Protein: TNPO3
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)

Gene: TNPO3
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q9Y5L0

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0005642 - annulate lamellae
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1120012

CIRBP
Cold-inducible RNA-binding protein

2

9

High-throughput

0.811

High

1127290

RBM39
RNA-binding protein 39

2

9

High-throughput

0.789

High

889846

CLK3
Dual specificity protein kinase CLK3

5

11

High-throughput

0.725

High

1491705

TNPO3
Transportin-3

1

11

Small-scale

0.716

High

1453564

PD1L1
Programmed cell death 1 ligand 1

4

20

High-throughput

0.694

High

326393

SCAF4
SR-related and CTD-associated factor 4

1

7

High-throughput

0.691

High

375042

RASH
GTPase HRas

1

5

High-throughput

0.691

High

988242

TRA2B
Transformer-2 protein homolog beta

1

14

High-throughput

0.691

High

1099054

SRSF9
Serine/arginine-rich splicing factor 9

1

18

High-throughput

0.691

High

1134096

ZN638
Zinc finger protein 638

1

1

High-throughput

0.691

High

1160358

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

13

High-throughput

0.691

High

1399805

RBM14
RNA-binding protein 14

1

8

High-throughput

0.691

High

1454731

RBM27
RNA-binding protein 27

1

6

High-throughput

0.691

High

291716

XRP2
Protein XRP2

3

5

High-throughput

0.667

High

845497

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

12

High-throughput

0.667

High

1177256

MICA
MHC class I polypeptide-related sequence A

3

4

High-throughput

0.667

High

1461795

FZD10
Frizzled-10

3

6

High-throughput

0.662

High

1446696

LUC7L
Putative RNA-binding protein Luc7-like 1

4

1

High-throughput

0.638

High

1097927

STX5
Syntaxin-5

3

0

High-throughput

0.638

High

262346

SCN2B
Sodium channel regulatory subunit beta-2

4

19

High-throughput

0.630

High

1231163

SCAR3
Scavenger receptor class A member 3

4

1

High-throughput

0.630

High

889688

CLK2
Dual specificity protein kinase CLK2

2

11

High-throughput

0.628

High

173614

XPO1
Exportin-1

1

13

Small-scale

0.618

High

775626

NU214
Nuclear pore complex protein Nup214

1

20

Small-scale

0.618

High

1061230

SRSF1
Serine/arginine-rich splicing factor 1

1

17

Small-scale

0.618

High

1418661

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

8

High-throughput

0.618

High

564616

CFTR
Cystic fibrosis transmembrane conductance regulator

2

10

High-throughput

0.611

High

332725

LYPD3
Ly6/PLAUR domain-containing protein 3

3

2

High-throughput

0.609

High

1291721

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

9

High-throughput

0.609

High

1394330

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

12

High-throughput

0.609

High

1405354

P2RX4
P2X purinoceptor 4

3

2

High-throughput

0.609

High

1431473

P2Y12
P2Y purinoceptor 12

3

20

High-throughput

0.609

High

284634

ECI2
Enoyl-CoA delta isomerase 2

2

2

High-throughput

0.606

High

341882

K2C75
Keratin, type II cytoskeletal 75

2

6

High-throughput

0.606

High

584824

NDKA
Nucleoside diphosphate kinase A

2

2

High-throughput

0.606

High

721750

GCH1
GTP cyclohydrolase 1

2

1

High-throughput

0.606

High

950737

KR108
Keratin-associated protein 10-8

2

2

High-throughput

0.606

High

1110327

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

5

High-throughput

0.606

High

1110430

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

5

High-throughput

0.606

High

1110599

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

5

High-throughput

0.606

High

1118271

BLMH
Bleomycin hydrolase

2

1

High-throughput

0.606

High

835425

VIPR2
Vasoactive intestinal polypeptide receptor 2

3

7

High-throughput

0.604

High

1293942

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

14

High-throughput

0.604

High

1330763

SIGL1
SIGLEC family-like protein 1

3

7

High-throughput

0.604

High

1032683

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.602

High

638562

FPR1
fMet-Leu-Phe receptor

2

20

High-throughput

0.601

High

1162724

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

1

High-throughput

0.590

High

364093

EGFR
Epidermal growth factor receptor

2

17

High-throughput

0.584

High

1095073

DUS4
Dual specificity protein phosphatase 4

2

9

High-throughput

0.584

High

1358068

PPR1C
Protein phosphatase 1 regulatory subunit 1C

2

0

High-throughput

0.580

High

587367

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

2

1

High-throughput

0.574

High

622721

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

20

High-throughput

0.574

High

702873

5HT2C
5-hydroxytryptamine receptor 2C

2

9

High-throughput

