HitPredict

Interactor 1: UBE2F (Q969M7)
NEDD8-conjugating enzyme UBE2F (EC 2.3.2.32) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F)
Gene: UBE2F

Interactor 2: RBX2 (Q9UBF6)
RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)
Gene: RNF7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 19250909, 25912140, 27591266, 29958295, 34518685, 35982156, 33184273, 36253371, 23300442
Identification Methods pull down, affinity chromatography technology, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-rbx1
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019788 - NEDD8 transferase activity
GO:0043687 - post-translational protein modification
GO:0045116 - protein neddylation
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 185
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024