Protein: XPOT
Exportin-T (Exportin(tRNA)) (tRNA exportin)

Gene: XPOT
Organism: Homo sapiens
Interactions: 198
UniProt ID: O43592

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

220893

RAN
GTP-binding nuclear protein Ran

5

19

Small-scale

0.916

High

220906

TRA2A
Transformer-2 protein homolog alpha

2

10

High-throughput

0.783

High

220840

EGFR
Epidermal growth factor receptor

4

13

Small-scale

0.676

High

220881

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

2

High-throughput

0.618

High

220885

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.618

High

220887

RND2
Rho-related GTP-binding protein RhoN

1

11

High-throughput

0.618

High

220891

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.618

High

220892

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.618

High

220894

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.618

High

220897

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.618

High

220912

RHOH
Rho-related GTP-binding protein RhoH

1

8

High-throughput

0.618

High

220934

RHOU
Rho-related GTP-binding protein RhoU

1

10

High-throughput

0.618

High

220995

RHOF
Rho-related GTP-binding protein RhoF

1

11

High-throughput

0.618

High

220841

MYC
Myc proto-oncogene protein

2

10

High-throughput

0.611

High

220889

TPTE
Putative tyrosine-protein phosphatase TPTE

2

9

High-throughput

0.611

High

220835

K2C75
Keratin, type II cytoskeletal 75

2

5

High-throughput

0.606

High

220981

IFT27
Intraflagellar transport protein 27 homolog

1

1

High-throughput

0.575

High

220861

EPHA1
Ephrin type-A receptor 1

2

7

High-throughput

0.574

High

217554

TGON2
Trans-Golgi network integral membrane protein 2

2

2

High-throughput

0.571

High

220896

PO6F2
POU domain, class 6, transcription factor 2

2

1

High-throughput

0.553

High

220834

RHBT1
Rho-related BTB domain-containing protein 1

1

11

High-throughput

0.553

High

220968

RHOV
Rho-related GTP-binding protein RhoV

1

10

High-throughput

0.553

High

220985

RHBT2
Rho-related BTB domain-containing protein 2

1

11

High-throughput

0.553

High

50450

HACL2
2-hydroxyacyl-CoA lyase 2

2

4

High-throughput

0.549

High

220947

MFD4A
Major facilitator superfamily domain-containing protein 4A

2

5

High-throughput

0.549

High

220879

HSP13
Heat shock 70 kDa protein 13

1

6

High-throughput

0.541

High

220838

S1PR4
Sphingosine 1-phosphate receptor 4

1

17

High-throughput

0.536

High

220851

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

4

High-throughput

0.536

High

220852

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.536

High

220858

XRCC1
DNA repair protein XRCC1

1

1

High-throughput

0.536

High

220863

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

13

High-throughput

0.536

High

220886

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.536

High

220899

TIE2
Angiopoietin-1 receptor

1

7

High-throughput

0.536

High

220904

CLN3
Battenin

1

2

High-throughput

0.536

High

220910

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

2

High-throughput

0.536

High

220927

ARMC6
Armadillo repeat-containing protein 6

1

1

High-throughput

0.536

High

220953

ARRD4
Arrestin domain-containing protein 4

1

6

High-throughput

0.536

High

220960

CUL5
Cullin-5

1

7

High-throughput

0.536

High

220970

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

1

High-throughput

0.536

High

220989

UN93B
Protein unc-93 homolog B1

1

10

High-throughput

0.536

High

221006

HDAC6
Protein deacetylase HDAC6

1

8

High-throughput

0.536

High

221009

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

5

High-throughput

0.536

High

221011

FBX7
F-box only protein 7

1

1

High-throughput

0.536

High

221012

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

220876

CCNF
Cyclin-F

1

9

High-throughput

0.515

High

220884

ERF
ETS domain-containing transcription factor ERF

1

4

High-throughput

0.515

High

220966

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.513

High

220898

VIGLN
Vigilin

1

5

Small-scale

0.501

High

220877

ETV3
ETS translocation variant 3

1

4

High-throughput

0.500

High

220913

NTRK3
NT-3 growth factor receptor

1

13

High-throughput

0.500

High

139156

UPK2
Uroplakin-2

1

1

High-throughput

0.489

High

182421

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.489

High

220870

CD70
CD70 antigen

1

3

High-throughput

0.489

High

220888

EFNA4
Ephrin-A4

1

9

High-throughput

0.489

High

220905

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

20

High-throughput

0.489

High

220911

P2RY6
P2Y purinoceptor 6

1

20

High-throughput

0.489

High

220939

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

7

High-throughput

0.489

High

220940

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

20

High-throughput

0.489

High

220967

M4A4A
Membrane-spanning 4-domains subfamily A member 4A

1

2

High-throughput

0.489

High

220973

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

7

High-throughput

0.489

High

220990

S38A1
Sodium-coupled neutral amino acid symporter 1

1

1

High-throughput

0.489

High

220992

SG196
Protein O-mannose kinase

1

1

High-throughput

0.489

High

156725

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.479

