HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 579 Hs			1 464
+	Hs
		379960 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		127974 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		348086 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		379428 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379692 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379429 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		380081 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379728 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379365 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		346846 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		379683 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		378957 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		347530 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		346847 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		348394 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		347594 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		346697 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		347503 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		345797 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		346354 PCBP3_HUMAN (134-272): 5.55e-10: 63.3: 20.86		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16