HitPredict

Interactor 1: PSA7 (Q95005)
Proteasome subunit alpha type-7 (Proteasome subunit alpha 4)
Gene: pas-4

Interactor 2: PSA4 (Q9N599)
Proteasome subunit alpha type-4 (Proteasome subunit alpha 3)
Gene: pas-3

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26952210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 253 Ce			1 250
+	Zm
		85792 C0PFK3_MAIZE (4-238): 5.91e-104: 303: 33.48		C0PFK3_MAIZE (1-241): 3.93e-103: 300: 34.54
+	Ss
		94582 F1SBA5_PIG (2-234): 2.16e-99: 291: 59.66		F2Z5L7_PIG (4-249): 1.4e-102: 300: 29.37
+	Hs
		156223 PSA7_HUMAN (1-234): 5.28e-99: 290: 63.25		PSA1_HUMAN (4-249): 1.4e-102: 300: 29.37
+	Hs
		637494 PSMA8_HUMAN (2-234): 2.32e-95: 281: 57.74		PSA1_HUMAN (4-249): 1.4e-102: 300: 29.37
+	Hs
		637325 PSA5_HUMAN (2-236): 1.12e-93: 277: 34.17		PSA1_HUMAN (4-249): 1.4e-102: 300: 29.37
+	Hs
		156226 PSA7_HUMAN (1-234): 5.28e-99: 290: 63.25		PSA4_HUMAN (1-234): 2.88e-95: 281: 67.51
+	Ce
		1278559 PSA7_CAEEL (1-253): 5.13e-102: 298: 100.00		PSA7_CAEEL (4-235): 2.15e-88: 263: 31.92
+	Hs
		156266 PSA7_HUMAN (1-234): 5.28e-99: 290: 63.25		PSA6_HUMAN (2-241): 1.34e-91: 271: 33.61
+	Hs
		156328 PSA7_HUMAN (1-234): 5.28e-99: 290: 63.25		PSMA8_HUMAN (1-235): 6.78e-91: 270: 35.25
+	Hs
		638067 PSA5_HUMAN (2-236): 1.12e-93: 277: 34.17		PSA4_HUMAN (1-234): 2.88e-95: 281: 67.51
+	Hs
		156169 PSA7_HUMAN (1-234): 5.28e-99: 290: 63.25		PSA7_HUMAN (5-235): 8.4e-90: 267: 36.33
+	Hs
		156230 PSA7_HUMAN (1-234): 5.28e-99: 290: 63.25		PSA5_HUMAN (3-237): 5.48e-89: 265: 33.61
+	Dm
		574027 PSA5_DROME (2-237): 5.33e-95: 280: 32.92		PSA4_DROME (1-239): 1.73e-91: 271: 64.90
+	Hs
		656276 PSMA8_HUMAN (2-234): 2.32e-95: 281: 57.74		PSA5_HUMAN (3-237): 5.48e-89: 265: 33.61
+	Hs
		108927 PSA5_HUMAN (2-236): 1.12e-93: 277: 34.17		H0YKT8_HUMAN (25-201): 4.33e-83: 247: 65.36
+	Ce
		1099869 PSA7_CAEEL (1-253): 5.13e-102: 298: 100.00		PSA2_CAEEL (1-230): 7.42e-45: 152: 38.79
+	Dm
		771303 PSA5_DROME (2-237): 5.33e-95: 280: 32.92		PSA2_DROME (4-212): 6.05e-43: 147: 39.05
+	Dm
		1278657 PSA5_DROME (2-237): 5.33e-95: 280: 32.92		PSA6_DROME (5-238): 1.37e-41: 144: 36.13