HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 127 Hs			1 3159
+	Hs
		1087343 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		707713 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		229415 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		229321 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		229353 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		229458 H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		658684 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Hs
		658646 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Hs
		241591 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		CHD5_HUMAN (1501-2524): 1.9e-162: 558: 13.68
+	Hs
		707647 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CHD9_HUMAN (1565-2538): 3.24e-144: 509: 13.41
+	Hs
		1307128 H2B1M_HUMAN (1-127): 6.74e-55: 169: 84.25		CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07
+	Hs
		1087418 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07
+	Hs
		707755 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07
+	Hs
		1087210 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		SRCAP_HUMAN (2495-3157): 8.1e-17: 90.5: 14.39
+	Hs
		707663 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		SRCAP_HUMAN (2495-3157): 8.1e-17: 90.5: 14.39
+	Hs
		1087449 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Hs
		707773 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Hs
		846736 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		846990 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		846915 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17