High

164188

NRP1
Neuropilin-1

1

1

High-throughput

0.479

High

188736

TMPS2
Transmembrane protease serine 2

1

7

High-throughput

0.479

High

190746

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

220829

AIRE
Autoimmune regulator

1

8

Small-scale

0.479

High

220830

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

220831

CC14B
Dual specificity protein phosphatase CDC14B

1

15

High-throughput

0.479

High

220833

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.479

High

220836

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

220837

SNAI1
Zinc finger protein SNAI1

1

3

High-throughput

0.479

High

220844

HSPB1
Heat shock protein beta-1

1

5

Small-scale

0.479

High

220847

K2C8
Keratin, type II cytoskeletal 8

1

5

High-throughput

0.479

High

220849

ANDR
Androgen receptor

1

9

High-throughput

0.479

High

220850

ARAF
Serine/threonine-protein kinase A-Raf

1

4

High-throughput

0.479

High

220853

AMPN
Aminopeptidase N

1

2

High-throughput

0.479

High

220854

PPAP
Prostatic acid phosphatase

1

4

High-throughput

0.479

High

220855

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

220856

VGFR1
Vascular endothelial growth factor receptor 1

1

10

High-throughput

0.479

High

220866

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

220867

MPIP2
M-phase inducer phosphatase 2

1

3

High-throughput

0.479

High

220869

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

220871

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

220872

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

220874

VGFR3
Vascular endothelial growth factor receptor 3

1

10

High-throughput

0.479

High

220878

ETV6
Transcription factor ETV6

1

1

High-throughput

0.479

High

220880

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.479

High

220895

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

220900

DUSP2
Dual specificity protein phosphatase 2

1

7

High-throughput

0.479

High

220902

EP300
Histone acetyltransferase p300

1

11

High-throughput

0.479

High

220907

CUL3
Cullin-3

1

7

High-throughput

0.479

High

220908

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

5

High-throughput

0.479

High

220909

HAPR1
HUWE1-associated protein modifying stress responses 1

1

3

High-throughput

0.479

High

220914

HIF1A
Hypoxia-inducible factor 1-alpha

1

7

High-throughput

0.479

High

220917

DUS7
Dual specificity protein phosphatase 7

1

8

High-throughput

0.479

High

220919

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

220923

OTU1
Ubiquitin thioesterase OTU1

1

2

High-throughput

0.479

High

220925

VIR
Protein virilizer homolog

1

4

High-throughput

0.479

High

220929

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

220931

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

6

High-throughput

0.479

High

220932

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

220936

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.479

High

220938

ZN598
E3 ubiquitin-protein ligase ZNF598

1

8

High-throughput

0.479

High

220942

ARMC8
Armadillo repeat-containing protein 8

1

10

High-throughput

0.479

High

220944

ASXL1
Polycomb group protein ASXL1

1

4

High-throughput

0.479

High

220946

RHG24
Rho GTPase-activating protein 24

1

9

High-throughput

0.479

High

220951

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.479

High

220954

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

220955

FBX25
F-box only protein 25

1

1

High-throughput

0.479

High

220957

AKAP1
A-kinase anchor protein 1, mitochondrial

1

3

High-throughput

0.479

High

220958

DPF3
Zinc finger protein DPF3

1

2

Small-scale

0.479

High

220961

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.479

High

220962

ARMC5
Armadillo repeat-containing protein 5

1

6

High-throughput

0.479

High

220963

OPTN
Optineurin

1

8

High-throughput

0.479

High

220965

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

220969

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

220971

RUFY1
RUN and FYVE domain-containing protein 1

1

7

High-throughput

0.479

High

220972

RING2
E3 ubiquitin-protein ligase RING2

1

10

High-throughput

0.479

High

220974

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

4

High-throughput

0.479

High

220975

RIOK1
Serine/threonine-protein kinase RIO1

1

7

High-throughput

0.479

High

220978

DUS26
Dual specificity protein phosphatase 26

1

6

High-throughput

0.479

High

220979

RN126
E3 ubiquitin-protein ligase RNF126

1

2

High-throughput

0.479

High

220980

DUS23
Dual specificity protein phosphatase 23

1

16

High-throughput

0.479

High

220982

DUS16
Dual specificity protein phosphatase 16

1

8

High-throughput

0.479

High

220987

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

2

High-throughput

0.479

High

220988

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

220991

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.479

High

220993

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

220994

ECT2
Protein ECT2

1

5

High-throughput

0.479

High

220998

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

221001

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

221003

TLS1