0.574

High

749306

CD70
CD70 antigen

2

3

High-throughput

0.574

High

898397

BCAM
Basal cell adhesion molecule

2

4

High-throughput

0.574

High

939554

FCGRN
IgG receptor FcRn large subunit p51

2

4

High-throughput

0.574

High

1232156

VASN
Vasorin

2

4

High-throughput

0.574

High

1372447

P2RX5
P2X purinoceptor 5

2

2

High-throughput

0.574

High

1436023

PACC1
Proton-activated chloride channel

2

5

High-throughput

0.574

High

50740

HACL2
2-hydroxyacyl-CoA lyase 2

2

5

High-throughput

0.549

High

683379

TNR5
Tumor necrosis factor receptor superfamily member 5

2

20

High-throughput

0.549

High

754129

CD80
T-lymphocyte activation antigen CD80

2

20

High-throughput

0.549

High

1101716

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

20

High-throughput

0.549

High

1451769

OCAD1
OCIA domain-containing protein 1

2

2

High-throughput

0.549

High

210433

MTLR
Motilin receptor

1

19

High-throughput

0.536

High

321884

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

2

High-throughput

0.536

High

323015

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

5

High-throughput

0.536

High

351995

S1PR4
Sphingosine 1-phosphate receptor 4

1

20

High-throughput

0.536

High

388343

GLPA
Glycophorin-A

1

5

High-throughput

0.536

High

486646

TACD2
Tumor-associated calcium signal transducer 2

1

3

High-throughput

0.536

High

638266

S1PR1
Sphingosine 1-phosphate receptor 1

1

17

High-throughput

0.536

High

690437

STOM
Stomatin

1

10

High-throughput

0.536

High

833704

NAA10
N-alpha-acetyltransferase 10

1

4

High-throughput

0.536

High

872944

SOX2
Transcription factor SOX-2

1

11

High-throughput

0.536

High

905521

HCFC1
Host cell factor 1

1

5

High-throughput

0.536

High

911965

JAK3
Tyrosine-protein kinase JAK3

1

20

High-throughput

0.536

High

920918

ACLY
ATP-citrate synthase

1

1

High-throughput

0.536

High

935660

MFAP1
Microfibrillar-associated protein 1

1

2

High-throughput

0.536

High

967081

1433G
14-3-3 protein gamma

1

10

High-throughput

0.536

High

1022996

EFNB1
Ephrin-B1

1

10

High-throughput

0.536

High

1124584

MAP7
Ensconsin

1

16

High-throughput

0.536

High

1128166

DHX8
ATP-dependent RNA helicase DHX8

1

4

High-throughput

0.536

High

1405514

SCAFB
Protein SCAF11

1

3

High-throughput

0.536

High

1412925

NAA11
N-alpha-acetyltransferase 11

1

4

High-throughput

0.536

High

1413335

DIDO1
Death-inducer obliterator 1

1

5

High-throughput

0.536

High

1438846

NCOA5
Nuclear receptor coactivator 5

1

1

High-throughput

0.536

High

1449267

RAD18
E3 ubiquitin-protein ligase RAD18

1

3

High-throughput

0.536

High

831721

CCNF
Cyclin-F

1

15

High-throughput

0.515

High

1437829

BRF2
Transcription factor IIIB 50 kDa subunit

1

4

High-throughput

0.515

High

1491693

PHLA3
Pleckstrin homology-like domain family A member 3

1

1

High-throughput

0.515

High

228402

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.513

High

1214390

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

1216426

FAXC
Failed axon connections homolog

1

0

High-throughput

0.513

High

1310561

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1357104

CATIN
Splicing factor Cactin

1

0

High-throughput

0.513

High

1358232

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

1397793

KAD7
Adenylate kinase 7

1

0

High-throughput

0.513

High

1434741

STEEP
STING ER exit protein

1

0

High-throughput

0.513

High

1437713

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

16

High-throughput

0.508

High

1491235

CHMP3
Charged multivesicular body protein 3

1

13

High-throughput

0.508

High

1371810

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.501

High

71264

HIDE1
Protein HIDE1

1

2

High-throughput

0.489

High

133324

P2Y10
Putative P2Y purinoceptor 10

1

20

High-throughput

0.489

High

141794

MFNG
Beta-1,3-N-acetylglucosaminyltransferase manic fringe

1

7

High-throughput

0.489

High

166077

FFAR1
Free fatty acid receptor 1

1

20

High-throughput

0.489

High

182855

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.489

High

209149

CYB5B
Cytochrome b5 type B

1

2

High-throughput

0.489

High

253917

TPST2
Protein-tyrosine sulfotransferase 2

1

2

High-throughput

0.489

High

322173

GLCE
D-glucuronyl C5-epimerase

1

1

High-throughput

0.489

High

376653

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

2

High-throughput

0.489

High

630387

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

20

High-throughput

0.489

High

640485

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

14

High-throughput

0.489

High

733100

