High

1231450

ATLA3
Atlastin-3

2

1

High-throughput

0.628

High

256105

S19A2
Thiamine transporter 1

2

0

High-throughput

0.602

High

70401

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

1198936

ORML2
ORM1-like protein 2

2

3

High-throughput

0.574

High

1350626

SFXN5
Sideroflexin-5

2

1

High-throughput

0.574

High

609769

LEG3
Galectin-3

1

3

High-throughput

0.536

High

1370516

ARL5B
ADP-ribosylation factor-like protein 5B

1

1

High-throughput

0.536

High

1370519

YIPF3
Protein YIPF3

1

2

High-throughput

0.536

High

1370517

ERBIN
Erbin

1

1

Small-scale

0.527

High

1108648

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.513

High

1277343

NT2NA
Notch homolog 2 N-terminal-like protein A

1

2

High-throughput

0.481

High

517078

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.470

High

596

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.460

High

358766

LDHA
L-lactate dehydrogenase A chain

1

0

Small-scale

0.458

High

402980

ANXA1
Annexin A1

1

0

Small-scale

0.458

High

612276

ARF4
ADP-ribosylation factor 4

1

0

Small-scale

0.458

High

639394

5NTD
5'-nucleotidase

1

0

Small-scale

0.458

High

656213

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

Small-scale

0.458

High

921738

COPB
Coatomer subunit beta

1

0

Small-scale

0.458

High

934949

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

992899

RACK1
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

1147496

RHEB
GTP-binding protein Rheb

1

0

Small-scale

0.458

High

1163659

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

Small-scale

0.458

High

1356969

PDC6I
Programmed cell death 6-interacting protein

1

0

Small-scale

0.458

High

1370520

EHD1
EH domain-containing protein 1

1

0

Small-scale

0.458

High

1307430

KRA13
Keratin-associated protein 1-3

1

1

High-throughput

0.439

High

1370521

SAR1A
Small COPII coat GTPase SAR1A

1

1

Small-scale

0.437

High

1180683

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.279

Low

1225957

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

1370518

KRA31
Keratin-associated protein 3-1

1

0

High-throughput

0.251

Low

347220

BAG2
BAG family molecular chaperone regulator 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025