Splicing factor C9orf78

1

5

High-throughput

0.479

High

221004

WWOX
WW domain-containing oxidoreductase

1

3

High-throughput

0.479

High

221005

PD1L1
Programmed cell death 1 ligand 1

1

20

High-throughput

0.479

High

221007

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

221008

HDAC5
Histone deacetylase 5

1

8

High-throughput

0.479

High

220999

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

220901

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

14

High-throughput

0.457

High

166222

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

5

High-throughput

0.445

High

171365

S27A2
Long-chain fatty acid transport protein 2

1

14

High-throughput

0.445

High

220845

A4
Amyloid-beta precursor protein

1

3

Small-scale

0.445

High

220846

JUN
Transcription factor Jun

1

4

High-throughput

0.445

High

220890

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

6

High-throughput

0.445

High

220903

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.445

High

220924

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.445

High

220948

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

220986

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

104895

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

220843

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.437

High

220848

NFM
Neurofilament medium polypeptide

1

6

High-throughput

0.437

High

220857

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

13

High-throughput

0.437

High

220859

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

13

High-throughput

0.437

High

220860

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

13

High-throughput

0.437

High

220862

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.437

High

220864

CATS
Cathepsin S

1

2

High-throughput

0.437

High

220865

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.437

High

220868

UFO
Tyrosine-protein kinase receptor UFO

1

11

High-throughput

0.437

High

220873

BASI
Basigin

1

9

High-throughput

0.437

High

220875

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

10

High-throughput

0.437

High

220883

5HT6R
5-hydroxytryptamine receptor 6

1

6

Small-scale

0.437

High

220915

CAH9
Carbonic anhydrase 9

1

9

Small-scale

0.437

High

220916

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

13

High-throughput

0.437

High

220918

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

19

High-throughput

0.437

High

220920

ANR55
Ankyrin repeat domain-containing protein 55

1

9

High-throughput

0.437

High

220921

TM41B
Transmembrane protein 41B

1

2

High-throughput

0.437

High

220930

LMBRL
Protein LMBR1L

1

5

High-throughput

0.437

High

220935

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

220937

TM11B
Transmembrane protease serine 11B

1

7

High-throughput

0.437

High

220945

S15A3
Solute carrier family 15 member 3

1

9

High-throughput

0.437

High

220949

FBXL6
F-box/LRR-repeat protein 6

1

3

High-throughput

0.437

High

220956

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

12

High-throughput

0.437

High

220959

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

20

High-throughput

0.437

High

220983

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.437

High

221000

TMPS4
Transmembrane protease serine 4

1

7

High-throughput

0.437

High

221002

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

4

High-throughput

0.437

High

221010

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

220882

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

850

SIM26
Small integral membrane protein 26

1

4

High-throughput

0.407

High

104071

F5H1C8
Solute carrier family 15 member 3

1

9

High-throughput

0.407

High

220832

S22A3
Solute carrier family 22 member 3

1

6

High-throughput

0.407

High

220842

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.407

High

220922

S35F1
Solute carrier family 35 member F1

1

1

High-throughput

0.407

High

220926

S35E4
Solute carrier family 35 member E4

1

5

High-throughput

0.407

High

220928

S27A4
Long-chain fatty acid transport protein 4

1

14

High-throughput

0.407

High

220933

S35D2
Nucleotide sugar transporter SLC35D2

1

7

High-throughput

0.407

High

220941

UN93A
Protein unc-93 homolog A

1

10

High-throughput

0.407

High

220943

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

5

High-throughput

0.407

High

220950

MFSD9
Major facilitator superfamily domain-containing protein 9

1

5

High-throughput

0.407

High

220952

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.407

High

220964

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

3

High-throughput

0.407

High

220976

S39A3
Zinc transporter ZIP3

1

5

High-throughput

0.407

High

220984

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

2

High-throughput

0.407

High

220996

S38AA
Solute carrier family 38 member 10

1

1

High-throughput

0.407

High

220977

CNPY3
Protein canopy homolog 3

1

0

High-throughput

0.269

Low

179759

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

220839

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

220997

SHCAF
SIN3-HDAC complex-associated factor

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025