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

7

High-throughput

0.489

High

770936

OPRM
Mu-type opioid receptor

1

14

High-throughput

0.489

High

774733

BASI
Basigin

1

14

High-throughput

0.489

High

833891

P2RY2
P2Y purinoceptor 2

1

20

High-throughput

0.489

High

845875

MUC18
Cell surface glycoprotein MUC18

1

4

High-throughput

0.489

High

868030

GLR
Glucagon receptor

1

14

High-throughput

0.489

High

914383

EFNA4
Ephrin-A4

1

10

High-throughput

0.489

High

936144

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.489

High

1132598

FXYD3
FXYD domain-containing ion transport regulator 3

1

4

High-throughput

0.489

High

1142233

P2RY6
P2Y purinoceptor 6

1

20

High-throughput

0.489

High

1214692

RBM26
RNA-binding protein 26

1

12

High-throughput

0.489

High

1249522

VSTM1
V-set and transmembrane domain-containing protein 1

1

6

High-throughput

0.489

High

1249881

BTNL9
Butyrophilin-like protein 9

1

6

High-throughput

0.489

High

1281719

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

7

High-throughput

0.489

High

1291928

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

20

High-throughput

0.489

High

1325165

TM130
Transmembrane protein 130

1

1

High-throughput

0.489

High

1325964

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

6

High-throughput

0.489

High

1349155

F174A
Membrane protein FAM174A

1

5

High-throughput

0.489

High

1392200

RUSF1
RUS family member 1

1

1

High-throughput

0.489

High

1399652

OPALI
Opalin

1

4

High-throughput

0.489

High

1406557

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

10

High-throughput

0.489

High

1420867

SEM4C
Semaphorin-4C

1

1

High-throughput

0.489

High

1430710

F234A
Protein FAM234A

1

8

High-throughput

0.489

High

1431029

UN93B
Protein unc-93 homolog B1

1

13

High-throughput

0.489

High

1438777

GPR35
G-protein coupled receptor 35

1

20

High-throughput

0.489

High

1453210

GPC5D
G-protein coupled receptor family C group 5 member D

1

2

High-throughput

0.489

High

1458449

HCST
Hematopoietic cell signal transducer

1

3

High-throughput

0.489

High

1460838

CC018
Uncharacterized protein C3orf18

1

2

High-throughput

0.489

High

1461843

CAH14
Carbonic anhydrase 14

1

10

High-throughput

0.489

High

1491707

GPR45
Probable G-protein coupled receptor 45

1

19

High-throughput

0.489

High

1491708

NPTN
Neuroplastin

1

14

High-throughput

0.489

High

894273

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.481

High

951925

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

12

High-throughput

0.481

High

277443

TP4A3
Protein tyrosine phosphatase type IVA 3

1

20

High-throughput

0.479

High

316222

RECQ4
ATP-dependent DNA helicase Q4

1

19

High-throughput

0.479

High

373621

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.479

High

386405

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

12

High-throughput

0.479

High

487931

PARP1
Poly [ADP-ribose] polymerase 1

1

13

High-throughput

0.479

High

582648

PPAP
Prostatic acid phosphatase

1

4

High-throughput

0.479

High

590141

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

610071

VGFR1
Vascular endothelial growth factor receptor 1

1

14

High-throughput

0.479

High

634712

LMNB1
Lamin-B1

1

11

High-throughput

0.479

High

658987

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

15

High-throughput

0.479

High

696982

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

731742

STIP1
Stress-induced-phosphoprotein 1

1

14

High-throughput

0.479

High

769624

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

791878

SYUA
Alpha-synuclein

1

4

High-throughput

0.479

High

800195

COIL
Coilin

1

4

High-throughput

0.479

High

879672

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.479

High

883747

CENPA
Histone H3-like centromeric protein A

1

7

High-throughput

0.479

High

935354

TERA
Transitional endoplasmic reticulum ATPase

1

10

High-throughput

0.479

High

1005286

RNF4
E3 ubiquitin-protein ligase RNF4

1

10

High-throughput

0.479

High

1067882

EP300
Histone acetyltransferase p300

1

19

High-throughput

0.479

High

1108326

SQSTM
Sequestosome-1

1

11

High-throughput

0.479

High

1114767

CUL3
Cullin-3

1

13

High-throughput

0.479

High

1125277

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

7

High-throughput

0.479

High

1126675

GRB7
Growth factor receptor-bound protein 7

1

7

Small-scale

0.479

High

1229800

VIR
Protein virilizer homolog

1

8

High-throughput

0.479

High

1256275

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.479

High

1288617

ZN598
E3 ubiquitin-protein ligase ZNF598

1

13

High-throughput

0.479

High

1312452

ASXL1
Polycomb group protein ASXL1

1

8

High-throughput

0.479

High

1366645

AKAP1
A-kinase anchor protein 1, mitochondrial

1

4

High-throughput

0.479

High

1367693

ESR2
Estrogen receptor beta

1

13

High-throughput

0.479

High

1393880

DDRGK
DDRGK domain-containing protein 1

1

9

High-throughput

0.479

High

1434349

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1438803

NEK6
Serine/threonine-protein kinase Nek6

1

19

High-throughput

0.479

High

1453070

TLS1
Splicing factor C9orf78

1

8

High-throughput

0.479

High

1459022

DAXX
Death domain-associated protein 6

1

3

Small-scale

0.479

High

1459465

ZRAN1
Ubiquitin thioesterase ZRANB1

1

20

High-throughput

0.479

High

1232657

Q6FHY5
MEOX2 protein

1

4

High-throughput

0.470

High

221898

CHM2A
Charged multivesicular body protein 2a

1

5

High-throughput

0.457

High

1273189

CHM1B
Charged multivesicular body protein 1b

1

9

High-throughput

0.457

High

1391155

CHMP6
Charged multivesicular body protein 6

1

12

High-throughput

0.457

High

1417752

CHM4A
Charged multivesicular body protein 4a

1

10

High-throughput

0.457

High

166462

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

6

High-throughput

0.445

High

171624

S27A2
Long-chain fatty acid transport protein 2

1

20

High-throughput

0.445

High

1243534

CSAG1
Chondrosarcoma-associated gene 1 protein

1

4

High-throughput

0.445

High

1366326

LPAR1
Lysophosphatidic acid receptor 1

1

20

High-throughput

0.445

High

1404980

S1PR3
Sphingosine 1-phosphate receptor 3

1

18

High-throughput

0.445

High

412888

NTRK1
High affinity nerve growth factor receptor

1

19

High-throughput

0.437

High

614746

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

15

High-throughput

0.437

High

650511

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.437

High

787111

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

14

High-throughput

0.437

High

889534

CLK1
Dual specificity protein kinase CLK1

1

10

Small-scale

0.437

High

1141384

BRD3
Bromodomain-containing protein 3

1

18

High-throughput

0.437

High

1163451

CAH9
Carbonic anhydrase 9

1

10

Small-scale

0.437

High

1164104

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

20

High-throughput

0.437

High

1249367

LMBRL
Protein LMBR1L

1

6

High-throughput

0.437

High

1277040

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

10

High-throughput

0.437

High

1313894

S15A3
Solute carrier family 15 member 3

1

13

High-throughput

0.437

High

1244127

TMM88
Transmembrane protein 88

1

0

High-throughput

0.426

High

887385

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.408

High

1175

SIM26
Small integral membrane protein 26

1

8

High-throughput

0.407

High

104254

F5H1C8
Solute carrier family 15 member 3

1

13

High-throughput

0.407

High

704097

5HT1E
5-hydroxytryptamine receptor 1E

1

12

High-throughput

0.407

High

732954

GASR
Gastrin/cholecystokinin type B receptor

1

9

High-throughput

0.407

High

771273

APJ
Apelin receptor

1

13

High-throughput

0.407

High

1131653

MFS10
Major facilitator superfamily domain-containing protein 10

1

11

High-throughput

0.407

High

1240993

S27A4
Long-chain fatty acid transport protein 4

1

20

High-throughput

0.407

High

1243683

S27A1
Long-chain fatty acid transport protein 1

1

20

High-throughput

0.407

High

1279106

RIC3
Protein RIC-3

1

1

High-throughput

0.407

High

1289159

OSTA
Organic solute transporter subunit alpha

1

1

High-throughput

0.407

High

1350794

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

3

High-throughput

0.407

High

1381047

S35B4
Nucleotide sugar transporter SLC35B4

1

10

High-throughput

0.407

High

1395679

S35E1
Solute carrier family 35 member E1

1

2

High-throughput

0.407

High

1491706

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

4

High-throughput

0.407

High

1414737

RSRP1
Arginine/serine-rich protein 1

4

0

High-throughput

0.360

High

1358045

TM171
Transmembrane protein 171

3

0

High-throughput

0.347

High

1157355

SSX2
Protein SSX2

2

0

High-throughput

0.316

High

1162642

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.316

High

1336667

ICA1L
Islet cell autoantigen 1-like protein

2

0

High-throughput

0.316

High

231028

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.279

Low

1238262

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

1333455

XXLT1
Xyloside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1417374

CCG6
Voltage-dependent calcium channel gamma-6 subunit

1

0

High-throughput

0.279

Low

1414752

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025